Ascorbic acid nanoencapsulation using polyelectrolyte complex formation and optimization using hybrid artificial neural network‐genetic algorithm
Anjali Khuntia,
Jayeeta Mitra
Abstract:BackgroundsThe polyelectrolyte complex (PEC) formation using chitosan (Cs) and alginate (Alg) has been employed to carry out Vitamin C (VC) nanoencapsulation because of its instability in adverse conditions. This method includes VC nanoencapsulation using physical cross‐linking. The effect of the mixing order as well as the different mass ratios of both the polymer and the VC content, were investigated on the size, pdi, zeta potential, encapsulation efficiency (EE%), and yield%. Hence, considering different ma… Show more
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