The role of brain oscillations as functional correlates of cognitive systems: a study of frontal inhibitory control in alcoholism

Kamarajan, Chella; Porjesz, Bernice; Jones, Kevin; Choi, Keewhan; Chorlian, David B.; Padmanabhapillai, Ajayan; Rangaswamy, Madhavi; Stimus, Arthur T.; Begleiter, Henri

doi:10.1016/j.ijpsycho.2003.09.004

Cited by 146 publications

(173 citation statements)

References 236 publications

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“…In our previous study in alcoholics (Kamarajan et al 2004), we demonstrated that alcoholics had lower delta and theta activity in the NoGo condition, and reduced delta activity in the Go condition. In the present study, the OA subjects who are at high risk to develop alcoholism manifest these deficits in EROs and additionally manifest decreased theta activity in the Go condition, and markedly reduced activity in the theta and alpha1 bands in the NoGo condition.…”

Section: Discussionmentioning

confidence: 58%

“…Recently, we showed that alcoholics have deficient delta and theta oscillatory responses during the NoGo condition in a Go/NoGo task (Kamarajan et al 2004). Further, decreased NoGo-P3 amplitude has also been reported in alcoholics (Cohen et al 1997a;Kamarajan et al, 2005b) as well as in children of alcoholics (Cohen et al 1997b;Kamarajan et al, 2005a).…”

Section: Introductionmentioning

confidence: 83%

“…The experimental paradigm is identical to our previous studies and has been described elsewhere (Kamarajan et al 2004(Kamarajan et al , 2005a(Kamarajan et al , 2005b. There were three visual stimuli in the task: (i) a cross (fixation stimulus), (ii) a circle (Go or NoGo stimulus), and (iii) a dollar sign (reinforcement sign).…”

Section: Experimental Paradigmmentioning

confidence: 99%

“…This regional grouping may help in interpreting the findings in terms of the functional significance of different lobes of the cortex. Furthermore, many previous studies have used this lobe-wise grouping (e.g., Cohen et al, 1997a;Kamarajan et al, 2004;de Bruin et al, 2004).…”

Section: Statistical Analysesmentioning

confidence: 99%

“…Basar 1999, Basar et al 2001aSchurmann et al 2001), while theta rhythms are associated with different cognitive processes such as conscious awareness, episodic retrieval, recognition memory, and frontal inhibitory control (e.g. Klimesch et al 1994Klimesch et al , 2001aKlimesch et al , 2001bDoppelmayr et al 1998;Karakas et al 2000aKarakas et al , 2000bBasar et al 2001c;Kamarajan et al 2004). The slow alpha rhythm (8-10 Hz) has been reported to be modulated as a function of attentional demands (e.g.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Event-Related Oscillations in Offspring of Alcoholics: Neurocognitive Disinhibition as a Risk for Alcoholism

Kamarajan

Porjesz

Jones

et al. 2006

Biological Psychiatry

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108

101

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Section: Discussionmentioning

confidence: 58%

Section: Introductionmentioning

confidence: 83%

Section: Experimental Paradigmmentioning

confidence: 99%

Section: Statistical Analysesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Event-Related Oscillations in Offspring of Alcoholics: Neurocognitive Disinhibition as a Risk for Alcoholism

Kamarajan

Porjesz

Jones

et al. 2006

Biological Psychiatry

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108

101

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Prediction of dispositional dialectical thinking from resting‐state electroencephalography

et al. 2021

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This study aims to explore the possibility of predicting the dispositional level of dialectical thinking using resting-state electroencephalography signals. Thirty-four participants completed a self-reported measure of dialectical thinking, and their resting-state electroencephalography was recorded. After wave filtration and eye movement removal, time-frequency electroencephalography signals were converted into four frequency domains: delta (1-4 Hz), theta (4-7 Hz), alpha (7-13 Hz), and beta (13-30 Hz). Functional principal component analysis with B-spline approximation was then applied for feature reduction. Five machine learning methods (support vector regression, least absolute shrinkage and selection operator, K-nearest neighbors, random forest, and gradient boosting decision tree) were applied to the reduced features for prediction. The model ensemble technique was used to create the best performing final model. The results showed that the alpha wave of the electroencephalography signal in the early period (12-15 s) contributed most to the prediction of dialectical thinking. With data-driven electrode selection (FC1, FCz, Fz, FC3, Cz, AFz), the prediction model achieved an average coefficient of determination of 0.45 on 200 random test sets. Furthermore, a significant positive correlation was found between the alpha value of standardized low-resolution electromagnetic tomography activity in the right dorsal anterior cingulate cortex and dialectical self-scale score. The prefrontal and midline alpha oscillations of resting electroencephalography are good predictors of the dispositional level of dialectical thinking, possibly reflecting these brain structures' involvement in dialectical thinking.

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Topography, power, and current source density of theta oscillations during reward processing as markers for alcohol dependence

Kamarajan¹,

Rangaswamy²,

Manz³

et al. 2011

Human Brain Mapping

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Recent studies have linked alcoholism with a dysfunctional neural reward system. Although several electrophysiological studies have explored reward processing in healthy individuals, such studies in alcohol dependent individuals are quite rare. The present study examines theta oscillations during reward processing in abstinent alcoholics. The electroencephalogram (EEG) was recorded in 38 abstinent alcoholics and 38 healthy controls as they performed a single outcome gambling task which involved outcomes of either loss or gain of an amount (10¢ or 50¢) that was bet. Event-related theta band (3.0–7.0 Hz) power following each outcome stimulus was computed using the S-transform method. Theta power at the time window of the outcome-related negativity (ORN) and positivity (ORP) (200–500 ms) was compared across groups and outcome conditions. Additionally, behavioral data of impulsivity and task performance were analyzed. The alcoholic group showed significantly decreased theta power during reward processing compared to controls. Current Source Density (CSD) maps of alcoholics revealed weaker and diffuse source activity for all conditions and weaker bilateral prefrontal sources during the Loss 50 condition as compared to controls who manifested stronger and focused midline sources. Further, alcoholics exhibited increased impulsivity and risk-taking on the behavioral measures. A strong association between reduced anterior theta power and impulsive task-performance was observed. It is suggested that decreased power and weaker and diffuse CSD in alcoholics may be due to dysfunctional neural reward circuitry. The relationship among alcoholism, theta oscillations, reward processing and impulsivity could offer clues to understand brain circuitries that mediate reward processing and inhibitory control.

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The role of brain oscillations as functional correlates of cognitive systems: a study of frontal inhibitory control in alcoholism

Cited by 146 publications

References 236 publications

Event-Related Oscillations in Offspring of Alcoholics: Neurocognitive Disinhibition as a Risk for Alcoholism

Event-Related Oscillations in Offspring of Alcoholics: Neurocognitive Disinhibition as a Risk for Alcoholism

Prediction of dispositional dialectical thinking from resting‐state electroencephalography

Topography, power, and current source density of theta oscillations during reward processing as markers for alcohol dependence

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