The Relationship between Hypomagnesaemia and Glycemic Control in Children with Type 1 Diabetes Mellitus

Asmaa, Moustafa N; Samira, Sayed Z

doi:10.4172/2155-6156.1000693

Cited by 4 publications

(6 citation statements)

References 15 publications

(18 reference statements)

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“…is result is similar with the study of many researchers. 6,9,15,16 Inconsistent with our result, some researchers did not observe any relationship between serum magnesium and glycemic status [17][18][19] . is di erence could be attributed to the di erence in study populations, degree of diabetic control among them and to the di erent methods of evaluating serum magnesium and HbA 1c .…”

Section: Discussionsupporting

confidence: 55%

“…A recent study in Egypt showed that there were 37.3% of the diabetic subjects had hypomagnesaemia. 9 Seyoum et al 13 found a higher percentage of hypomagnesaemia (65%) in their study. Contrary to our result, Zargar et al 14 , did not found any signi cant alteration in plasma magnesium level in type 1 diabetes mellitus.…”

Section: Discussionmentioning

confidence: 65%

“…7,8 Some researchers found in their studies that hypomagnesaemia occurred in 28.2% & 37.3% type 1 diabetic patient respectively with poor glycemic control. 6,9 Oral or intravenous supplementation of magnesium in T1DM patients results in increased levels of magnesium and optimization of glycemic control. 10,11 In the present study, we measured serum magnesium level in children and adolescents with T1DM and evaluated its relationship with glycemic control.…”

Section: Introductionmentioning

confidence: 99%

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Status of Serum Magnesium Level in Bangladeshi Children and Adolescents with Type 1 Diabetes Mellitus and its Relationship with Glycemic Control

et al. 2021

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Type 1 diabetes mellitus is one of the most common endocrine and metabolic disorder in children and adolescents. Alteration of serum magnesium level may be associated with metabolic control and diabetic complications. The aim of the study was to evaluate serum magnesium level and find out its relationship with glycemic control in type 1 diabetic children and adolescents. For this study 80 type 1 diabetic children & adolescents with age range 1 to 18 years and 80 aged matched healthy controls were enrolled from the outpatient department of Changing Diabetes in Children, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic disorders, General Hospital, Dhaka. Using a cross sectional design, we measured anthropometric parameters and serum magnesium level of all study subjects. We also estimate the fasting plasma glucose and HbA1c levels of the diabetic children and adolescents and controls. The mean ± SD of serum magnesium level was significantly lower in patient with type 1 DM compared to control (0.7 ± 0.1 vs 0.8 ± 0.1 mmol/L respectively; p= < 0.001). Lower level of magnesium was found in subjects with poor glycemic control compared to good glycemic control (0.6 ± 0.1 vs 0.8 ± 0.1 mmol/L respectively; p= < 0.001). This study showed that serum magnesium level was lowered in type 1 diabetic children and adolescents and it was strongly associated with poor glycemic control which potentially contributing to the early development of diabetic complications. Bangladesh Med J. 2019 Sep; 48 (3): 16-20

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Section: Discussionsupporting

confidence: 55%

Section: Discussionmentioning

confidence: 65%

Section: Introductionmentioning

confidence: 99%

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Status of Serum Magnesium Level in Bangladeshi Children and Adolescents with Type 1 Diabetes Mellitus and its Relationship with Glycemic Control

et al. 2021

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“…On the other hand study done in Egypt on 25 type I DM patients had shown significantly low serum magnesium levels in cases as compared to controls, also they have found negative correlation between duration of illness and serum magnesium levels. A study done in Egypt observed that the relation between serum magnesium levels and glycemic control, on 150 type I DM patients, it was observed that 37.3% of patients had hypomagnesemia and those patients had higher HbA1C levels as compared to rest [15].…”

Section: Discussionmentioning

confidence: 97%

Study of serum magnesium levels in type I diabetes mellitus patients: a case control study

Chaudhary

2019

Int J Pediatr Res

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Introduction and background: Magnesium is involved in insulin synthesis. Some studies claim that there is hypomagnesemia in type I diabetes patients and they have implicated its use to increase insulin production, reduce the complications. This study was done to know serum magnesium levels in type I diabetes patients and whether there is any significant correlation between serum magnesium levels and glycemic control. As there are variety of results found in different studies it was important to evaluate serum magnesium levels in type I DM patients and any scope of improvement of insulin levels by its supplementation. Materials and Methods: A case control study was done involving 44 cases, 44 sex and age matched controls. All patients less than 18yrs diagnosed with type I diabetes mellitus were included in study. Serum magnesium levels in cases and controls were compared. Percentage of hypomagnesemia in both groups, correlation between HbA1c levels and serum magnesium levels in cases were calculated. Results: 27.27% of type I DM whereas 11.4% of controls had hypomagnesemia. Mean serum magnesium level in cases and normal controls were 1.83 and 1.88 respectively (p 0.8). Conclusion: Hypomagnesemia in cases was more than double as compared to controls. Although, there was no significant difference between mean serum magnesium levels in cases and controls, no significant correlation between serum magnesium and HbA1C levels was found in cases. Therefore, magnesium supplementation in type I diabetes mellitus for improvement of insulin levels is not recommended.

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“…The results of the study show that serum magnesium levels were lowered in children and adolescents with T1DM. Also they have found low serum magnesium levels association with an increased risk of poor glycemic control, potentially contributing to the early development of diabetic complications [1].…”

Section: Introductionmentioning

confidence: 99%

Dietary Adherence in Type 1 and 2 Diabetes

W¹

2016

J Diabetes Metab

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The Relationship between Hypomagnesaemia and Glycemic Control in Children with Type 1 Diabetes Mellitus

Cited by 4 publications

References 15 publications

Status of Serum Magnesium Level in Bangladeshi Children and Adolescents with Type 1 Diabetes Mellitus and its Relationship with Glycemic Control

Status of Serum Magnesium Level in Bangladeshi Children and Adolescents with Type 1 Diabetes Mellitus and its Relationship with Glycemic Control

Study of serum magnesium levels in type I diabetes mellitus patients: a case control study

Dietary Adherence in Type 1 and 2 Diabetes

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