Tinospora cordifolia (Giloy) - Therapeutic Uses and Importance: A review

Saxena, Charu; Rawat, Geeta

doi:10.24092/crps.2019.090302

Cited by 7 publications

(8 citation statements)

References 3 publications

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“…Anti-diabetic activities are attributed to tannins, cardiac glycosides, flavonoids, saponins, alkaloids such as magnoflorine, palmetine, and jatrorrhizine, and other substances. When rats were given an aqueous extract lacking Tinospora cordifolia extract, glucose levels rose 21.3 percent, insulin levels rose 51.5 percent, triglycerides rose 54.12%, and the glucose insulin index rose 59.8% [4] .…”

Section: Anti-diabetic Activitymentioning

confidence: 99%

“…The active constituents of the giloy plant can be extracted from many portions of the plant, such as the leaves, stems, and roots (Table 1) [4] .…”

Section: Active Constituents Of the Tinospora Cordifoliamentioning

confidence: 99%

“…Diabetes mellitus is a chronic disorder of carbohydrates, fats and protein metabolism. A defective or deficient insulin secretary response, which translates into impaired carbohydrates (glucose) use, is a characteristic feature of diabetes mellitus, as is the resulting hyperglycemias Diabetes mellitus (DM) is commonly referred to as a "sugar" and it is the most common endocrine disorder and usually occurs when there is deficiency or absence of insulin or rarely, impairment of insulin activity (insulin resistance) [11] .…”

Section: Diabetesmentioning

confidence: 99%

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Formulations and evaluation of antidiabetic Tinospora cordifolia powder

Bais,

Dhavre,

Devmare

2023

Int. J. Pharmacognosy Life Sci.

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Humanity has used medicinal plants for their therapeutic benefits ever since the dawn of civilization. For thousands of years, nature has served as a source for therapeutic substances, and an astounding number of contemporary medications have been identified from natural sources. The primary healthcare system of resource-poor areas in India has continued to rely on traditional medicine as the most accessible and reasonably priced form of treatment. Tinospora cordifolia is a shrub that is frequently utilised in Ayurvedic and folk medicine throughout India. Although practically all of its parts are employed in traditional medical systems, the most significant portions that are used medicinally are the leaves, stems, and roots. It is a member of the Menispermaceae family. One of the most adaptable herbs for rejuvenation, guduchi has a wide range of medicinal benefits. Guduchi's Madhu mehahara (Anti-diabetic) characteristics are highly valued in Ayurveda and even in more recent scientific studies. In the present study, GS prepared from the stem of T. cordifolia was evaluated forhypoglycemic and Antidibetic. GS was powder dissolve in distilled water and administered to oral route of powder dosage form. Present review encompasses (i) in-depth information of antidiabetic potential of Guduchi and its various dosageforms from Ayurvedic view and (ii) to understand the possible mechanism of its action in combating the complex pathology of diabetes. In the current study, the hypoglycemic and antidiabetic effects of GS made from T. cordifolia stem were assessed. GS was given as a powder dose form that was dissolved in distilled water and swallowed. The current review includes (i) in-depth analysis of Guduchi's antidiabetic potential and its many dosageforms from an Ayurvedic perspective, as well as (ii) an understanding of its probable mechanisms of action in addressing the intricate pathology of diabetes.

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Section: Anti-diabetic Activitymentioning

confidence: 99%

“…The active constituents of the giloy plant can be extracted from many portions of the plant, such as the leaves, stems, and roots (Table 1) [4] .…”

Section: Active Constituents Of the Tinospora Cordifoliamentioning

confidence: 99%

Section: Diabetesmentioning

confidence: 99%

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Formulations and evaluation of antidiabetic Tinospora cordifolia powder

Bais,

Dhavre,

Devmare

2023

Int. J. Pharmacognosy Life Sci.

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“…Protein, Ca, and P content are also moderately high in giloy leaves. [7] Diabetes mellitus is cured by a variety of phytoconstituents which are isolated from various sections of T. cordifolia. Alkaloids, tannins, and cardiac glycosides are some of these phytochemicals.…”

Section: Fig1 Tinospora Cordifolia Leaves and Barkmentioning

confidence: 99%

Herbal Aqueous Extract Used For Treatment Of Diabetes Mellitus (Type-2).

Prajapati,

Chhipa,

Patani

2024

jaz

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Diabetes is a lifelong (chronic) disease and is a group of metabolic disorders characterized by a high level of sugar in the blood [Hyperglycemia]. It is caused due to deficiency of insulin (diabetes insipidus) or resistance to insulin (diabetes mellitus). Insulin is secreted by β-cells of the pancreas to control blood sugar level. Both diabetes insipidus and diabetes mellitus can be treated with a variety of herbal plants, such as Tinospora cordifolia, Withania somnifera, Momordica charantia, Cinnamomum zeylanicum, Allium sativum, Panax ginseng, Gymnema sylvestre, Trigonella foenum graecum, and Azadirachta indica. Each of these medicinal plants has an anti-diabetic action, and their aqueous extracts are used to treat diabetes.

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“…Bioactive compounds of giloy help immune system to fight infections and upholdthe functioning of leucocyte [31]. In a study, cordifolioside A, magnoflorine, β-ecdysone and palmatine were found to be the main phytocompounds in Giloy [32]. Giloy is known for its property that improvesimmunity.…”

Section: Tinospora Cordifoliamentioning

confidence: 99%

A Review on Some Indigenous Medicinal Plants and their Key Applications

Sharma

Tripathi

2021

JPRI

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In India, 7,500 plant species out of 17,000 are officially integrated in ayurvedic pharmacopeia for over a millennium. There are many industrial uses of medicinal plants which include traditional medicines, phytopharmaceuticals, herbal teas, health food etc. Now days, in silico approaches have been developed which is used in virtual screening and analysis of medicinal plants to be used pharmacologically. It is a cost effective and efficient way for the production of new drugs which is done in three basic steps i.e. molecular docking, developing pharmacophores and determining molecular similarity in shape. WHO has also acknowledged the importance of medicinal plants and has created various guidelines and strategies to encourage its use. Agro industrial technologies also encourage the use of medicinal plants. India has wide variety of plant species in its ecosystem. Out of 17,000 species of plants 7,500 species are used as medicinal plants by the tribal groups, villagers and in traditional medicinal systems like Ayurveda. The aim of the review is to summarize the information on the recent development in the field of medicinal plants and their key applications.

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Tinospora cordifolia (Giloy) - Therapeutic Uses and Importance: A review

Cited by 7 publications

References 3 publications

Formulations and evaluation of antidiabetic Tinospora cordifolia powder

Formulations and evaluation of antidiabetic Tinospora cordifolia powder

Herbal Aqueous Extract Used For Treatment Of Diabetes Mellitus (Type-2).

A Review on Some Indigenous Medicinal Plants and their Key Applications

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