Thyroid Cancer in Western Algeria: Histopathological and Epidemiological Study

Abstract

Thyroid cancer is relatively rare, about 1% of all cancers combined. However, it accounts for 88% of all cancers of the endocrine organs. In recent years, the incidence of thyroid cancer has increased considerably compared to other types of endocrine cancers. The aim of our work is to study the epidemiological profile of thyroid cancer in the western part of Algeria and to determine the influence of sex, age and histological type. Patients and methods: Our study focuses on 1376 cases of thyroid cancer in patients attending the nuclear medicine department at the university hospital of Tlemcen over a period of 3 years, from 2013 to 2015. The average age of patients is estimated at 43. Each patient underwent an anatomo-histopathological examination of the surgical specimen. The data entry is done through the SPSS 20 statistical software. Results: The rates of the thyroid cancers listed during the three years of studies (2013-2014-2015) are 32.12%, 34.44% and 33.43% respectively. Our study shows that the female sex is largely incriminated (94.75%) compared to the male sex. The age group mostly affected was that ranging from 40 to 60 with 45.88%. The anatomo-histopathological analysis revealed that the papillary carcinoma is the most frequent histological type with 85.47% followed by the vesicular carcinoma with 14%, the medullary cancer MTC with 0.43%, and finally the anaplastic carcinoma with 0.07%. Conclusion: the epidemiological surveillance contributes to a better knowledge of thyroid carcinoma allowing a good patient management in Algeria. Early detection of small size cancers and the use of high-performing technologies will result in a decrease of the mortality rate associated to this type of cancer.

Decline in radioiodine use but not total thyroidectomy in thyroid cancer patients treated in the United Arab Emirates - A retrospective study

“…Follicular TC was found in 4.6% of the patients while anaplastic and medullary cancers were rare. These findings are consistent with studies from the MENA region as well as other parts of the world [ [3] , [4] , [5] , [6] , [7] , [8] , [9] ]. The mean age at diagnosis of TC in our study was 39.7 years which is lower compared to the age of 44.7 years from a large retrospective study of 12, 508 TC patients diagnosed between 1972 and 2014 from 8 cancer registries in southeast china [ 19 ].…”

“…Management of thyroid cancer (TC) has significantly changed in the last decade with several guidelines advocating for a conservative approach in the majority of patients [ 1 , 2 ]. While these changes resulted in lower rates of total thyroidectomy and radioiodine administration in some parts of the world [ 3 , 4 ], data on TC from the Middle East and North Africa (MENA) region has largely focused on incidence, characteristics, and treatment outcomes with recent exploration of TC genetics [ [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] ]. Little is known about the trend in TC management in this region.…”

Copper Isotopes and Copper to Zinc Ratio as Possible Biomarkers for Thyroid Cancer

“…It is diagnosed three times more in woman (10.2 per 100,000) than in men (3.1 per 100,000) ( 4 ). In Algeria, thyroid cancer incidence is increasing, taking now the 3rd place in women after breast and colorectal cancer, while in 2006 it occupied the 5th position in frequency ( 5 , 6 ). Four types of thyroid cancer are histologically distinguished.…”

Histopathological Characteristics and Incidence of Thyroid Carcinoma in a Tertiary Care Hospital of Pakistan - A retrospective study

“…Thyroid cancer is somewhat infrequent, almost 1% of all malignancies combined. However, it is the most frequently occurring cancer (up to 88%) of endocrine organs 1 . From the past few decades, the prevalence of thyroid carcinoma is increasing generally and this has aroused the great public concern 2 .…”