The Volume of the Blood and Plasma in Health and Disease

Quantitative Aspects of Iron Deficiency in Hypochromic Anemia

“…The amount of iron given parenterally (within certain maximum limits) corresponds closely to the amount of iron gained in the circulating hemoglobin, and is apparently utilized to a very large extent in the building of new hemoglobin. 4. Because of the toxicity of iron administered parenterally in adequate dosage, and for practical and economic reasons, it is believed that it is undesirable to give iron parenterally rather than orally in most cases.…”

Intravenous Injections

“…Samples of blood were obtained from the femoral veins. The blood volume was determined at the beginning of most of the experiments by the dye method as outlined by Rowntree, Brown and Roth (3). The blood that was withdrawn was replaced in all instances by an equal quantity of blood obtained from another dog.…”

RED CELL, PLASMA AND BLOOD VOLUME IN HEALTHY MEN MEASURED BY RADIOCHROMIUM (Cr51) CELL TAGGING AND HEMATOCRIT: INFLUENCE OF AGE, SOMATOTYPE AND HABITS OF PHYSICAL ACTIVITY ON THE VARIANCE AFTER REGRESSION OF VOLUMES TO HEIGHT AND WEIGHT COMBINED*

“…However, in comparison with the work which has been done with the dye (1)(2)(3)(4)(5) and carbon monoxide (6) methods, little attention has been given to the establishment of mean values for men and women or to study of the variance encountered among healthy subjects. Most clinical investigators have collected their own control data, based often on study of relatively few or not entirely healthy subjects (7)(8)(9)(10)(11)(12)(13).…”