The surgical treatment of hypertrophic intertriginous Darier's disease

Ahčan, Uroš; Dolenc‐Voljč, Mateja; Živec, Katarina; Zorman, Peter; Jurčić, Vesna

doi:10.1016/j.bjps.2008.06.060

Cited by 13 publications

(13 citation statements)

References 11 publications

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“…Photodynamic therapy with five aminolevulinic acid and surgical excision of hypertrophic intertriginous keratosis follicularis have also been reported. [ 24 ]…”

Section: Discussionmentioning

confidence: 99%

Darier disease: A rare genodermatosis

Suryawanshi

Dhobley

Sharma

et al. 2017

J Oral Maxillofac Pathol

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Darier disease (DD), also known as keratosis follicularis or dyskeratosis follicularis, is a rare autosomal dominant genodermatosis with high penetrance and variable expressivity. It is caused by mutations of ATP2A2 gene which encodes the sarco/endoplasmic reticulum Ca2+ ATPase isoform 2. It is clinically manifested by hyperkeratotic papules primarily affecting seborrheic areas on the head, neck and thorax, with less frequent involvement of the oral mucosa. When oral manifestations are present, they primarily affect the palatal and alveolar mucosa, are usually asymptomatic and are discovered in routine dental examination. Histologically, the lesions show suprabasal clefts with acantholytic and dyskeratotic cells. We present a case of 35-year-old female patient with typical clinical and histological features of DD.

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“…Photodynamic therapy with five aminolevulinic acid and surgical excision of hypertrophic intertriginous keratosis follicularis have also been reported. [ 24 ]…”

Section: Discussionmentioning

confidence: 99%

Darier disease: A rare genodermatosis

Suryawanshi

Dhobley

Sharma

et al. 2017

J Oral Maxillofac Pathol

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“…Latest reports also prove the efficiency of local therapy with diclofenac sodium 3% gel . Apart from the classic local and general treatment options available, scientific proofs of efficiency of photodynamic therapy , surgical treatment , electrotherapy, and laser therapy exist.…”

Section: Discussionmentioning

confidence: 99%

Darier-White disease treated with fractional CO₂laser in two cases

Raszewska-Famielec

Dudra-Jastrzębska

Borzęcki

et al. 2015

Dermatologic Therapy

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Darier-White disease is one of the most common genodermatoses. The most typical clinical symptoms such as diffuse hyperkeratotic papulae usually appear during puberty or early adulthood in seborrhoeic area. It is connected with substantial deterioration of the quality of life due to aesthetic defect. Although there exist many therapeutic options, the disease still causes considerable therapeutic difficulties. Treatment with fractional CO2 laser seems to be a promising therapeutic method. In this paper, we present two cases of patients with Darier's disease who have been treated with a fractional CO2 laser with very good clinical outcome.

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“…[3,9] Based on our experience and literature review, postoperative complications as infections or necrosis of the skin autograft are considerable risks in the surgical treatment of particular skin conditions, as unresponsive ulcers in erosive plantar lichen planus or severe Darier disease. [10] Hence, we proposed a combined treatment option, reinforcing the surgery with the positive effects of PRP and total nucleated cells (TNCs) in terms of decreased infection risks, exudate, haematomas, level of pain, increased velocity and chance of complete wound healing, better cutaneous trophism and final scar. [9,11] We present our preliminary observations with this innovative approach.…”

Section: Backg Rou N Dmentioning

confidence: 99%

“…Autologous PRP, as a rapid and safe accelerator of the healing process, has different clinical applications, in chronic and acute wound repair as well as in dental implant surgery and bone regeneration, aesthetic procedures, eye, cardiac and orthopaedic surgery, muscle and tendon repair also in sports injuries . Based on our experience and literature review, postoperative complications as infections or necrosis of the skin autograft are considerable risks in the surgical treatment of particular skin conditions, as unresponsive ulcers in erosive plantar lichen planus or severe Darier disease . Hence, we proposed a combined treatment option, reinforcing the surgery with the positive effects of PRP and total nucleated cells (TNCs) in terms of decreased infection risks, exudate, haematomas, level of pain, increased velocity and chance of complete wound healing, better cutaneous trophism and final scar .…”

Section: Introductionmentioning

confidence: 99%

Preliminary observations of a new approach to tissue repair: Peripheral blood mononuclear cells in platelet‐rich plasma injected into skin graft area

Orlandi¹,

Bondioli²,

Venturi³

et al. 2018

Experimental Dermatology

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Our purpose was accelerating the physiologic wound healing, stimulating tissue regeneration and the reparative tissue processes in resistant skin ulcers as in a case of an erosive lichen planus of the soles and after a surgical treatment as for severe Darier disease. The challenge was to establish an effective therapy to enhance tissue healing by the injection of a mixture of peripheral blood mononuclear cells (PB-MNCs) and platelet-rich plasma (PRP) into a skin autograft area. This new perioperative biotechnological approach enriches PRP with the effects of PB-MNCs. It offers a novel advanced strategy that could become an ideal biologic blood-derived therapy, whose components are entirely autologous and produced by a protocol independent by the operator.

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The surgical treatment of hypertrophic intertriginous Darier's disease

Cited by 13 publications

References 11 publications

Darier disease: A rare genodermatosis

Darier disease: A rare genodermatosis

Darier-White disease treated with fractional CO₂laser in two cases

Preliminary observations of a new approach to tissue repair: Peripheral blood mononuclear cells in platelet‐rich plasma injected into skin graft area

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The surgical treatment of hypertrophic intertriginous Darier's disease

Cited by 13 publications

References 11 publications

Darier disease: A rare genodermatosis

Darier disease: A rare genodermatosis

Darier-White disease treated with fractional CO2laser in two cases

Preliminary observations of a new approach to tissue repair: Peripheral blood mononuclear cells in platelet‐rich plasma injected into skin graft area

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Darier-White disease treated with fractional CO₂laser in two cases