The uncertain relationship between obesity and prostate cancer: An Italian biopsy cohort analysis

Metabolic abnormalities linked to an increased cardiovascular risk are associated with high-grade prostate cancer: a single biopsy cohort analysis

“…These data were similar to previous experiences from our centre and from other studies demonstrating a negative correlation between prostate volume and PCa diagnosis at biopsy. [12][13] Overall, PCa detection rate (40.4%) was the same as in other series in the extended biopsy protocol era. 14 Furthermore, our patients presented at least one metabolic abnormality among obesity, abnormal waist circumference and MS.…”

Relationship between BMI, PSA and Histopathological Tumor Grade in a Caucasian Population Affected by Prostate Cancer

“…However they detected a level of PSA higher among patients with high-grade tumor compared to subjects with low-grade [21], while in our study we found high levels of PSA in patients with low-grade tumors than in patients with Gleason score 6-7.…”

Effect of Obesity on Serum Prostate-Specific Antigen in Nigerian Men

“…Our study result has shown that overweight and obesity are highly prevalent among the cohort of men who volunteered for prostate cancer screening with 47.7% being either overweight or obese and with 64.6% having some degree of abdominal obesity. The possible risks of obesity in prostate cancer include: reduced detection rate because of lower serum PSA, high-grade disease (Gleason’s score ≥7) [29,30,31], increased biochemical recurrence after radical prostatectomy and increased mortality [26,32,33]. However, conversely, some studies did not confirm any inverse relationship of obesity with serum PSA [14,15,16,17].…”