The treatment of polycythemia vera

Reinhard, Edward H.; Hahneman, Betty M.

doi:10.1016/0021-9681(57)90028-0

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Survival Compared With Controls1

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1961

1972

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Cited by 16 publications

(1 citation statement)

References 27 publications

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“…dying with too little blood after suffering from too muchwould have attracted more attention if it had been seen as often as it has by us and by other observers (Masouredis and Lawrence, 1957;Reinhard and Hahneman, 1957;Tubiana et al, 1961 ;Modan and Lilienfeld, 1964;Osgood, 1964aOsgood, , 1964bPerkins et al, 1964;Halnan andRussell, 1965 Modan, 1965;Szur and Lewis, 1966). The only possibility of estimating the increased risk that radiophosphorus-treated patients have of dying of marrow failure is to refer again to Videbmk's series.…”

Section: Survival Compared With Controlsmentioning

confidence: 84%

Survival of polycythaemia vera patients treated with radioactive phosphorus.

Harman¹,

Ledlie²

1967

BMJ

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Section: Survival Compared With Controlsmentioning

confidence: 84%

Survival of polycythaemia vera patients treated with radioactive phosphorus.

Harman¹,

Ledlie²

1967

BMJ

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Muramidase in myeloproliferative disorders terminating in acute leukemia

Skarin

Matsuo

Moloney

1972

Cancer

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During serial studies of serum muramidase activity (SMA) over a 4‐year period on 168 patients with leukemia and myeloproliferative disorders (MPD) eight patients—one with polycythemia vera (PCV), one with agnogenic myeloid metaplasia, three with atypical myeloid metaplasia, and three with chronic myelogenous leukemia—developed acute myeloblastic or acute myelomonocytic leukemia (AMML). Onset of leukemia occurred early during the course of the disease and was associated with striking elevation of SMA in all six patients with AMML. Three patients studied in detail had significant hypokalemia possibly related to toxic effects of an excess of muramidase on renal tubules. Seven of the eight patients received therapy, consisting of splenic irradiation, alkylating agents, or both. Rapid rise of SMA in patients with MPD may herald the onset of acute leukemic metamorphosis.

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Polyglobulie und Polycythaemia vera

Stecher¹,

Reinhardt²

1970

Blut Und Blutkrankheiten

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The treatment of polycythemia vera

Cited by 16 publications

References 27 publications

Survival of polycythaemia vera patients treated with radioactive phosphorus.

Survival of polycythaemia vera patients treated with radioactive phosphorus.

Muramidase in myeloproliferative disorders terminating in acute leukemia

Polyglobulie und Polycythaemia vera

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