The special extract ERr 731 of the roots of Rheum rhaponticum decreases anxiety and improves health state and general well-being in perimenopausal women

Abstract

ERr 731 is an effective medication for women with menopause-related anxiety and improves their health state and general well-being.

Herbal medicine for depression and anxiety:Asystematic review with assessment of potential psycho‐oncologic relevance

“…In menopausal women, extracts of blue green algae ( Aphanizomenon flos‐aquae ) (Genazzani et al, ), Cimicifuga foetida (Zheng et al, ), grape seed ( Vitis vinifera ; Terauchi et al, ), rhapontic rhubarb ( Rheum rhaponticum ; Kaszkin‐Bettag et al, ), rose tea (Tseng, Chen, & Yang, ), and wild yam ( Dioscorea alata ; Hsu, Kuo, Chang, Wu, & Huang, ) helped decrease symptom scores related to anxiety and depression. Whereas wild yam appears to work via estrogenic pathway, the blue green algae extract did not demonstrate any hormonal effects.…”

“…, grape seed (Vitis vinifera;Terauchi et al, 2014), rhapontic rhubarb (Rheum rhaponticum;Kaszkin-Bettag et al, 2007), rose tea(Tseng, Chen, & Yang, 2005), and wild yam (Dioscorea alata;…”

Long-term effects of the rhapontic rhubarb extract ERr 731® on estrogen-regulated targets in the uterus and on the bone in ovariectomized rats

“…In the present study we aimed to investigate the safety of a long-term dietary administration of ERr 731 ® as the extract has been administered as tablets in the clinical trials [9,[20][21][22]. Potential estrogenic effects on the uterine gene expression were tested after treatment of rats with two doses of ERr 731 ® over a 90-day period.…”

Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors

“…ERr reduces the occurrence and severity of climacteric symptoms during perimenopause in women and improves their health-related quality of life [9,10]. …”