Total Flavonoid Levels of Ethanol Extract of Lemongrass Leaves and Thatch Grass Leaves Using UV-VIS Spectrophotometry

Nuryadin, Yudhi; Naid, Tadjuddin; Dahlia, Andi Amaliah; Dali, Seniwati

doi:10.33368/woh.v1i4.107

Cited by 3 publications

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“…Flavonoid memiliki banyak manfaat bagi kesehatan tubuh diantaranya sebagai antidiabetes, antihipertensi, antikanker, antitumor, antivirus, antibakteri, antijamur, antialergi, antimikroba serta sebagai obat infeksi pada luka. (Nuryadin et al, 2018).…”

Section: Pendahuluanunclassified

Literature Review: Potensi Tanaman Serai (Cymbopogon Citratus) sebagai Antidiabetes

Saldi,

Atifah

2024

masaliq

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The World Health Organization (WHO) explains that more than 220 million people worldwide have diabetes mellitus. Diabetes mellitus is a chronic metabolic disorder caused by not producing enough insulin. Treatment of DM is costly and often has side effects that can be detrimental to the body. Therefore, traditional medicine using herbal plants has begun to be developed at this time. A plant that has the potential as an antidiabetic is lemongrass. This study aims to determine the potential of lemongrass plants as antidiabetics. The method used in writing this article is Literature Review Article (LRA). The database source uses Publis or Perrish. The data used are journal articles published from 2013 to 2023. The results of the literature review that has been carried out know that lemongrass plants have potential as antidiabetics. The antidiabetic ability of lemongrass is due to the presence of secondary metabolite compounds such as flavonoids, tannins, steroids, alkaloids, and triterpenoids contained in lemongrass plants that have the ability to reduce blood glucose levels.

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Section: Pendahuluanunclassified

Literature Review: Potensi Tanaman Serai (Cymbopogon Citratus) sebagai Antidiabetes

Saldi,

Atifah

2024

masaliq

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“…Rendamen ekstrak pada tabel 2 diperoleh sebesar 13,2%, rendamen yang diperoleh lebih besar dari penelitian Rizkita (2017), menggunakan pelarut etanol 70% diperoleh rendamen sebanyak 8.17%. sedangkan Nuryadin et al (2018) dilaporkan daun sereh dapur dengan pelarut etanol didapatkan rendamen sebanyak 3,95%. Maserat dilanjutkan dengan fraksinasi cair-cair dengan pelarut yang mempunyai kepolaran berbeda.…”

Section: Kadar Air Dan Rendamenunclassified

SKRINING FITOKIMIA, TOTAL FLAVONOID DAN FENOLIK DAUN SEREH WANGI (Cymbopogon nardus (L.) Rendle)

2023

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Sereh wangi (Cymbopogon nardus (L.) Rendle) memiliki banyak manfaat dan telah lama dibudidayakan di Indonesia. Senyawa metabolit sekunder terdapat pada semua bahan alam. Penelitian ini bertujuan untuk mengetahui skrining fitokimia, total fenolik, dan total flavonoid ekstrak dan fraksi daun sereh wangi. Daun sereh wangi dimaserasi kemudian difraksinasi dengan pelarut N-heksana, air, dan etil asetat. Uji terdiri dari skrining fitokimia, uji total fenolik dengan standar asam galat, dan total flavonoid menggunakan standar kuersetin. Hasil penelitian menunjukkan bahwa ekstrak mengandung tanin, alkaloid, triterpenoid/steroid, saponin, fenolat, dan flavonoid. Total fenolik pada ekstrak adalah 81,67 mg GAE/sampel; fraksi N-heksana adalah 466,67 mg GAE/sampel; fraksi etil asetat sebesar 369,44 mg GAE/sampel dan fraksi air sebesar 268,89 mg GAE/sampel. Total flavonoid pada ekstrak adalah 161,11 mg QE/g sampel; fraksi N-heksana adalah 239,85 mg GAE/sampel; fraksi etil asetat sebesar 129,48 mg GAE/sampel dan fraksi air sebesar 74,52 mg GAE/sampel.

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“…Maserat hasil maserasi dipekatkan dengan menggunakan rotary evaporator dan diperoleh rendemen sebesar 13.2% rendemen ini lebih tinggi dari penelitian Rizkita (2017) dimana ekstrak daun sereh wangi menggunakanan etanol 70% menghasilkan rendemen sebesar 8.17%. Nuryadin et al (2018) pada daun sereh dapur menggunakan etanol menghasilkan rendemen sebesar 3.95%. Ekstrak kasar etanol sereh wangi dilanjutkan fraksinasi dengan meningkatkan kepolaran menggunakan pelarut yang berbeda-beda sehingga diperoleh senyawa yang sesuai tingkat kepolaran masing-masing.…”

Section: Diskusi Rendemen Ekstrak Dan Fraksi Sereh Wangiunclassified

Antioxidant Activity, Inhibition α-Glucosidase of Cymbopogon nardus (L.) Rendle and Identification of Active Compounds

Najmah,

Hasim,

Faridah

2021

Curr. Biochem.

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Diabetes mellitus (DM) has become a health problem in various countries, even in Indonesia, multiple of Covid-19 sufferers have DM as comorbid. Treatment of DM can be conducted by delaying glucose intake performed by the α-glucosidase enzyme in the intestine. Treatment using synthetic drugs often causes side effects. Instead to overcome these problems, herbal medicine is a choice. Cymbopogon nardus (L.) Rendle served as a potential candidate as seen from prior research but related to DM drugs, further exploration needs to be performed. This study aims to acquire a DM medicine by using Cymbopogon nardus (L.) Rendle . The leaves were macerated using 96% concentration of ethanol followed by multilevel fractionation with n-hexane, water and ethyl acetate as solvents. The test results showed that the n-hexane fraction was the best for antioxidant activity and α -glucosidase inhibition with IC50 values of 8,23 ppm and 311,87 ppm while the identification of the compound by using Liquid Chromatograph-Mass Spectrometry (LC-MS/MS) suspected compounds that have a role were ar-turmerone, beesioside N and notohamosin A. Based on the test, the n-hexane fraction was found as a source of antioxidants as well as α -glucosidase inhibitors. Keywords: Antioxidant, α -glucosidase, Cymbopogon nardus (L.) Rendle, LC-MS/MS.

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Total Flavonoid Levels of Ethanol Extract of Lemongrass Leaves and Thatch Grass Leaves Using UV-VIS Spectrophotometry

Cited by 3 publications

References 0 publications

Literature Review: Potensi Tanaman Serai (Cymbopogon Citratus) sebagai Antidiabetes

Literature Review: Potensi Tanaman Serai (Cymbopogon Citratus) sebagai Antidiabetes

SKRINING FITOKIMIA, TOTAL FLAVONOID DAN FENOLIK DAUN SEREH WANGI (Cymbopogon nardus (L.) Rendle)

Antioxidant Activity, Inhibition α-Glucosidase of Cymbopogon nardus (L.) Rendle and Identification of Active Compounds

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