Thyroid Cancer–Specific Quality of Life and Health-Related Quality of Life in Young Adult Thyroid Cancer Survivors

Abstract

TC-specific QOL is significantly influenced by many socio-demographic and clinical factors. HRQOL is lower in female YA TC survivors compared with the normal age-matched population. Neuromuscular, concentration, and anxiety complaints had the greatest impact on HRQOL in YA TC survivors.

Age‐related differences in health‐related quality of life among thyroid cancer survivors compared with a normative sample: Results from the PROFILES Registry

“…10 That study found that adolescents and young adult thyroid cancer survivors (17-39 years) reported significantly less neuromuscular, voice, sympathetic, and throat/mouth complaints than older (40 years) survivors. Results showed that adolescents and young adult thyroid cancer survivors scored statistically significant and clinically meaningfully better on physical functioning compared with the elderly.…”

“…[6][7][8][9] A systematic review on HR-QOL among thyroid cancer survivors showed mixed results; thyroid cancer survivors, in general, have either a similar or a worse HR-QOL compared with the normative sample, and survivors reported specific medical problems that were associated with poorer HR-QOL. 10 The purposes of our exploratory population-based crosssectional study were to compare general HR-QOL of thyroid cancer survivors with an age-matched and sex-matched normative sample stratified by age categories (ie, adolescents and young adults [18-35 years], middle-aged adults [36-64 years], and the elderly [65-84 years]) in order to determine whether differences in HR-QOL are associated with cancer and its treatment or with age. According to a large-scale study (n 5 1174), female sex, young age at diagnosis, and a lower educational level were highly predictive of a decreased HR-QOL.…”

Minimally invasive and remote‐access thyroid surgery in the era of the 2015 American Thyroid Association guidelines

“…Ryu et al in Korea demonstrated improvement in patient satisfaction with final cosmesis following robotic thyroidectomy when compared to conventional approach . Quality‐of‐life studies continue to demonstrate that the cervical incision can be burdensome …”

Is it time to reconsider lobectomy in low‐risk paediatric thyroid cancer?

“…Thyroid lobectomy is associated with a lower risk of surgical complications including recurrent laryngeal nerve palsy and (transient) hypoparathyroidism . Moreover, most patients who undergo less‐than‐total thyroidectomy retain autonomous thyroid function, making it easier to achieve a euthyroid state in these patients and potentially avoiding negative impact on quality of life associated with total thyroidectomy and lifelong thyroid replacement . Nonetheless, a subset of children undergoing lobectomy may still require levothyroxine treatment to achieve adequate TSH suppression.…”