Therapeutic effect of two fluoride varnishes on white spot lesions: a randomized clinical trial

Ferreira, Jainara Maria Soares; Aragão, Ana Karla Ramalho de; Rosa, Adriana Dias Batista; Sampaio, Fábio Correia; Menezes, Valdenice Aparecida de

doi:10.1590/s1806-83242009000400015

Cited by 40 publications

(55 citation statements)

References 19 publications

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“…This finding corroborates those of previous studies (6,10,12,16,18,19). There was a 45.7% reduction in WSL size, which is in agreement with previous studies (9,10,12,16).…”

Section: Discussionsupporting

confidence: 93%

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Therapeutic potential of Brazilian fluoride varnishes: an in vivo study

et al. 2011

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The aim of this study was to assess in vivo the therapeutic effect of three fluoride varnishes available in the Brazilian market on the performance of white spot lesions (WSL). The sample included 36 children aged 7 to 13 years old, with a total of 67 active WSL in permanent anterior teeth. The children were randomly divided into 3 groups, according to fluoride varnish used: FL-Fluorniz (n=24), DUO -Duofluorid XII (n=22) and DF -Durafluor (n=21). Maximum WSL dimensions (mesiodistal and incisogingival) were measured in millimeters by a previously calibrated single examiner using a periodontal probe. WSL were also assessed regarding lesion activity. Initial and final S-OHI (Simplified Oral Hygiene Index) scores were recorded. Pearson's chi-square test revealed no statistically significant differences (p>0.05) in the performance of the varnishes. At the end of the 5th week, FL had 6 active and 18 inactive WSL; DUO had 7 active and 15 inactive WSL; and DL had 6 active and 15 inactive WSL. Taking into account all lesions, there was a 45.7% reduction in WSL dimensions. Paired Student's t-test revealed a statistically significant difference (p<0.05) between the initial size (1.88) and final size (1.02). After four applications, all varnishes obtained similar clinical results.

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“…This finding corroborates those of previous studies (6,10,12,16,18,19). There was a 45.7% reduction in WSL size, which is in agreement with previous studies (9,10,12,16).…”

Section: Discussionsupporting

confidence: 93%

“…Similar results were found in the in vivo and in vitro study carried out by Slade et al (20), comparing Fluorniz, Durafluor and Duofluorid was well as in the in vivo study carried out by Ferreira et al (16), who assessed Duraphat and Duofluorid XII fluoride varnishes.…”

Section: Discussionsupporting

confidence: 88%

Therapeutic potential of Brazilian fluoride varnishes: an in vivo study

et al. 2011

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“…This is an intervention study developed in the form of a randomized clinical trial according to the fluoride varnish applied that evaluated 60 children of both sexes aged from 06 months to 5 years assisted in the "Só-Riso" Project -Mother and Child Care, Dental School, Federal University excluded from the study [9]. Parents / guardians received guidance on practices favorable to the maintenance of oral health such as diet and oral hygiene, especially on brushing with small amount of fluoridated toothpaste twice a day.…”

Section: Methodsmentioning

confidence: 99%

“…Although the use of FV does not completely prevent the development of caries lesions, their reduced incidence and depth should be considered (1). Previous studies have demonstrated the possibility of stoppage of incipient lesions through their inactivation after the fourth FV application, thereby excluding the need for invasive restorative treatment [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

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Clinical Effectiveness of Two Commercial Fluoride Varnish Formulations on the Control of White Spot Lesion in Primary Teeth: A Pilot Study

Itaborahy¹,

Machado²,

Elias³

et al. 2015

Pesqui. bras. odontopediatria clín. integr.

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Objective: To evaluate the in vivo clinical effectiveness of two commercial fluoride varnish formulations. Material and Methods: The sample consisted of seven children aged 2-5 years for a total of 24 active white spot lesions (WSL) in primary teeth. Children were randomly divided into two groups in accordance with the varnish used: G1 -Duraphat® -DR (n = 14 WSL); and G2 -Duofluorid XII® -DF (n = 10 WSL). Children were submitted to treatment with varnishes applied once a week for four consecutive weeks. Maximum mesiodistal and incisogengival dimensions were measured with a periodontal probe at the beginning of treatment and on the fifth week of treatment. The average between the two dimensions represented the value of the WSL dimension. The comparison of the mean final values of WSL dimensions between groups of fluoride varnishes tested was analyzed by the Mann-Whitney U test. The significance level adopted was 5%. Results: After five weeks, most WSL were ranked as inactive (G1 = 71.4% and G2 = 40%). No significant difference between G1 and G2 in relation to lesion activity was observed (p = 0.124). There was a significant decrease of 24% between initial (3.12 mm ± 1.49 mm) and final WSL dimension (2.35 mm ± 1.06 mm) (p = 0.012) in G1. In G2, there was a significant reduction of 40% in lesion dimension with initial value of 5.7 mm (± 3.82 mm) and final value of 3.4 mm (± 3.35 mm) (p = 0.013). Regarding the reduction in the WSL dimension, no significant difference between groups was observed (p = 0.931). Conclusion: Both fluoride varnish formulations tested had similar effect on the control of active white spot lesions in primary teeth.

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