The role of Msx1 and Pax9 in pathogenetic mechanisms of tooth agenesis

Rahayu, Yani Corvianindya; Setyorini, Dyah

doi:10.20473/j.djmkg.v42.i3.p141-146

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2019

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“…Defects in MSX1 associate, especially with agenesis of second premolars and third molars, whereas the defects in PAX9 affect particularly the permanent molars. 12 A research conducted by Daw et al 9 in 2016 described a girl with oligodontia and her father with hypodontia. It was found that both affected individuals exhibit typical PAX9 mutation phenotypes.…”

Section: Discussionmentioning

confidence: 99%

Suspected Non-Syndromic Oligodontia – A Rare Case with 13 Agenesis

Sari¹,

Pradopo²,

Nelwan³

et al. 2019

Acta Med Philipp

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Oligodontia is a condition in which the patient has more than six ageneses, excluding the third molars. Whereas the absence of one tooth is quite common, oligodontia is a rare congenital condition that can happen with or without the syndrome. The condition happens due to disturbances during odontogenesis process. Management of oligodontia is a long-term process, and it involves prosthetic, restorative, and orthodontic treatment to support the oral function and esthetic of the patient. This article aims to report a rare case of agenesis of 13 permanent teeth (excluding third molars) in an 11-year-old girl and her treatment plan.

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Section: Discussionmentioning

confidence: 99%