The study of amino acid composition of sapropel by the capillary electrophoresis method

Strus, Oksana

doi:10.24959/nphj.15.2029

Cited by 3 publications

(5 citation statements)

References 6 publications

(6 reference statements)

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“…The objects of the research comprised the sapropel extract from Prybych deposits (Volyn region, Ukraine), obtained by the method of cavitation [7], and excipients that were used during development of composition of the emulsifying base: Corn oil, emulsifier no. 1 (a mixture of fatty alcohols of the fraction С 16 -С 20 of the sodium salt of sulfoether of fatty alcohols), Cetearyl alcohol, and purified water [15][16][17].…”

Section: Methodsmentioning

confidence: 99%

“…In these cases, the extraction of sapropel improves the environment due to the deepening of lake basins, and therefore, enhances the hydrological, hydrochemical, and biological regimen of lakes [5]. In sapropel, extracted from Prybych Lake, Volyn region, significant quantities of carboxylic acids [6], amino acids [7], micro-and macro-elements, and humic acids [8] were determined in our earlier investigations, that allows considering the natural raw material a perspective for the development of medicinal, cosmetic and veterinary products [5,9]. During the experimental studies, using cavitation method, we have improved the technology for preparation of the sapropel extract that provides a higher yield of humic and fulvic acids (above 20%) [8].…”

Section: Introductionmentioning

confidence: 99%

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The Investigation of the Development of a Cream Composition With the Sapropel Extract

Strus

Polovko

Plaskonis

2018

Asian J Pharm Clin Res

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Objective: The objective of this research was the development of cream with sapropel extract on the emulsifying base and the investigation of the possibility for cream samples to be in future applied in medicine, cosmetics, and veterinary.Methods: To carry out the research a set of methods (centrifugal, thermal, and potentiometric) to analyze colloidal and thermal stability and determine pH values of the tested samples were used. Organoleptic characteristics of the tested samples and possible signs of physical instability were studied. Rheological properties of the samples were determined on the rotating viscometer. The method of microscopic analysis was carried out to analyze the stability of the emulsion system.Results: The research outcomes revealed that all the prototype samples have thermal and colloid stability, neutral pH value, and consistency that depends on the content of the oil phase and the emulsifying mixture. The samples, containing 15% of Vaseline oil and 4% and 6% of emulsifier no. 1, have low viscosity indexes, and the sample with 10% of emulsifier has a rather dense consistency. The samples containing 20% of oil phase possess unsatisfactory organoleptic properties. Since the sample with 4% of emulsifier possessed low rates of viscosity and phase separation occurred during its storage.Microscopic studies have shown that the sample containing 6% of emulsifier no. 1 exhibits monodisperse and a uniform roundness of drops that indicates the stability of the system.Conclusion: The outcome of the research is the development of the composition of the cream with sapropel extract with the emulsifying base containing 15% of corn oil, 6% of emulsifier no. 1, and 1% of Cetostearyl alcohol and purified water.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Investigation of the Development of a Cream Composition With the Sapropel Extract

Strus

Polovko

Plaskonis

2018

Asian J Pharm Clin Res

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“…Sapropelic therapeutic muds exhibit the anti-inflammatory and anti-allergic effect, protect the skin from the damaging effects of free radicals, slow down the aging processes, providing for skin a freshness, firmness, and elasticity, also improve cellular regeneration, moisturize, and increase elasticity and thickness of the keratoid layer of the epidermis. [4,6] The uses of native products and individual components of sapropels for many years have shown their effectiveness, accessibility, convenience, and safety.…”

Section: Original Articlementioning

confidence: 99%

“…A mong promising raw materials for preparation of medical, veterinary and cosmetic remedies are sapropel, which is a unique natural organic material, containing a large number of carboxylic, humic and amino acids, vitamins, micro-and macro-elements, and possessing a wide range of pharmacological effects, as well anti-inflammatory, reparative, antibacterial, and antioxidant. [1][2][3][4] In scientific literature, the term "sapropel" has been used mostly in a generic sense for describing organic-rich fine-grained sediments deposited in stagnant water. In respect to physical and chemical properties, sapropels are diverse materials with different content of organic substances and mineral nutrient concentration.…”

Section: Introductionmentioning

confidence: 99%

Untitled

Strus¹

2019

IJGP

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Aim: The aim of the study was to work out the composition of cream with extract of sapropel from Prybych deposits, Volyn region, Ukraine, and to determine its organoleptic, physicochemical indices, structural and mechanical (rheological) parameters, colloidal and thermal stability, as well as to justify the choice of effective preservatives. Materials and Methods: The following materials were employed: Extract of sapropel from Prybych deposits; emulsion base, containing corn oil, emulsifier №1, cetylstearyl alcohol, and purified water. To carry out the research a set of methods (centrifugal, thermal, and potentiomentric), to analyze colloidal and thermal stability, and to determine pH values of the tested samples were used. Rheological properties of the samples were determined on the rotating viscometer. Results: There was determined the influence of the extract on physicochemical and rheological properties of the emulsion base; all the experimental samples remain thermally and colloidally stable and have satisfactory organoleptic properties; incorporation of SE into an emulsion base in a concentration of up to 20% retains structural and mechanical properties of the base. Conclusion: As the results of the carried out experimental investigations, the effect of the SE on physicochemical and rheological properties of its emulsion base. Microbiological research showed that the maximum reduction of the number of viable cells of microorganisms was observed applying as preservatives euxyl K 100 (0.1%) and nisin (0.01%).

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“…The experimental research has shown in the sapropel composition, extracted from Prybych Lake, the presence of significant amounts of carboxylic acids, amino acids, micro-and macroelements, humic acids (Nikolov 2014;Strus 2015a;Strus 2015b). The technology of sapropel extract production using the cavitation method was improved.…”

Section: Introductionmentioning

confidence: 99%

Justification of technological parameters of the cream production with sapropel extract

Strus¹,

Polovko²,

Yezerska³

2019

PHAR

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The aim of the research was to substantiate the technological parameters of cream production with the sapropel extract and work out the technological scheme for its production. In this study, extract of sapropel from the Prybych deposit, emulsion base, containing corn oil, emulsifier No.1, cetylstearyl alcohol, nisin, euxyl K 100 and purified water were employed. To carry out the research, a set of methods to analyse colloidal and thermal stability was used. Rheological properties of the samples were determined. The method of microscopic analysis was carried out to analyse the stability of the emulsion system. It was proved experimentally that, when producing the cream, it is appropriate to use the phase inversion method, and the emulsification needs to be carried out at 5000 r/m for 20 min. Size and shape of the sample drops, obtained at 5000 r/m, were monodisperse and more uniform, most of which range from 2 to 3 microns that indicates the system stability. The following parameters of technological process were determined: mixing temperature conditions, speed of homogenisation and mixing time.

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The study of amino acid composition of sapropel by the capillary electrophoresis method

Abstract: (histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine) and a number of nonessential ones (alanine, arginine, glycine, proline and serine). Alanine, glycine, leucine, and isoleucine prevail in the mixture analyzed.

Cited by 3 publications

References 6 publications

The Investigation of the Development of a Cream Composition With the Sapropel Extract

The Investigation of the Development of a Cream Composition With the Sapropel Extract

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Justification of technological parameters of the cream production with sapropel extract

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