The Role of the Total Cholesterol Level in the Assessment of the Severity of Myocardial Infarction

Sv, Rao; Gandhe, Mahendra Bhauraoji; Indira, Shrimati; Srilakshmi, P; Goswami, K.

doi:10.7860/jcdr/2013/5538.2994

Cited by 1 publication

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“…In the present study, TC was positively associated with coronary artery disease severity. This was consistent with earlier studies that reported an important role of TC in assessing the severity of myocardial infarction ( 22 ), and its significantly direct association with the higher probability ( 23 ) and mortality in CHD ( 24 , 25 ) and high CVD risk ( 26 ). A study by Bjorck et al ( 25 ) reported that, in Swedish patients between 1986 and 2002, more than half of the decrease in coronary heart disease mortality was mainly attributed to the reduction of cardiovascular risk factors, mainly a significant decrease in TC.…”

Section: Discussionsupporting

confidence: 93%

Identification of predictors for the comprehensive clinical risk and severity of coronary lesions of acute coronary syndrome

Sun

et al. 2023

Front. Cardiovasc. Med.

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BackgroundAcute coronary syndrome (ACS) is the most common cause of death in patients with coronary artery disease. The aim of the study was to identify the predictors of both comprehensive clinical risk and severity of coronary lesions by comprehensive use of GRACE and SYNTAX scores in patients with ACS.MethodsClinical data of 225 ACS patients who underwent coronary angiography between 2015 and 2016 were collected. Multiple logistic regression analysis (stepwise) was used to identify the predictors. The predictive ability of predictors and the model were determined using receiver operating characteristics analyses.ResultsMultivariable logistic regression analyses showed that high aspartate aminotransferase (AST) predicted the comprehensive clinical risk with odds ratios (ORs) and 95% confidence intervals (CIs) of 1.011 (1.002–1.021). High total cholesterol (TC) and red blood cell distribution width (RDW) predicted the severity of coronary lesions with ORs and 95% CIs of 1.517 (1.148–2.004) and 1.556 (1.195–2.028), respectively. Low prealbumin predicted both severity of coronary lesions and comprehensive clinical risk of ACS patients with ORs and 95% CIs of 0.743 (0.672–0.821) and 0.836 (0.769–0.909), respectively. The model with a combination of prealbumin and AST had the highest predictive efficacy for comprehensive clinical risk, and the combination of prealbumin, TC, and RDW had the highest predictive efficacy for the severity of coronary lesions. The sensitivity and specificity, and the optimal cut-off values of these four indexes were determined.ConclusionsFour predictors for the comprehensive clinical risk and severity of coronary lesions of ACS were identified, which provided important information for the early diagnosis and appropriate treatment of ACS.

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Section: Discussionsupporting

confidence: 93%

Identification of predictors for the comprehensive clinical risk and severity of coronary lesions of acute coronary syndrome

Sun

et al. 2023

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

show abstract

The Role of the Total Cholesterol Level in the Assessment of the Severity of Myocardial Infarction

Cited by 1 publication

References 6 publications

Identification of predictors for the comprehensive clinical risk and severity of coronary lesions of acute coronary syndrome

Identification of predictors for the comprehensive clinical risk and severity of coronary lesions of acute coronary syndrome

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