The Relationship Between Smoking and Suicidal Behavior, Comorbidity, and Course of Illness in Bipolar Disorder

Ostacher, Michael J.; Nierenberg, Andrew A.; Perlis, Roy H.; Eidelman, Polina; Borrelli, David J.; Tran, Tanya; Ericson, Gianna Marzilli; Weiss, Roger D.; Sachs, Gary S.

doi:10.4088/jcp.v67n1210

Cited by 118 publications

(99 citation statements)

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“…This study adds to a growing body of literature suggesting that smoking may be an indicator of particularly negative outcomes among patients with bipolar and co-occurring substance use disorders (Oquendo et al, 2004;Ostacher et al, 2006;Waxmonsky et al, 2005), suggesting a need for further research on nicotine use in this population. Clinicians might take note of patients presenting with this constellation of characteristics and enhance efforts at treatment engagement and retention.…”

Section: Discussionmentioning

confidence: 90%

“…High rates of nicotine dependence have been welldocumented among both mentally ill and substance-dependent patients , although nicotine cessation is rarely a major focus of treatment for either mood or other substance use disorders (Currie et al, 2003;Richter et al, 2004). Recent research has identified a potentially deleterious relationship between smoking and mood disorders, with bipolar smokers having an increased number of suicide attempts (Oquendo et al, 2004;Ostacher et al, 2006), worse illness course (Ostacher et al, 2006), and higher illness severity, including more psychotic symptoms (Waxmonsky et al, 2005), and co-occurring anxiety, attention deficit hyperactivity, and substance use disorders (Ostacher et al, 2006;Waxmonsky et al, 2005). Our finding adds to the growing literature suggesting that cigarette smoking might be associated with a particularly negative course among patients with mood and substance use disorders.…”

Section: Discussionmentioning

confidence: 99%

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Predictors of dropout from group therapy among patients with bipolar and substance use disorders

Graff¹,

Griffin²,

Weiss³

2008

Drug and Alcohol Dependence

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Objective-Bipolar and substance use disorders frequently co-occur. Integrated treatment for these disorders has been shown to be effective at reducing substance use, but no study has examined attrition from dual diagnosis group therapy. The current study identified baseline demographic and clinical characteristics that predict treatment dropout among patients with co-occurring bipolar and substance use disorders.Method-Using binary and multivariate analyses, baseline data were analyzed as part of a randomized controlled trial of integrated group therapy for bipolar and substance use disorders.Results-Cigarette smoking, recent mood episode, and lack of a college education were strong predictors of dropout after controlling for demographic and substance use variables.Conclusions-Given the strength of smoking as a predictor of dropout as well as the high rate of smoking among this population, a greater focus on the relationship between smoking and bipolar disorder is warranted.

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Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Predictors of dropout from group therapy among patients with bipolar and substance use disorders

Graff¹,

Griffin²,

Weiss³

2008

Drug and Alcohol Dependence

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“…Smoking is assumed to be a measure of disease severity as well as caffeine consumption and alcohol and substance abuse (40). Psychosis (41,42) and suicide attempts (43,44) …”

Section: Resultsmentioning

confidence: 99%

Distinct clinical characteristics of familial and solitary patients with bipolar disorder

