TiF4 and NaF at pH 1.2 but not at pH 3.5 are able to reduce dentin erosion

Wiegand, Annette; Magalhães, Ana Carolina; Sener, Beatrice; Waldheim, Elena; Attin, Thomas

doi:10.1016/j.archoralbio.2009.05.004

Cited by 29 publications

(41 citation statements)

References 34 publications

(40 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…EDXRF has been used in several studies to evaluate the content of certain substances on the tooth surface. Wiegand et al (17) used this method to determine the amount of titanium (Ti) and fluoride (F) in the dentin surface of bovine specimens in a study that assessed the ability of some fluoridated compounds to reduce tooth erosion.…”

Section: Discussionmentioning

confidence: 99%

In Vitro assessment of dentin erosion after immersion in acidic beverages: surface profile analysis and energy-dispersive X-ray fluorescence spectrometry study

et al. 2012

View full text Add to dashboard Cite

The aim of this study was to investigate the effects of some acidic drinks on dentin erosion, using methods of surface profile (SP) analysis and energy-dispersive X-ray fluorescence spectrometry (EDXRF). One hundred standardized dentin slabs obtained from bovine incisor roots were used. Dentin slabs measuring 5x5 mm were ground flat, polished and half of each specimen surface was protected with nail polish. For 60 min, the dentin surfaces were immersed in 50 mL of 5 different drinks (Gatorade®, Del Valle Mais orange juice®, Coca-Cola®, Red Bull® and white wine), 20 blocks in each drink. The pH of each beverage was measured. After the erosive challenge, the nail polish was removed and SP was analyzed. The mineral concentration of dentin surfaces was determined by means of EDXRF. Data were analyzed statistically by ANOVA and Tukey's test (α=0.05). SP analysis showed that Red-Bull had the highest erosive potential (p<0.05). EDXRF results exhibited a decrease in phosphate in the groups immersed in Red-Bull, orange juice and white wine (p<0.05), and no significant difference in calcium content between the reference surface and eroded surface. In conclusion, this study demonstrated that all studied beverages promoted erosion on root dentin and Red Bull had the highest erosive potential. There was no correlation between pH of beverages and their erosive potential and only the P content changed after erosive challenge.

show abstract

Section: Discussionmentioning

confidence: 99%

In Vitro assessment of dentin erosion after immersion in acidic beverages: surface profile analysis and energy-dispersive X-ray fluorescence spectrometry study

et al. 2012

View full text Add to dashboard Cite

show abstract

“…It was decided to apply TiF 4 gel (2), because it would be an easy form to be used by the dentist and a comfortable presentation for the patient, since it can be rapidly applied and has no unpleasant taste. The native pH was used because of the efficiency demonstrated in other studies concerning the precipitate formation and demineralization reduction (9). The concentration of 4% obtained better results compared to lower concentrations, possibly due to its capability of forming a thicker and tenacious glaze after treatment (18).…”

Section: Discussionmentioning

confidence: 99%

“…These favorable properties of TiF 4 are, however, dependent on the concentration, pH and presentation form used for application (2,9). As there is still no consensus on the ideal formulation, the manipulated product used in this study was determined by the feasibility and probability of its clinical use in the future.…”

Section: Discussionmentioning

confidence: 99%

“…TiF 4 has a peculiar mechanism of action and a significant potential in reducing erosion progression (3), however, there is still no consensus on the ideal formulation for this fluoride's clinical use (2,9). The present study investigated the possible anti-erosive effects produced by 4% TiF 4 gel, under in situ conditions, with a simulated high incidence of erosive/abrasive episodes.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The In Situ Effect of Titanium Tetrafluoride Gel on Erosion/Abrasion Progression in Human Dentin

