Tinea nigra: successful treatment with topical butenafine

Rossetto, André Luiz; Cruz, Ramón

doi:10.1590/s0365-05962012000600025

Cited by 13 publications

(5 citation statements)

References 5 publications

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“…The clinical presentation is generally a single hyperchromic macule, not symptomatic, in palms and soles, but there is a report of isolation of H. werneckii from blood and splenic abscess [12]. Treatment is usually done by topic or oral administration of antifungal agents [7,[13][14][15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Enzymatic Activity and Susceptibility to Antifungal Agents of Brazilian Environmental Isolates of Hortaea werneckii

et al. 2015

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Four strains of Hortaea werneckii were isolated from different substrates in Brazil (a salt marsh macrophyte, a bromeliad and a marine zoanthid) and had their identification confirmed by sequencing of the 26S rDNA D1/D2 domain or ITS region. Most of the strains were able to express amylase, lipase, esterase, pectinase and/or cellulase, enzymes that recognize components of plant cells as substrates, but did not express albuminase, keratinase, phospholipase and DNAse, whose substrates are animal-related. Urease production was positive for all isolates, while caseinase, gelatinase and laccase production were variable among the strains. All the strains grew in media containing up to 30% NaCl. We propose that the primary substrate associated with H. werneckii is plant-related, in special in saline environments, where the fungus may live as a saprophyte and decomposer. Infection of animal-associated substrates would be secondary, with the fungus acting as an opportunistic animal pathogen. All strains were resistant to fluconazole and presented high MIC for amphotericin B, while they were susceptible to all the other antifungal agents tested.

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Section: Introductionmentioning

confidence: 99%

Enzymatic Activity and Susceptibility to Antifungal Agents of Brazilian Environmental Isolates of Hortaea werneckii

et al. 2015

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“…Tinea nigra is usually seen in tropical and subtropical climates, and affects those under the age of 20, especially females. 65,67,68 Eccrine glands are the most affected structures. The fungus exhibits lipophilic adhesion to human skin; it is exclusively found in the stratum corneum.…”

Section: Tinea Nigramentioning

confidence: 99%

“…Scanning electron microscopy can be useful in the diagnosis of tinea nigra. 65,67,68 Although spontaneous cures may occasionally occur, various topical antifungals such as isoconazole, ketoconazole, bifanazole, terbinafine, Whitfield's ointment, and butenafine can be effective in the treatment of tinea nigra. 66,68,71,72 …”

Section: Tinea Nigramentioning

confidence: 99%

Acral manifestations of fungal infections

Kutlubay

Yardımcı

Kantarcıoğlu

et al. 2017

Clinics in Dermatology

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“…In the literature, there are also case reports of spontaneous cure of this mycosis. 1 - 4 , 9 , 16 - 18 …”

Section: Introductionmentioning

confidence: 99%

Scanning electron microscopy of tinea nigra

Guarenti

Almeida

Leitão

et al. 2014

An. Bras. Dermatol.

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Tinea nigra is a rare superficial mycosis caused by Hortaea werneckii. This infection presents as asymptomatic brown to black maculae mostly in palmo-plantar regions. We performed scanning electron microscopy of a superficial shaving of a tinea nigra lesion. The examination of the outer surface of the sample showed the epidermis with corneocytes and hyphae and elimination of fungal filaments. The inner surface of the sample showed important aggregation of hyphae among keratinocytes, which formed small fungal colonies. The ultrastructural findings correlated with those of dermoscopic examination - the small fungal aggregations may be the dark spicules seen on dermoscopy - and also allowed to document the mode of dissemination of tinea nigra, showing how hyphae are eliminated on the surface of the lesion.

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Tinea nigra: successful treatment with topical butenafine

Cited by 13 publications

References 5 publications

Enzymatic Activity and Susceptibility to Antifungal Agents of Brazilian Environmental Isolates of Hortaea werneckii

Enzymatic Activity and Susceptibility to Antifungal Agents of Brazilian Environmental Isolates of Hortaea werneckii

Acral manifestations of fungal infections

Scanning electron microscopy of tinea nigra

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