Thermodynamic mechanism of particulation of sodium alginate and chitosan polyelectrolyte complexes as a function of charge ratio and order of addition

Yılmaz, Tuncay; Maldonado, L.; Turasan, Hazal; Kokini, Jozef L.

doi:10.1016/j.jfoodeng.2019.03.002

Cited by 39 publications

(23 citation statements)

References 27 publications

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“…To understand the thermodynamics of nanoparticulation of oppositely charged polyelectrolytes sodium alginate and chitosan in detail, isothermal titration calorimetry was conducted (Yilmaz, Maldonado, Turasan, & Kokini, ). The zeta potentials of sodium alginate and chitosan were shown to enable maximum electrostatic interaction between chitosan and sodium alginate at pH 4 (Figure ).…”

Section: Coacervationmentioning

confidence: 99%

“…Zeta potential of chitosan (▲) and sodium alginate (●) as a function of pH. Reprinted from Yilmaz et al () with permissions from Elsevier…”

Section: Coacervationmentioning

confidence: 99%

“…Thermodynamics of interaction were studied as a function of the order of addition, sodium alginate into chitosan or chitosan into sodium alginate, and molar charge ratios (Yilmaz et al, ). The overall enthalpy of polyelectrolyte complex formation was −3,207 kJ/mol when sodium alginate was added into chitosan, and −1,683 kJ/mol when chitosan was added into sodium alginate, suggesting a stronger interaction between the polyelectrolytes when sodium alginate was added to chitosan.…”

Section: Coacervationmentioning

confidence: 99%

“…Bottom graph (b), blue: Alg/Chi–ζ (mV), orange: Chi/Alg–ζ (mV), gray: Alg/Chi–Q (μJ), yellow: Chi/Alg–Q (μJ). Reprinted from Yilmaz et al () with permissions from Elsevier…”

Section: Coacervationmentioning

confidence: 99%

“…A saturation point is reached after 14 injections, after which an endothermic reaction followed. The exothermic reactions are associated with the non‐specific electrostatic interaction between the opposite charged biopolymers, while the endothermic reactions suggest additional conformational rearrangements of the BSA and sodium alginate when saturation is reached (Yilmaz et al, ).…”

Section: Layer‐by‐layer (Lbl) Assemblymentioning

confidence: 99%

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Comparison of the fabrication methods, formation dynamics, structure, and delivery performance of solid nanoparticles and hollow layer‐by‐layer edible/biodegradable nanodelivery systems

Turasan

Bonilla

Bozkurt

et al. 2020

J Food Process Engineering

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Aim: This article summarizes and reviews recent studies on nanoparticulation of solid and hollow nanoparticles using edible proteins and carbohydrates from plant and animal origin and shares new research conducted in our laboratory on fabrication of biopolymer-based nanodelivery systems. Methods:We compare the properties of nanoparticles fabricated using desolvation, coacervation, and layer-by-layer assembly. The parameters affecting the morphological and physical states of the nanodelivery systems as well as their abilities to encapsulate bioactive compounds, and the mechanisms of the nanoparticulation process are discussed in detail. Results:The article offers methods that need to be used with each nanoparticulation technique along with key characterization data obtained. The effect of varying a wide range of parameters on particle size, size distribution, morphology, effect of solvents and non-solvents, effect of surface charge of polyelectrolytes, effect of fabrication conditions are presented. Conclusions:We believe the article gives enough detail to give the reader useful information related to the performance of all the different nanoparticles studied in our laboratory over the last 6 years.Practical applications: Biopolymer based nanodelivery systems presented in this article, have great potential to be used in the nutraceutical, food, pharmaceutical industries as well as agriculture. The biodegradable and edible nature of these nanodelivery systems make them safe for incorporating into food and nutraceutical materials, because, the biopolymers used in their fabrication are biocompatible polymers of food origin that are generally recognized as safe (GRAS) (Food and Drug Administration, The Daily Journal of the United States Government, 2016). Therefore, use of edible polymer-based nanoparticles would be safer and less toxic and consequently better for all these industries. For example, in the food industry, antioxidant compounds can be encapsulated which would then be incorporated into packaging materials and that would help maintain freshness and good quality and would prevent oxidative deterioration of foods to increase shelf life. Pesticides and insecticides can also be encapsulated in these

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Section: Coacervationmentioning

confidence: 99%

“…Zeta potential of chitosan (▲) and sodium alginate (●) as a function of pH. Reprinted from Yilmaz et al () with permissions from Elsevier…”

