Therapeutic management of an extensive pressure ulcer affecting occipital and parietal bone-stem cell therapy

Abstract

A female patient of 89 years (born in 1927), in a good health condition, living on her own in a house suffered a stroke in 2001, and in 2010 she was diagnosed with an inoperable brain tumour (meningioma). Apart from occasional memory loss and short term nausea she had no difficulties and could take care of herself. Following a visit by her relatives in December 2013 she suddenly lost consciousness, collapsed, and was lying on a stone floor until her relatives found her after the following two days. She developed an extensive pressure ulcer on her shoulder blades and on the occipital and parietal bone on her skull, accompanied by loss of hair, skin, and subcutaneous tissue up to the bone in the extent of 10 x 12 cm. After two months of hospitalisation at the Department of Neurology her general condition stabilised, she could communicate, but her mobility was limited. The pressure ulcer on her shoulder blade healed quite effectively, the manifestations on the cranium were stagnant, the pressure ulcer showed callous margins, and the bone was coloured dark brown to black. Since March 2014 the therapy included gel preparations, In May 2014 we commenced therapy using stem cells-fibroblasts, on a culture medium-cellulose wound dressing Hcel ®