The treatment of incomplete miscarriage with oral misoprostol

Pandian, Zabeena; Ashok, Premila Wencesiaus; Templeton, Allan

doi:10.1016/s0306-5456(00)00024-3

Cited by 17 publications

(7 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, all patients had the diagnosis of miscarriage confirmed by ultrasonography which contrasts with other studies where some patients had their initial diagnosis confirmed clinically 6 . A reduced dose of mifepristone 5 , in combination with a single dose of misoprostol appears to give similar success rates to other treatment regimens 4,7 .…”

Section: Discussioncontrasting

confidence: 71%

Medical treatment of miscarriage in a district general hospital is safe and effective up to 12 weeks’ gestation

Greenland

Ogunbiyi

Bugg

et al. 2003

Current Medical Research and Opinion

View full text Add to dashboard Cite

The findings are reported of a retrospective study of 207 women undergoing medical evacuation of the uterus for first trimester miscarriage, using mifepristone followed by a single dose of oral misoprostol. All women had the diagnosis confirmed by ultrasonography. Complete medical evacuation was achieved in 88% of cases. The success rate and incidence of complications was observed to be the same regardless of whether gestation was below or above 9 weeks. The number of cases in which antibiotic treatment for presumed pelvic infection was prescribed was 3%. The incidence of anaemia requiring blood transfusion was 3%.

show abstract

Section: Discussioncontrasting

confidence: 71%

Medical treatment of miscarriage in a district general hospital is safe and effective up to 12 weeks’ gestation

Greenland

Ogunbiyi

Bugg

et al. 2003

Current Medical Research and Opinion

View full text Add to dashboard Cite

show abstract

“…Pandian et al [3] reported an 85% success with oral misoprostol in the United Kingdom, with a dose of misoprostol and a rate of incomplete miscarriages different from those used and observed in the present study, while a 83.3% success with vaginal misoprostol was observed in South Africa [4]. Misoprostol tablets are not prepared for vaginal use, and the ways they are prepared for vaginal administration may differ and cause differences in the drug's effect.…”

contrasting

confidence: 48%

Vaginal vs. oral misoprostol for mid‐trimester abortion

Nigam

Singh

Prakash

2006

Intl J Gynecology & Obste

View full text Add to dashboard Cite

“…5,9,10,12,14,19,20,[25][26][27][28][29][30][31][32][33][34][35][36][37][38]41 (Table 1) The success rate reported in trials is closely related to the length of time after treatment at which the uterus is reassessed by ultrasound exam. 16 Early studies on the use misoprostol for incomplete abortion tested a range of doses (400 mcg to 1200 mcg) and routes (oral, vaginal, intrauterine, etc.…”

Section: 2b Reports Of Efficacy From Studies Comparing Misoprostolmentioning

confidence: 99%

The medical management of missed miscarriage: outcomes from a prospective, single‐centre, Australian cohort

Petersen

Perkins

Gibbons

et al. 2013

Medical Journal of Australia

View full text Add to dashboard Cite

Objective: To report the prospective outcomes of medical management of missed miscarriage before 13 weeksˈ gestation from an Australian cohort. Design: Descriptive study of a cohort selected out of a randomised controlled trial. Setting: Outpatient management at a maternity hospital between 1 May 2007 and 28 July 2010. Participants: 264 women requesting medical management of missed miscarriage. Main outcome measures: Number of doses of misoprostol required, unscheduled visits for care, findings at ultrasound follow‐up, requirement for surgical management, number of cases of gestational trophoblastic disease (GTD), and self‐reported patient experience. Results: 107 women (40.5%) received a repeat dose of misoprostol, and 79 women (29.9%) made unscheduled visits for care. Among the 241 women with Day 7 ultrasound follow‐up, a gestational sac was found in 32 women (13.3%), indicating failure of medical management. Complete miscarriage was induced without the need for surgery in 206 women (78.0%). Surgery was performed as an emergency in 13 women (4.9%). Twelve women (4.5%) had surgery for ongoing bleeding after medical management, and four of these did not have chorionic villi on histopathological examination. Five women (1.9%) had GTD, which was managed incidentally under the protocol. Among those who returned patient questionnaires, 73.0% participants (116/159) indicated that they would recommend medical management of miscarriage to other women, while 18.2% (29/159) indicated that they would undergo surgery next time. Conclusion: The medical management of missed miscarriage on an outpatient basis is safe and effective. Trial registration: ACTRN12612000150842.

show abstract

The treatment of incomplete miscarriage with oral misoprostol

Cited by 17 publications

References 5 publications

Medical treatment of miscarriage in a district general hospital is safe and effective up to 12 weeks’ gestation

Medical treatment of miscarriage in a district general hospital is safe and effective up to 12 weeks’ gestation

Vaginal vs. oral misoprostol for mid‐trimester abortion

The medical management of missed miscarriage: outcomes from a prospective, single‐centre, Australian cohort

Contact Info

Product

Resources

About