Section: Coacervationmentioning

confidence: 99%

Section: Coacervationmentioning

confidence: 99%

“…Bottom graph (b), blue: Alg/Chi–ζ (mV), orange: Chi/Alg–ζ (mV), gray: Alg/Chi–Q (μJ), yellow: Chi/Alg–Q (μJ). Reprinted from Yilmaz et al () with permissions from Elsevier…”

Section: Coacervationmentioning

confidence: 99%

Section: Layer‐by‐layer (Lbl) Assemblymentioning

confidence: 99%

See 3 more Smart Citations

Comparison of the fabrication methods, formation dynamics, structure, and delivery performance of solid nanoparticles and hollow layer‐by‐layer edible/biodegradable nanodelivery systems

Turasan

Bonilla

Bozkurt

et al. 2020

J Food Process Engineering

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Green and Scalable Biopolymer‐Based Aqueous Polyelectrolyte Complexes for Zinc‐Ion Charge Storage Devices

Fernández‐Benito,

Martinez‐López,

Javad Jafari

et al. 2023

ChemElectroChem

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Green and scalable materials are essential to fulfill the need of electrification for transitioning into a fossil‐fuels free society, and sustainability is a requirement for all new technologies. Rechargeable batteries are one of the most important elements for electrification, enabling the transition to mobile electronics, electrical vehicles and grid storage. We here report synthesis and characterization of polyelectrolyte complexes of alginate and chitosan, both biopolymers deriving from the sea, for transport of zinc ions in hydrogel electrolytes. We have used vibrational spectroscopy, thermal measurements and microscopy, as well as transport measurements with ohmic or blocking contacts. The transference number for zinc ions is close to 1, the conductivity is ≈10 mS/cm, with stability at Zn interfaces seen through 7000 cycles in symmetric zinc//zinc cell.

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Ascorbic acid nanoencapsulation using polyelectrolyte complex formation and optimization using hybrid artificial neural network‐genetic algorithm

Khuntia,

Mitra

2023

JSFA Reports

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BackgroundsThe polyelectrolyte complex (PEC) formation using chitosan (Cs) and alginate (Alg) has been employed to carry out Vitamin C (VC) nanoencapsulation because of its instability in adverse conditions. This method includes VC nanoencapsulation using physical cross‐linking. The effect of the mixing order as well as the different mass ratios of both the polymer and the VC content, were investigated on the size, pdi, zeta potential, encapsulation efficiency (EE%), and yield%. Hence, considering different mass ratios of both polymer (4:1–1:4) and VC content (10%–30% w/w of Cs) as independent variables, PECs were formed using 0.1% (w/v) of Cs and Alg solution.ResultThe result showed that, for equal mass ratio (1:1) of Cs and Alg, the addition of Alg solution to Cs solution led to lower particle size, while higher particle size was observed with reverse order of addition. However, no significant effect of polymer mass ratios was observed on particle size and NPs stability, while EE varied with VC concentration. Artificial neural network (ANN) was applied to train the experimental parameters Cs: Alg ratios (X1:X2) and VC content (X3) for the output variables. Moreover, process optimization was carried out using multi‐objective genetic algorithm (MOGA) with the goal of lowering particle size and increasing EE while increasing nanoparticle yield.ConclusionThe PEC method effectively encapsulated VC as obtained from higher EE. The Cs: Alg ratio of 4:2.1 and 18% VC content (w/w of Cs) was found optimum for nanoencapsulation. The final ANN‐GA model showed an acceptable agreement with experimental data.

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Thermodynamic mechanism of particulation of sodium alginate and chitosan polyelectrolyte complexes as a function of charge ratio and order of addition

Cited by 39 publications

References 27 publications

Comparison of the fabrication methods, formation dynamics, structure, and delivery performance of solid nanoparticles and hollow layer‐by‐layer edible/biodegradable nanodelivery systems

Comparison of the fabrication methods, formation dynamics, structure, and delivery performance of solid nanoparticles and hollow layer‐by‐layer edible/biodegradable nanodelivery systems

Green and Scalable Biopolymer‐Based Aqueous Polyelectrolyte Complexes for Zinc‐Ion Charge Storage Devices

Ascorbic acid nanoencapsulation using polyelectrolyte complex formation and optimization using hybrid artificial neural network‐genetic algorithm

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