Topical effectiveness of kiwifruit versus fibrinolysin ointment on removal of necrotic tissue of full-thickness burns in male rats

Abstract

Formation of necrotic tissues is a major issue affecting treatment of full-thickness burns. This study was designed to compare topical effectiveness of applying kiwifruit versus fibrinolysin on removal of necrotic tissue of burns. Ten adult male Wistar rats were randomly assigned to three groups. For group 1, the right-side wounds were treated with kiwifruit and the other side with fibrinolysin. For group 2, the wounds on the right side were treated with kiwifruit or fibrinolysin, and the left sides were kept as control group 2. All wounds in group 3 were considered as control group 1. The control wounds were left to heal naturally. In each group and for each wound, the time of debridement were noted. The results indicated that for the wounds where kiwifruit was applied, the average time for removal of dead tissue was 5.7 days, which is significantly shorter than the average 18.5 days it took for treatment with fibrinolysin (p = 0.02). However, there were no significant differences between control wounds 1 and 2. Findings of the present study can open new horizons and provide a new treatment modality for patients with deep burns.

The effects of topical vitamin C solution on the necrotic tissue volume of burn wounds

“…Moreover, eight people were reported to die each day due to burn injuries in 2002 in Iran. Percentage of burn injury deaths in our country is almost three times higher compared to the Eastern Mediterranean region, while twice higher than the global mortality rate (6).…”

Gum Arabic and Tricalcium Phosphate as Encapsulating Agents during kiwifruit Drying

“…The consumption of "Hayward" kiwifruit in the evening has been shown to improve sleep onset, duration, and efficiency in adults with self-reported sleep disturbances [15]. In addition, the application of kiwifruit fresh slices to burns has been shown to improve the healing process [16].…”