et al. 2017

View full text Add to dashboard Cite

Erosion incidence is increasing and its control is still a challenge in clinical practice. This study evaluated 4% TiF 4 -gel effects on eroded human dentin subjected to in situ erosive/ abrasive episodes. Seventy-two previously eroded dentin slabs (0.05 M citric acid, pH 2.3, 20 min) were allocated to 6 groups (n=12) according to the treatment to be performed during the in situ phase and number of erosive/abrasive cycles, as follows: 4% TiF 4 -gel applied once (TiF 4 1), twice (TiF 4 2) or three times (TiF 4 3) followed by 1, 2 and 3 erosive/ abrasive cycles, respectively. Gel was applied before the beginning of the next cycle. Control groups were subjected to 1 (C1), 2 (C2) and 3 (C3) erosive/abrasive cycles only. A seventh group (n=12) comprised in vitro uneroded samples (UN) subjected to 3 erosive/ abrasive cycles. Each cycle corresponded to 2 days of erosive (citric acid 0.5%, pH 2.6, 6x/day) and abrasive (electric toothbrush, 10 s/sample, 1 x/day) challenges. Samples were evaluated under profilometry and environmental scanning electron microscopy (ESEM). Atomic force microscopy images (AFM) were also made (n=3). Repeated measures 2-way ANOVA and Tukey test (p<0.001) showed that TiF 4 2, which did not differ from TiF 4 1 and TiF 4 3, revealed a significant reduction in surface loss compared to all control groups. TiF 4 1 and TiF 4 3 showed no significant difference from C1, but both groups demonstrated significantly smaller surface loss than C2 and C3. ESEM and AFM micrographs suggested alterations on treated surfaces compared to samples from control groups, showing reduced diameters of dentinal tubules lumens. Therefore, TiF 4 was able to reduce the progression of erosive/abrasive lesions.

show abstract

“…The electrostatic interaction between TiF 4 and acquired film proteins 36 and the presence of organic matrix on the dental surface 37 are capable of positively influencing the incorporation of fluoride by dental tissue 34 . Besides, the formation of an acid-resistant layer occurs on the dental surface 28,29,31,38 , which resembles to a glaze, and is ultrastructurally composed of numerous spherical particles 31,39 . Due to the high affinity between titanium ions and oxygen atoms, the titanium, once released by the hydrolysis of TiF 4 molecules, can bind to oxygen derived from water or phosphate molecules on the dental surface.…”

Section: Titanium Tetrafluoridementioning

confidence: 99%

Titanium Tetrafluoride (TiF4) in the Treatment of Dental Erosion

Mantilla

Freitas

2018

J. Health Scie.

View full text Add to dashboard Cite

Dental erosion is a multifactorial pathology that leads to dental substrate loss caused by its exposure to acids of non-bacterial origin. The process begins with a superficial demineralization of enamel, which, when continuously exposed to erosive solutions, can even lead to dentin exposure, causing aesthetic/functional problems to patients, besides increasing the chances of dentin hypersensitivity. Fluoride ResumoA erosão dental é uma patologia multifatorial que leva a uma perda de substrato dental causada pela sua exposição a ácidos de origem não-bacteriana. O processo se inicia com uma desmineralização superficial do esmalte, que, quando da continua exposição a soluções erosivas, pode levar a exposição do esmalte, causando problemas estéticos/funcionais aos pacientes, além de aumentar a chance de hipersensibilidade dentinária. Os produtos fluoretados, quando aplicados sobre a superfície dental, formam uma barreira física de proteção, que também pode agir como reservatório de íons F. Entretanto, frente a recorrentes desafios erosivos, esta proteção tem efetividade limitada. A literatura recente já demonstrou a capacidade de compostos contendo cátions metálicos polivalentes associados a fluoretos, incluindo o tetrafluoreto de titânio (TiF 4 ), para formar camadas mais ácido-resistentes. A capacidade do íon titânio de se ligar simultaneamente aos íons F e ao tecido dental permite a formação de uma barreira de difusão na superfície dental, conhecida como glaze, que a protege contra desmineralização ácida. Entretanto, ainda é necessário estabelecer um protocolo clínico ideal envolvendo a definição de fatores capazes de determinar o sucesso do tratamento, como concentração, pH, veículo e forma/tempo de aplicação, além da frequência para reaplicação. A presente revisão crítica tem como objetivo proporcionar uma breve visão geral dos mecanismos de ação do TiF 4 e discutir os fatores que podem melhorar sua capacidade protetora contra a erosão dental.Palavras-chave: Erosão Dentária. Flúor. Titânio.

show abstract

TiF4 and NaF at pH 1.2 but not at pH 3.5 are able to reduce dentin erosion

Cited by 29 publications

References 34 publications

In Vitro assessment of dentin erosion after immersion in acidic beverages: surface profile analysis and energy-dispersive X-ray fluorescence spectrometry study

In Vitro assessment of dentin erosion after immersion in acidic beverages: surface profile analysis and energy-dispersive X-ray fluorescence spectrometry study

The In Situ Effect of Titanium Tetrafluoride Gel on Erosion/Abrasion Progression in Human Dentin

Titanium Tetrafluoride (TiF4) in the Treatment of Dental Erosion

Contact Info

Product

Resources

About