“…The zntA gene, which encodes the Zn(II)-export protein, also plays role in specific resistance to zinc, cadmium and lead in E. coli and is normally located in the bacterial chromosome (Rensing et al, 1997). The abundance of the zntA gene in E. coli isolates in this study may be associated with the widespread use of zinc in feed additives (Abd El-Hack et al, 2017;Keser et al, 2016;Lu, Lu, Chen, Zhang, & Fu, 2015). On the other hand, it has been reported that the rcnA gene provides resistance to both nickel and cobalt based on an efflux pump system in E. coli (Rodrigue, Effantin, & Mandrand-Berthelot, 2005).…”