TIRYAQ E ARBA: A classical Unani Formulation to boost immunity

Khan, Asim Ali; Bashir, Fouzia; Akhtar, Jamal

doi:10.22270/jddt.v10i4-s.4312

Cited by 4 publications

(5 citation statements)

References 10 publications

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“…One of the important preparations called Tiryaq‐e‐Arba consists of Gentiana lutea L., Aristolochia longa L, Commiphora myrrha (Nees) Engl, and Laurus nobilis L. This preparation is mainly used as an immune booster to fight epidemics (A. A. Khan, Bashir, & Akhtar, 2020 ).…”

Section: Resultsmentioning

confidence: 99%

Promising traditional Indian medicinal plants for the management of novel Coronavirus disease: A systematic review

Singh

Kaur

et al. 2021

Phytotherapy Research

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Traditional Indian medical practices (Ayurveda, Siddha, Unani, and homeopathy) are a vast reservoir of knowledge about medicinal plants. The promising pharmacological properties of these plants have paved the way for developing therapy against novel Coronavirus (CoV) infection. The current review will summarize published works of literature on the effects of traditional Indian medicinal plants against acute respiratory infection (COVID‐19, SARS, Influenza, and Respiratory syncytial virus infection) and registered clinical trials of traditional Indian herbal medicines in COVID‐19. The current study aims to comprehensively evaluate the data of traditional Indian medicinal plants to warrant their use in COVID‐19 management. PubMed, Embase, and Cochrane databases were searched along with different clinical trial databases. A total of 22 relevant traditional Indian medicinal plants (35 relevant studies) were included in the current study having potential antiviral properties against virus‐induced respiratory illness along with promising immunomodulatory and thrombolytic properties. Further, 36 randomized and nonrandomized registered clinical trials were also included that were aimed at evaluating the efficacy of herbal plants or their formulations in COVID‐19 management. The antiviral, immunomodulatory, and thrombolytic activities of the traditional Indian medicinal plants laid down a strong rationale for their use in developing therapies against SARS‐CoV‐2 infection. The study identified some important potential traditional Indian medicinal herbs such as Ocimum tenuiflorum, Tinospora cordifolia, Achyranthes bidentata, Cinnamomum cassia, Cydonia oblonga, Embelin ribes, Justicia adhatoda, Momordica charantia, Withania somnifera, Zingiber officinale, Camphor, and Kabusura kudineer, which could be used in therapeutic strategies against SARS‐CoV‐2 infection.

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Section: Resultsmentioning

confidence: 99%

Promising traditional Indian medicinal plants for the management of novel Coronavirus disease: A systematic review

Singh

Kaur

et al. 2021

Phytotherapy Research

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“…Unani add-on regimen includes a semisolid Unani pharmacopeial preparation-'Tiryaq-e-Arba', an Unani antidote for epidemics which comprises equal proportions of four herbs prepared as per the Unani Formulary, along with 'Unani Joshanda', a decoction made with three herbs. In order to obtain decoction, all three ingredients of 'Unani Joshanda', were boiled in 250 ml of water and reduced to one-half (125ml), followed by filtration [4,8,11,15,19,20]. Both the herbal Unani drug preparation were supplied by the Indian Medicines Pharmaceutical Corporation Limited (IMPCL) which is engaged in the Manufacturing and Marketing of Ayurvedic and Unani Medicines and is under the administrative control of the Ministry of AYUSH, Govternment of India.…”

Section: Study Interventionsmentioning

confidence: 99%

“…All the individual ingredients of the combination exhibit anti-viral activity in addition to anti-inflammatory, antioxidant, and immunomodulatory properties [4][5][6][7][8][9][10][11][12][13][14][15][16][17]. Recently, it was also reported that it exhibits antiviral activity against SARS-CoV-2 [5].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of the Unani Regimen as an Add-On to Standard Treatment in Hospitalised RT-PCR-Confirmed Mild to Moderate COVID-19 Patients: An Open-Label Randomized Controlled Trial

