Three-dimensional flow velocity and wall shear stress distribution measurement on a micropillar-arrayed surface using astigmatism PTV to understand the influence of microstructures on the flow field

Ichikawa, Y.; Yamamoto, Ken; Motosuke, Masahiro

doi:10.1007/s10404-018-2095-8

Cited by 14 publications

(11 citation statements)

References 46 publications

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“…Following this approach, researchers have investigated grooves 16,17 or herringbone structures 18,19 to improve performance. Channels containing obstacles 20,21 or micropillars 22,23 have also been used to control the shape of streams. Depending on the pattern of the pillar, these channels are capable of focusing particles at an arbitrary width of the channel.…”

Section: Introductionmentioning

confidence: 99%

New insights into the physics of inertial microfluidics in curved microchannels. II. Adding an additive rule to understand complex cross-sections

et al. 2019

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Curved microchannels allow controllable microparticle focusing, but a full understanding of particle behavior has been limited-even for simple rectangular and trapezoidal shapes. At present, most microfluidic particle separation literature is dedicated to adding "internal" complexity (via sheath flow or obstructions) to relatively simple cross-sectional channel shapes. We propose that, with sufficient understanding of particle behavior, an equally viable pathway for microparticle focusing could utilize complex "external" cross-sectional shapes. By investigating three novel, complex spiral microchannels, we have found that it is possible to passively focus (6, 10, and 13 μm) microparticles in the middle of a convex channel. Also, we found that in concave and jagged channel designs, it is possible to create multiple, tight focusing bands. In addition to these performance benefits, we report an "additive rule" herein, which states that complex channels can be considered as multiple, independent, simple cross-sectional shapes. We show with experimental and numerical analysis that this new additive rule can accurately predict particle behavior in complex cross-sectional shaped channels and that it can help to extract general inertial focusing tendencies for suspended particles in curved channels. Overall, this work provides simple, yet reliable, guidelines for the design of advanced curved microchannel cross sections.

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Section: Introductionmentioning

confidence: 99%

New insights into the physics of inertial microfluidics in curved microchannels. II. Adding an additive rule to understand complex cross-sections

et al. 2019

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“…By far, the most widely used technique for 3D point localization is astigmatic imaging, as evidenced by the wealth of literature which use this method: from micro-PTV [69][70][71][72] to super-resolution microscopy [73][74][75][76] (Fig. 4).…”

Section: Early Methods Of Psf Engineeringmentioning

confidence: 99%

Advances in 3D single particle localization microscopy

et al. 2019

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The spatial resolution of conventional optical microscopy is limited by diffraction to transverse and axial resolutions of about 250 nm, but localization of point sources, such as single molecules or fluorescent beads, can be achieved with a precision of 10 nm or better in each direction. Traditional approaches to localization microscopy in two dimensions enable high precision only for a thin in-focus layer that is typically much less than the depth of a cell. This precludes, for example, super-resolution microscopy of extended three-dimensional biological structures or mapping of blood velocity throughout a useful depth of vasculature. Several techniques have been reported recently for localization microscopy in three dimensions over an extended depth range. We describe the principles of operation and typical applications of the most promising 3D localization microscopy techniques and provide a comparison of the attainable precision for each technique in terms of the Cramér-Rao lower bound for high-resolution imaging.

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“…Надо отметить, что изучению течений в каналах, содержащих массив цилиндров, посвящено значительное количество работ, мотивированных решением различных практических задач с использованием технологий " лаборатория на чипе", жидкостной хроматографии, теплопереноса и др. [13][14][15][16]. Главным образом, в этих работах изучаются установившиеся однофазные течения после затекания жидкости в систему цилиндров.…”

Section: Introductionunclassified

Изучение Особенностей Пропитки Сред С Двумя Масштабами Пористости

Батыршин¹,

Солнышкина²,

Питюк³

2021

Журнал Технической Физики

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The trapping of bubbles during the impregnation of micromodel of dual scale porisity media by a liquid are experimentally studied. The micromodel of a porous medium is formed by a system of cylindrical pins spatially ordered in a flat microchannel. It is shown that the content of bubbles in a porous medium after impregnation depends on the capillary number and wettability of the pore surface. The proposed approach can be used to solve the practically important problem on studying and selecting optimal mechanisms to control the impregnation process of porous materials to minimize the total amount of trapped bubbles.

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Three-dimensional flow velocity and wall shear stress distribution measurement on a micropillar-arrayed surface using astigmatism PTV to understand the influence of microstructures on the flow field

Cited by 14 publications

References 46 publications

New insights into the physics of inertial microfluidics in curved microchannels. II. Adding an additive rule to understand complex cross-sections

New insights into the physics of inertial microfluidics in curved microchannels. II. Adding an additive rule to understand complex cross-sections

Advances in 3D single particle localization microscopy

Изучение Особенностей Пропитки Сред С Двумя Масштабами Пористости

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