Tissue distribution of decabrominated diphenyl ether (BDE-209) and its metabolites in sucking rat pups after prenatal and/or postnatal exposure

Zhang, Wenbing; Cai, Yunmei; Sheng, Guoying; Chen, Dunjin; Fu, Jiamo

doi:10.1016/j.tox.2011.02.003

Cited by 34 publications

(20 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In recent years, there have been several rodent studies that described the accumulation of BDE-209 in limited tissues after oral dosing with the chemical (Morck et al, 2003;Huwe and Smith, 2007;Riu et al, 2008;Wang et al, 2010;Zhang et al, 2011), but less information has been available about its internal body burden after long-term exposure. In a dietary study reported by Norris et al (1975) in which Sprague-Dawley rats were maintained on diets providing up to 1.0 mg kg À1 per day of a former commercial DecaBDE (FR-300-BA, composed of 77.4% BDE-209), bromine concentrations in some tissues of the treated rats were comparable to that of controls after 6 months and 12 months of treatment.…”

Section: Body Burden and Biodistribution Of Bde-209 In The Exposed Micementioning

confidence: 99%

Simulating long-term occupational exposure to decabrominated diphenyl ether using C57BL/6 mice: Biodistribution and pathology

Feng

Meng

et al. 2015

Chemosphere

View full text Add to dashboard Cite

Section: Body Burden and Biodistribution Of Bde-209 In The Exposed Micementioning

confidence: 99%

Simulating long-term occupational exposure to decabrominated diphenyl ether using C57BL/6 mice: Biodistribution and pathology

Feng

Meng

et al. 2015

Chemosphere

View full text Add to dashboard Cite

“…This phenomenon was also observed in birds and rodents (Voorspoels et al, 2006;Zhang et al, 2011). It is suggested that the blood-brain barrier (BBB) could protect to some degree the brain from PBDE accumulation (Bachour et al, 1998;Voorspoels et al, 2006).…”

Section: Tablementioning

confidence: 72%

Changes of polybrominated diphenyl ether concentrations in ducks with background exposure level and time

Liu¹,

Chen²,

Zhao³

et al. 2015

Chemosphere

View full text Add to dashboard Cite

h i g h l i g h t sWe conducted a semi-field experiment of ducks in an e-waste recycling site. PPBDEs increased in fat with time, but fluctuated in other tissues with exposure level. High brominated DE levels increased with time but low brominated DE fluctuated in fat. High brominated DEs seem to have longer half-lives than low brominated DEs in fat. a r t i c l e i n f o b s t r a c tTo reveal what degree bioaccumulation of polybrominated diphenyl ethers (PBDEs) depends on exposure time and other factors, we conducted a semi-field experiment for a year (June 2008-June 2009) in a village in an e-waste recycling site in Taizhou, China. Approximately one hundred of juvenile ducks (Anas domestica Linnaeus) were entrusted to a villager. The ducks lived and forged in a PBDE-polluted pond from the late March to the end of November. Fish and mudsnails that were heavily polluted by PBDEs were main food. In cold days (from December to the middle March), the ducks lived in the villager' house, and mainly fed on paddy, which contained lower concentrations of PBDEs than fish and mudsnails. The female ducks were sampled for PBDE analysis every three months. We found that the P PBDE concentrations in duck liver, muscle, lung and brain fluctuated greatly with the changes of exposure levels that were determined by the environment and diets, but the P PBDE concentrations in fat tissue increased successively with time. Congener analysis demonstrated that the successive increase in the P PBDE concentrations with time in fat tissue was due to the successive increase in concentrations, with large fluctuations of low brominated congeners. The results show that PBDE concentrations in liver, muscle, lung and brain tissues heavily depends on exposure levels rather than exposure time. In fat tissue, by contrast, PBDE concentrations (mainly high brominated congeners) slightly depends on exposure levels but heavily depend on time relative to other tissues, implying that high brominated congeners seem to have longer half-lives than low brominated congeners in fat tissue.

show abstract

“…Trace of octa-BDEs was also detected but below the quantification detection limit. So in our papers Zhang et al, 2011) the purity of BDE-209 was given as >98%. Additionally, we also noted that the purity of >98% BDE-209 in this commercial product has also been reported by other researchers (Deng et al, 2011;Yu et al, 2010).…”

Section: Response To the Letter From Biesemeier Et Almentioning

confidence: 96%

Response to the Letter from Biesemeier et al.

et al. 2011

Self Cite

View full text Add to dashboard Cite

Tissue distribution of decabrominated diphenyl ether (BDE-209) and its metabolites in sucking rat pups after prenatal and/or postnatal exposure

Cited by 34 publications

References 31 publications

Simulating long-term occupational exposure to decabrominated diphenyl ether using C57BL/6 mice: Biodistribution and pathology

Simulating long-term occupational exposure to decabrominated diphenyl ether using C57BL/6 mice: Biodistribution and pathology

Changes of polybrominated diphenyl ether concentrations in ducks with background exposure level and time

Response to the Letter from Biesemeier et al.

Contact Info

Product

Resources

About