Time Course of Changes in Ocular Aberrations After Instillation of Carteolol Long-Acting Solution and Timolol Gel-Forming Solution

Hiraoka, Takahiro; Daito, Masakazu; Okamoto, Fumiki; Kiuchi, Takahiro; Oshika, Tetsuro

doi:10.1089/jop.2010.0149

Cited by 9 publications

(7 citation statements)

References 28 publications

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“…13 Only few publications address the problem of dry eye syndrome and usage of eye drops before performing keratometry. 10,[14][15][16] Montes-Mico and associates demonstrated, in agreement with our results, a significant change of total, spherelike and commalike aberrations after the application of artificial tears. 11 In contrast to our results, this change was still significant 5 and 10 minutes after instillation.…”

Section: Discussionsupporting

confidence: 93%

Influence of Artificial Tears on Keratometric Measurements in Cataract Patients

Röggla

Leydolt

Schartmüller

et al. 2021

American Journal of Ophthalmology

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PATIENT POPULATION: A total of 123 eyes of 80 patients prior to cataract surgery were assigned to 2 groups based on normal and dry eyes. INTERVENTION: Two native baseline keratometries were followed by instillation of either high-or low-viscosity eye drops. Keratometry was repeated 30 seconds, 2 minutes, and 5 minutes after instillation. MAIN OUTCOME MEASURES: Influence of eye drops of different viscosity in normal and dry eyes on short time K-readings.RESULTS: Repeatability between native baseline measurements was high (standard deviation [ 0.02 mm in normal and in dry eyes). In normal and dry eyes, a statistically significant increase in measurement variability after instillation of both low-viscosity and high-viscosity eye drops was observed (P < .01). Measurement variability was most pronounced between baseline measurement and 30 seconds and diminished over time. Variability of K-readings appeared higher in dry eyes compared with normal eyes. Astigmatism changed more than 0.5 diopters in 13.2% of normal eyes and 34.4% in dry eyes using eye drops of high viscosity.CONCLUSION: Tear film-stabilizing eye drops prior to keratometry measurements influenced K-readings significantly, especially in dry eyes. A time period of more than 5 minutes should be allowed to pass after instillation of eye drops. The higher the viscosity of the eye drops, the stronger the influence and the longer its persistence.

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Section: Discussionsupporting

confidence: 93%

Influence of Artificial Tears on Keratometric Measurements in Cataract Patients

Röggla

Leydolt

Schartmüller

et al. 2021

American Journal of Ophthalmology

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“…Moreover, the short-term influence of therapeutic eye drops for dry eye and glaucoma has been quantified by measuring the time course of HOAs or light scattering in healthy subjects. [66][67][68][69] These studies demonstrated that a temporal decrease in optical quality after the instillation of viscous ophthalmic solution or gel-forming solution may be primarily attributed to an increase in HOAs that is possibly caused by increased corneal irregularities. Furthermore, a temporal decrease in optical quality after the instillation of ophthalmic suspension may be primarily attributed to increased light scattering that is possibly caused by white particles.…”

Section: Accommodationmentioning

confidence: 93%

Overview of Objective Methods for Assessing Dynamic Changes in Optical Quality

Koh

Higashiura

Maeda

2016

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

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Quality of vision has been emphasized in ophthalmologic clinical practice in recent years. The optical or visual performance of the human eye is not static and fluctuates over time. Considering the major origins of temporal fluctuations in optical or visual performance, quantitative assessment of the dynamic changes in the optical quality of the entire eye is important. This review provides an overview of the clinical application of the objective methods for assessing dynamic changes in optical quality, particularly those associated with accommodation, the precorneal tear film, the prelens tear film, and contact lens movement and fitting.

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“…Accordingly, wavefront aberrometry is an essential and objective approach to detect the deterioration of optical quality [ 12 ]. Several studies using corneal topography [ 2 , 13 , 14 ] and Hartmann-Shack wavefront aberrometer [ 15 – 17 ] shed valuable light on the optical quality changes for dry eye cases.…”

Section: Introductionmentioning

confidence: 99%

Changes of Corneal Wavefront Aberrations in Dry Eye Patients after Treatment with Artificial Lubricant Drops

Lü

Lin

Zhu

et al. 2016

Journal of Ophthalmology

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Purpose. To evaluate the corneal aberration changes in dry eye patients after treatment with artificial eye drops. Methods. Thirty mild to moderate dry eye patients treated with artificial eye drops and twenty comparable dry eye patients were recruited as controls. Anterior corneal aberrations over 3 mm and 5 mm analytical zones including total, 3rd to 5th high order aberrations (HOAs), spherical aberration (SA), and vertical (V-coma) and horizontal coma (H-coma) obtained from corneal topography data at baseline and 2 weeks after treatment were evaluated. Results. For 3 mm zone, trefoils, V-coma, H-coma terms, and 3rd and 5th HOAs were significantly decreased (p < 0.05) in the treatment group. For 5 mm zone, instillation of eye drops reduced H-coma, SA terms, 3rd to 5th orders, and total HOAs all showed a significant decrease (p < 0.05). The root mean square analysis of the Zernike terms also showed similar statistical results. For control group, all individual terms and total HOAs did not have significant changes over 3 mm and 5 mm zones (p > 0.05). Conclusions. Treatment with artificial eye drops can effectively improve the corneal optical quality of dry eye patients by ameliorating the HOAs of anterior corneal surface.

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Time Course of Changes in Ocular Aberrations After Instillation of Carteolol Long-Acting Solution and Timolol Gel-Forming Solution

Abstract: Both topical β blockers with a once-daily dosing regimen temporarily deteriorate optical quality of the eye by increasing higher-order aberrations, and the increases are much larger after instillation of timolol gel than long-acting carteolol.

Cited by 9 publications

References 28 publications

Influence of Artificial Tears on Keratometric Measurements in Cataract Patients

Influence of Artificial Tears on Keratometric Measurements in Cataract Patients

Overview of Objective Methods for Assessing Dynamic Changes in Optical Quality

Changes of Corneal Wavefront Aberrations in Dry Eye Patients after Treatment with Artificial Lubricant Drops

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