Thyroid hormones, blood glucose and glycosylated hemoglobin in healthy Sudanese subjects

Eisa, Abdelmuhsin H.; Bashir, Amir; Osman, Asim Alaaeldin; Ali, Ibrahim; Awad, Kamal; Hajo, Elnagi Y.; Taha, Elmutaz H.; Alborai, Abeadalla A.; Musa, Omer A

doi:10.18203/2349-3933.ijam20192254

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…Similar results were reported by Kumar and co-workers (24), who found that the mean total cholesterol and LDL levels were elevated in hypothyroidism patients compared to controls. Thyroid dysfunction is highly common in patients with a longer duration of diabetes, and poor glycemic control and is associated with substantially higher serum cholesterol and triglyceride levels (25). The result of correlation showed that there was a significant association between Glucose and Arginase.…”

Section: Resultsmentioning

confidence: 99%

Study of arginase activity in serum of patients with hypothyroidism and type 2 diabetes mellitus

Abdand

Abbas

Abed

2022

ijhs

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In L-arginine metabolizing pathways, arginase and nitric oxide synthase are regulated in a reciprocal manner. In recent years, nitric oxide has been proposed as a key player in hyperthyroidism. The importance of arginase in arginine control has not yet been studied in hypothyroidism. The goal of this study was to examine the activity of arginase in in type 2 diabetic patients with and without hypothyroidism. The two most popular endocrinopathies that exist in clinical practice are thyroid disease and diabetes mellitus DM. The thyroid hormones, on the other hand, control the metabolism of carbohydrates and the pancreas activity. The study group consisted of 120 subjects divided into four groups; the first group included 30 healthy control subjects, the second group included 30 patients with both hypothyroidism and type 2 DM, the third group included 30 patients with hypothyroidism without type 2 diabetes (T2DM) and the fourth group included 30 patients with T2DM without hypothyroidism. The concentration of fasting serum glucose (FSG), total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL), low density lipoprotein (LDL), very low-density lipoprotein (VLDL), triiodothyronine (T3), thyroxin (T4), thyroid-stimulating hormone (TSH) were determined.

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Section: Resultsmentioning

confidence: 99%

Study of arginase activity in serum of patients with hypothyroidism and type 2 diabetes mellitus

Abdand

Abbas

Abed

2022

ijhs

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“…18 A Similar results were observed in the study conducted by Raghuwansh K et al 14 The study shows a affirmative co-relation between HbA 1 C and TSH and it was highly statistically significant and negative correlation between HbA 1 C and T 3 which was statistically significant and positive correlation between HbA 1 C and T 4 and was statistically non significant. Altered glucose homeostasis with reduced absorption and decreased utilization of glucose are related with hyper insulinemia and insulin resistance probably causing transient elevations in the glucose concentrations consequently contributing to glycation of serum proteinwhich was observed by Asmabi et al and Tarig et al 17,19…”

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confidence: 94%

Correlation of T3, T4, TSH with fasting plasma glucose and glycosylated haemoglobin in patients of type 2 diabetes mellitus

Kaur¹,

Kaur²,

Kaur³

et al. 2020

IJCBR

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The two most common endocrine disorders encountered in clinical practice are Thyroid diseases and Diabetes Mellitus. Diabetes and thyroid disorders have been shown to reciprocally influence each other and an association between both conditions are generally reported. Thyroid disease is a hazardous condition as it can lead to uncontrolled glycemic control in diabetic patients. Thyroid disease is found usually in diabetes and is associated with advanced age, particularly in type 2 diabetes. The aim of the present study was to correlate Fasting plasma glucose (FPG) with Thyroid hormones levels and to correlate Glycosylated Hemoglobin levels (HbA 1 C) with thyroid hormones. The present hospital -based cross sectional study was conducted on sample size of 200 subjects of age more than 40 years. These subjects were divided into two groups-100 known Type 2 Diabetes Mellitus constituting study group and 100 healthy age and gender matched individuals constituting control group. The thyroid hormones were analyzed with the ELISA method and HbA1C was analyzed using Ion Exchange Resin Method. The results of the present study showed a positive correlation between TSH and FPG, HbA1C with TSH, a negative correlation of HbA1C with T 3 and there was a negative correlation between FPG and T 3 .

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Thyroid hormones, blood glucose and glycosylated hemoglobin in healthy Sudanese subjects

Cited by 2 publications

References 17 publications

Study of arginase activity in serum of patients with hypothyroidism and type 2 diabetes mellitus

Study of arginase activity in serum of patients with hypothyroidism and type 2 diabetes mellitus

Correlation of T3, T4, TSH with fasting plasma glucose and glycosylated haemoglobin in patients of type 2 diabetes mellitus

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