Kishore¹,

Kumar²,

Nazli³

et al. 2023

Cureus

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Background The coronavirus disease 2019 (COVID-19) pandemic resulted in mortality and morbidity worldwide. Many treatment modalities have been experimented with limited success. Therefore, the traditional system of medicine needs to be explored. Objective To evaluate the benefits of Unani regimens Tiryaq-e-Arba and Unani Joshanda, as adjuvant therapy, were compared to standard treatment alone among reverse transcription polymerase chain reaction (RT-PCR)-confirmed mild to moderate COVID-19 cases. Materials and methods An open-label, double-arm, randomized, controlled interventional clinical study was conducted among 90 RT-PCR-confirmed mild to moderate COVID-19 inpatients admitted to a tertiary care hospital in New Delhi, India. Participants who fulfilled the criteria for inclusion were randomly assigned to two arms, with 43 subjects allocated to the Unani add-on arm and 47 subjects to the control arm receiving standard treatment alone. Results Clinical recovery was achieved in all patients of the Unani arm, while in the control arm, three (6.4%) patients deteriorated and had to be shifted to ICU following admission. In the intervention arm, a shorter duration of hospitalization was observed (mean 5.95 days {SD = 1.99}) than in the control arm (mean 7.62 days {SD, 4.06}); which was a statistically significant difference (p-value 0.017). The majority of the patients recovered within 10 days in the Unani add-on arm. The number of days taken for the reduction of symptoms was significantly less in the intervention arm (mean 5.14 days {SD, 2.39}) as compared with standard treatment (mean 6.53 days {SD, 3.06}) (p < 0.02). Renal and liver safety parameters were within the normal limits in both arms and no serious adverse event was reported. Conclusion Adding Unani formulations to standard treatment significantly reduced the duration of hospital stay and showed early recovery in COVID-19 patients compared with the control arm. It may be concluded that the synergistic effect of the Unani add-on with standard treatment gave more promising results in mild to moderate COVID-19 patients.

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“…IIkhani et al (2019), Baig et al (2018) studied relationship between Temperament and diabetes [33][34]. In the current epoch, the importance of Temperament in dealing with COVID 19 were studied by Nikhat and Fazil (2020), Khan et al (2020) [35][36].…”

Section: -2-unani Temperament (Mizaj)mentioning

confidence: 99%

Mathematical Modelling of the Relationship between Two Different Temperament Classifications: During the Covid-19 Pandemic

et al. 2021

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In medicine, it is well known that healthy individuals have different physical and mental characteristics. Ancient Indian medicine, Ayurveda and the Persian-Arabic traditional Unani medicine has two distinct approaches for the classification of human subjects according to their temperaments. The individual temperament is an important foundation for personalized medicine, which can help in the prevention and treatment of many diseases including COVID-19. This paper attempts to explore the relationship of the utmost important concepts of these systems called individual temperament named as Prakruti in Ayurveda and Mizaj in Unani practice using mathematical modelling. The results of mathematical modelling can be adopted expediently for the development of algorithms that can be applied in medical informatics. For this, a significant literature review has been carried out. Based on the previous researchers' reviews the essential parameters have been identified for making the relationship and hypothesis were framed. The mathematical modelling was adopted to propose the existence of the relationship between the parameters of such an ancient and rich medicine systems. The hypotheses are validated through the mathematic driven model. Doi: 10.28991/esj-2021-01258 Full Text: PDF

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TIRYAQ E ARBA: A classical Unani Formulation to boost immunity

Cited by 4 publications

References 10 publications

Promising traditional Indian medicinal plants for the management of novel Coronavirus disease: A systematic review

Promising traditional Indian medicinal plants for the management of novel Coronavirus disease: A systematic review

Efficacy of the Unani Regimen as an Add-On to Standard Treatment in Hospitalised RT-PCR-Confirmed Mild to Moderate COVID-19 Patients: An Open-Label Randomized Controlled Trial

Mathematical Modelling of the Relationship between Two Different Temperament Classifications: During the Covid-19 Pandemic

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