Total Diet Studies as a Tool for Ensuring Food Safety

Lee, Joon‐Goo; Kim, Sheen-Hee; Kim, Hae-Jung; Yoon, Hyung Joon

doi:10.5487/tr.2015.31.3.221

Cited by 13 publications

(10 citation statements)

References 15 publications

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“…19 There are two obvious advantages of a TDS: (1) the composite samples used in a TDS are aggregates of many subsamples collected on a large scale, which is a cost-effective and suitable method for the complex analysis of chemicals; and (2) the chemicals analyzed in a TDS are in a consumable form because they are extracted from cooked food. 20 For analytically complex compounds such as CPs, a TDS is an efficient tool to monitor human dietary exposure nationwide. Iino et al 21 found that fat samples from the first Japanese market basket study had the highest SCCP concentrations, followed by shellfish and fish samples.…”

Section: ■ Introductionmentioning

confidence: 99%

Short- and Medium-Chain Chlorinated Paraffins in Foods from the Sixth Chinese Total Diet Study: Occurrences and Estimates of Dietary Intakes in South China

Cui

Gao

Zheng

et al. 2020

J. Agric. Food Chem.

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Food consumption has been identified as a major pathway for human exposure to short-chain chlorinated paraffins (SCCPs) and medium-chain chlorinated paraffins (MCCPs), but evaluations of SCCP and MCCP intake from major dietary sources are limited. We used the sixth Chinese Total Diet Study to perform a comprehensive investigation of SCCPs and MCCPs in cereals, vegetables, potatoes, legumes, eggs, milk, meats, and aquatic foods from nine southern provinces. The geographical distribution of CP concentrations showed higher levels in Jiangsu, Hubei, and Zhejiang provinces. The CP concentrations in most animal-origin foods were higher than those in foods of plant origin. The total estimated daily intakes (EDIs) of SCCPs and MCCPs, with average values of 7.0 × 102 and 4.7 × 102 ng kg–1 day–1, respectively, were mostly contributed by cereals, vegetables, and meats. Risk assessment indicated the EDIs of CPs posed no significant risk to residents in South China.

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Section: ■ Introductionmentioning

confidence: 99%

Short- and Medium-Chain Chlorinated Paraffins in Foods from the Sixth Chinese Total Diet Study: Occurrences and Estimates of Dietary Intakes in South China

Cui

Gao

Zheng

et al. 2020

J. Agric. Food Chem.

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“…Risk analysis has been recommended as one of the most effective measurements for managing food safety against globalized food scams and scandals. A risk analysis comprising three components, namely, risk assessment, risk management, and risk communication, is used to respond to food accidents and develop safety standards (Lee et al 2015 ). Figure 3 shows the paradigm of risk analysis and its comprising factors (B.M.J.…”

Section: Effects Of Codex On Korean Food Safety Management Systemsmentioning

confidence: 99%

Codex Alimentarius commission on ensuring food safety and promoting fair trade: harmonization of standards between Korea and codex

Lee

Kim

et al. 2021

Food Sci Biotechnol

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Korea’s overall food safety management policies reflect the Codex guidelines in terms of risk analysis and standards. Korea’s food safety management plan, which is established every 3 years, includes the pre-emptive management of risk factors and provides food safety information on the basis of scientific evidence. Since officially joining Codex as a member country in 1971, Korea has led the establishment of six Codex standards, including those for Kimchi and Gochujang . Moreover, Korea’s food standards are harmonized with Codex’s risk assessment system. This review aims to examine the current status and trends of Codex and to summarize and compare the food safety management systems and food standards between Korea and Codex.

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“…From the studies presented in Table 2, Sirot et al (2013) and Sprong et al (2016a) evaluated the exposure of French and Dutch populations, respectively, to mycotoxins.. According to Lee et al (2015), countries as Australia, France, Korea and China had developed their country-specific TDSs including mycotoxins but all countries are encouraged to conduct total diet studies to assess the safety and nutritional quality of diet of their population since TDS is not only a costeffective tool but also a realistic tool for risk assessment of chemicals in foods. Actually, the TDS EXPOSURE project aims to provide guidance for future TDSs, as well as for new TDSs in countries that have no TDS experience (http:// tds-exposure.eu/).…”

Section: Worldwide Exposure Assessment Of Co-occurring Mycotoxins In mentioning

confidence: 99%

Challenges in risk assessment of multiple mycotoxins in food

Assunção

Silva

Alvito

2016

WMJ

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Most fungi are able to produce several mycotoxins simultaneously and, consequently, to contaminate a wide variety of foodstuffs. Therefore, the risk of human co-exposure to multiple mycotoxins is real, raising a growing concern about their potential impact on human health. Besides, government and industry regulations are usually based on individual toxicities, and do not take into account the complex dynamics associated with interactions between co-occurring groups of mycotoxins. The present work assembles, for the first time, the challenges posed by the likelihood of human co-exposure to these toxins and the possibility of interactive effects occurring after absorption, towards knowledge generation to support a more accurate human risk assessment. Regarding hazard assessment, a physiologically-based framework is proposed in order to infer the health effects from exposure to multiple mycotoxins in food, including knowledge on the bioaccessibility, toxicokinetics and toxicodynamics of single and combined toxins. The prioritisation of the most relevant mixtures to be tested under experimental conditions that attempt to mimic human exposure and the use of adequate mathematical approaches to evaluate interactions, particularly concerning the combined genotoxicity, were identified as the main challenges for hazard assessment. Regarding exposure assessment, the need of harmonised food consumption data, availability of multianalyte methods for mycotoxin quantification, management of left-censored data, use of probabilistic models and multibiomarker approaches are highlighted, in order to develop a more precise and realistic exposure assessment. To conclude, further studies on hazard and exposure assessment of multiple mycotoxins, using harmonised methodologies, are crucial towards an improvement of data quality and a more reliable and robust risk characterisation, which is central for risk management and, consequently, to prevent mycotoxins-associated adverse effects. A deep understanding of the nature of interactions between multiple mycotoxins will contribute to draw real conclusions on the health impact of human exposure to mycotoxin mixtures.

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Total Diet Studies as a Tool for Ensuring Food Safety

Cited by 13 publications

References 15 publications

Short- and Medium-Chain Chlorinated Paraffins in Foods from the Sixth Chinese Total Diet Study: Occurrences and Estimates of Dietary Intakes in South China

Short- and Medium-Chain Chlorinated Paraffins in Foods from the Sixth Chinese Total Diet Study: Occurrences and Estimates of Dietary Intakes in South China

Codex Alimentarius commission on ensuring food safety and promoting fair trade: harmonization of standards between Korea and codex

Challenges in risk assessment of multiple mycotoxins in food

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