Three generations of selection for high and low donor competences of splenomegaly in chickens<sup>1</sup>

Okada, Ikuo; Mikami, Hitoshi

doi:10.1080/00071667408416076

Cited by 26 publications

(8 citation statements)

References 18 publications

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“…Bacon and Craig (1966; and Gilmour (1967) found a histocompatibility gene on the W chromosome by skin grafting or wattle grafting. Okada and Mikami (1974) also suggested the existence of sex-linked genes in the GvH reaction. Present results, while suggesting the participation of sex-linked gene (s) in the GvH response, reveal the influence of sex-linked gene (s) to be less than that of the B locus.…”

Section: Resultsmentioning

confidence: 94%

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The Quantitative Effects of the B Blood Group Locus and Sex Linked Histocompatibility Antigen in Chickens on G-v-H Reaction

Yamamoto

1981

Poultry Science

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The major histocompatibility locus in the chicken is the B locus with a minor histocompatibility antigen controlled by a gene (s) on the W chromosome. This study was designed to determine the quantitative effects of the B locus and the sex linked histocompatibility gene on splenomegaly of chick embryos after inoculation with adult male lymphocytes. The embryos and male lymphocyte donors had blood group genotypes designed B9/B9, B9/B11 so that nine donor-host combinations were used. When the donor and host were homozygous for different B alleles (B9 and B11) or different by one B allele (B9 or B11) the splenomegaly was 4 and 2 times greater, respectively, than the compatible donor and host. A greater splenomegaly was produced in male to female injections than in male to male injections. However, the histocompatibility antigen controlled by a gene(s) on the W chromosome was weaker than the controlled by the B locus.

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Section: Resultsmentioning

confidence: 94%

“…The nomenclature of B alleles used in the present study was given be Okada and Mikami (1974). This nomenclature is not the same as that of Briles et al (1950Briles et al ( , 1957.…”

Section: Methodsmentioning

confidence: 89%

The Quantitative Effects of the B Blood Group Locus and Sex Linked Histocompatibility Antigen in Chickens on G-v-H Reaction

Yamamoto

1981

Poultry Science

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“…After four generations of selection, the lines have been maintained by random mating. The details of the lines were described previously by Okada & Mikami (1974).…”

Section: Experimental Birdsmentioning

confidence: 99%

“…The details of the methods had been previously presented by Matsumoto & Okada (1961). The nomenclature of the B alleles used in the present paper had been given by Okada & Mikami (1974) and is not necessarily the same as that of Briles et al (1950Briles et al ( , 1957. Two B alleles, B9 and B", segregated in both H and L lines.…”

Section: Blood Group Typingmentioning

confidence: 99%

“…Similar results were also found by Giinther et al (1974), Pevzner et al (1975) and Benedict et al (1975). Okada & Mikami (1974) selected chickens for high and low donor competences of GVHR and established two lines having different GVHR competences (Okabayashi & Okada, 1976). The present work intends to examine whether the immune responsiveness between the two GVHR-selected lines and between birds having different B locus genotypes differs or not.…”

Section: Introductionmentioning

confidence: 99%

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Genetic control of the immune response in lines of chickens selected for graft‐versus‐host competences

Okabayashi

Okada

1977

Animal Blood Groups and Biochemical Genetics

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The immune response of chickens to goat erythrocytes has been examined. The H line selected for high competence of graft-versus-host reaction (GVHR) showed higher immune responses than the L line selected for low GVHR competence. It appeared also that immune responses were controlled by the B blood group locus, which is the major histocompatibility locus in chickens. The relative immune responsiveness of B genotypes were B l l / l l > B9/B1l > B8/Bg. Treatment of antiserum with 2-mercaptoethanol (2-ME) proved that the difference in immune responses between lines was due mainly to the 2-ME resistant antibody and that the difference between the B genotypes was due to the 2-ME sensitive antibody.

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The Major Histocompatibility System of the Chicken

Hála¹

1977

The Major Histocompatibility System in Man and Animals

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Three generations of selection for high and low donor competences of splenomegaly in chickens¹

Cited by 26 publications

References 18 publications

The Quantitative Effects of the B Blood Group Locus and Sex Linked Histocompatibility Antigen in Chickens on G-v-H Reaction

The Quantitative Effects of the B Blood Group Locus and Sex Linked Histocompatibility Antigen in Chickens on G-v-H Reaction

Genetic control of the immune response in lines of chickens selected for graft‐versus‐host competences

The Major Histocompatibility System of the Chicken

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Three generations of selection for high and low donor competences of splenomegaly in chickens1

Cited by 26 publications

References 18 publications

The Quantitative Effects of the B Blood Group Locus and Sex Linked Histocompatibility Antigen in Chickens on G-v-H Reaction

The Quantitative Effects of the B Blood Group Locus and Sex Linked Histocompatibility Antigen in Chickens on G-v-H Reaction

Genetic control of the immune response in lines of chickens selected for graft‐versus‐host competences

The Major Histocompatibility System of the Chicken

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Product

Resources

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Three generations of selection for high and low donor competences of splenomegaly in chickens¹