Atagün¹,

Cevahirli²,

Kara³

et al. 2011

JMOOD

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İki uçlu bozukluğu olan ailesel ve münferit hastaların farklı klinik özellikleri Amaç: İki uçlu bozukluk da dahil majör ruhsal bozukluklar ailelerde kümelenmektedirler. Ailesel olmayan, tek vakalar da görülmektedir ve ailesel ve ailesel olmayan vakalar klinik özellikler bakımından farklılık gösterebilirler. Aileselliği dikkate alan çalışmaların büyük bölümü aynı aileden hastalarda hastalığın benzer olan ve olmayan özelliklerini incelemişlerdir. Farklı ailelerden olan ve ailesel özelliklerine göre hastalık özelliklerinin karşılaştırıldığı yeterince çalışma yoktur. Bu çalışmada ailesel olan ve olmayan tip I iki uçlu bozukluğu olan hastaların klinik özellikler açısından incelenmesi ve karşılaştırılması amaçlanmıştır. Yöntem: Bu araştırma Bakırköy Prof. Dr. Mazhar Osman Ruh ve Sinir Hastalıkları Eğitim ve Araştırma Hastanesine bağlı Raşit Tahsin Duygudurum Merkezi'nde tedavi görmekte olan hastalarla yapıldı. İki uçlu bozukluğu olan 112 hastanın (69 kadın, 43 erkek, ortalama yaş: 41.54±11.19, dağılım aralığı: 22-75, ailesinde hastalık öyküsü olan 64, olmayan 48 hasta) tıbbi kayıtları incelendi ve veriler hastalardan ve birinci derece akrabalarından telefonla teyit edildi. Ailesinde hastalık öyküsü olmayan hastaların ailelerine sorularak ailelede başka hastanın olmadığı doğrulandı. Bulgular: Psikiyatrik ekhastalıklar, doğum sonrası depresyon oranları, nikotin bağımlılığı, karma hastalık dönemi geçirmiş hasta sayısı ve halen antipsikotik kullanan hasta sayısı aile öyküsü olan hasta grubunda istatistiksel olarak anlamlı derecede daha fazla oldukları saptanan özelliklerdi. Hastalık başlangıç yaşı, hastalık dönemi sayıları ve hastaneye yatış sayıları açısından gruplar arasında fark saptanmadı. Sonuç: Psikiyatrik ekhastalık, doğum sonrası depresyon, karma hastalık dönemleri ve sigara kullanma ailesinde hastlalık öyküsü olan hastalarda daha fazla oranda bulundukları tespit edilen klinik özelliklerdir ve iki uçluluk ile ilişkilidirler. Psikiyatrik ekhastalık ve postpartum dönem geçirmeye yatkınlık aile öyküsü olan hastalarda daha fazla görülmesi beklenebilir. Fakat klinik özelliklerin gruplarda farklılık gösterip göstermediğinin belirlenebilmesi için daha başka büyük örneklemli çalışmalar da gerekmektedir.

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“…This can be attributed to the association between a history of smoking in patients with a more severe course of illness and the increased risk of substance use disorder (30).…”

Section: Discussionmentioning

confidence: 99%

Factors Affecting the Risk of Mental Disorders in Patients With Bipolar Disorder in the West of Iran

Vosough¹,

Ghaleiha²,

Faradmal³

et al. 2016

Avicenna J Neuro Psych Physio

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Background: Drug addiction, obsessive compulsive disorders (OCD), and other anxiety disorders are the disorders most commonly found in patients with bipolar disorder. Objectives: The purpose of this study was to identify the factors affecting the risk of drug addiction, obsessive compulsive disorders, and other anxiety disorders in patients with bipolar disorder. Patients and Methods: In this retrospective cohort study, the medical records of 400 patients with bipolar disorder hospitalized in Hamadan, Iran, between 2008 and 2014 were examined. Patient information, including demographic characteristics and comorbidity, was collected. A data analysis was performed using a separate logistic regression for each disorder. The statistical package used was STATA software version 11. A P-value of less than 0.05 was considered statistically significant. Results: The mean (SD) age of the patients with bipolar disorder was 34.62 (1.68) years. Of the 400 patients with bipolar disorder, 135 (33.75%) patients had anxiety disorders, 67 (16.8%) patients suffered from drug addiction, and 45 (11%) patients had OCD. An association

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The Relationship Between Smoking and Suicidal Behavior, Comorbidity, and Course of Illness in Bipolar Disorder

Cited by 118 publications

References 0 publications

Predictors of dropout from group therapy among patients with bipolar and substance use disorders

Predictors of dropout from group therapy among patients with bipolar and substance use disorders

Distinct clinical characteristics of familial and solitary patients with bipolar disorder

Factors Affecting the Risk of Mental Disorders in Patients With Bipolar Disorder in the West of Iran

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