Thebaine Content of Selections of Papaver bracteatum Lindl. at Different Ages

Vincent, Phillip G.; Bare, Charles; Gentner, W. A.

doi:10.1002/jps.2600661215

Cited by 22 publications

(8 citation statements)

References 4 publications

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“…Several of the alkaloids earlier described from P. bracteaturn have been isolated and characterized in Russian material of the species Further studies of various strains of P. bracteaturn for theicr thebaine content in roots and aboveground portions during ontogenesis have been performed [112]. In selecting P. bracteaturn for high thebaine yield, total thebaine content should be considered rather than high thebaine concentrations in various parts.…”

Section: Addendummentioning

confidence: 99%

Papaver bracteatum – a Summary of Current Knowledge

Nyman

Bruhn

1979

Planta Med

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vestigated f o r 15 years, A review of recent investigations in the fields of Increasing abuse of opiates has made botany, genetics, cytology, biochemistry it necessary t o obtain alternative sour-and pharmacognosy is given in this sumces to Papaver somniferum as raw ma-mary. The closely related P. orientale terial for the pharmaceutical industry. and P. pseudo-orientale are briefly One suitable source is Papaver bractea-reviewed. Other alternative sources t o tum LINDL. which has been closely in-P. somniferum are also discussed. bracteaturn today is the series of papers published by the U.N. (United Nations. Division of Narcotic Drugs. "Scientific Research on Papaver bracteaturn." ST/

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Section: Addendummentioning

confidence: 99%

Papaver bracteatum – a Summary of Current Knowledge

Nyman

Bruhn

1979

Planta Med

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“…GLC Determination of Thebaine-Thebaine was determined quantitatively by GLC, and the results were corroborated by TLC and spectrophotometry a t 285 nm (6). Working limits for linear detector re- GLC flame-ionization responses to varying concentrations of thebaine uersus a constant level of cholesterol acetate were linear throughout the range analyzed.…”

Section: Results a N D Discussionmentioning

confidence: 80%

Papaver bracteatum Lindi.: Quantitative Extraction and Determination of Thebaine

Vincent

Gentner

Küppers

et al. 1979

Journal of Pharmaceutical Sciences

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“…Vincent et al . noted that the maximum thebaine content in the root of Arya I and Arya II accessions was about 11 and 7 mg/g of dry weight, respectively. Moreover, Meshulam and Lavie reported 1% thebaine content in the P. bracteatum originated from Polour region of Tehran.…”

Section: Resultsmentioning

confidence: 96%

Measurement of some Benzylisoquinoline Alkaloids in Different Organs of Persian Poppy during Ontogenetical Stages

Rezaei

Naghavi

Hosseinzadeh

et al. 2016

Chemistry & Biodiversity

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Papaver bracteatum, a perennial species, has been known as a rich source of thebaine and a potential alternative to Papaver somniferum for the production of codeine and some semisynthetic antagonist drugs. In this study, ion mobility spectrum (IMS) of the root, leaf, bottom part of stem, upper part of stem, capsule wall, petal, and capsule content during developmental stages of P. bracteatum including annual rosette, perennial rosette, bud initiation, pendulous bud, preflowering, and lancing were investigated. The IMS revealed thebaine, papaverine, and noscapine as the major components of the extracted alkaloids. Based on the results of the study it appears that, at least in part, there is a competition among the biosynthesis pathways of papaverine, noscapine, and morphinan alkaloids from a common source. Root and capsule wall were the most potent organs for extraction of thebaine, while lancing stage was the best developmental stage for thebaine exploitation. However, it seems that total biomass of root and capsule wall plays a key role in the final selection of favorite organ. Although papaverine and noscapine in the stem at preflowering stage had the most quantity, significant amounts were found in the capsule wall. In general, total alkaloid content of leaf was lower than the other plant parts.

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Thebaine Content of Selections of Papaver bracteatum Lindl. at Different Ages

Cited by 22 publications

References 4 publications

Papaver bracteatum – a Summary of Current Knowledge

Papaver bracteatum – a Summary of Current Knowledge

Papaver bracteatum Lindi.: Quantitative Extraction and Determination of Thebaine

Measurement of some Benzylisoquinoline Alkaloids in Different Organs of Persian Poppy during Ontogenetical Stages

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