OBJECTIVES. Constraint-induced (CI) movement therapy has been shown recently to be promising for improving upper-limb function in children with cerebral palsy (CP). Because little is known about patient characteristics predicting treatment efficacy, not all children may benefit from this intervention. Here we examine the relationship between efficacy of a child-friendly form of CI therapy and age on involved upper-extremity function.DESIGN. Twenty children with hemiplegic CP age 4 to 13 years received CI therapy and completed evaluations. Based on established functional and neuromaturational changes in hand skill development, the children were divided into a "younger group" (age 4 -8 years, n ϭ 12) and "older group" (age 9 -13 years, n ϭ 8). Children wore a sling on their noninvolved upper extremity for 6 hours per day for 10 of 12 consecutive days, during which time they were engaged in play and functional activities. Each child was evaluated by trained evaluators who were blinded to the fact that the children received treatment. The evaluations took place once before the intervention and at 1 week, 1 month, and 6 months after the intervention. Efficacy was examined at the movement efficiency (Jebsen-Taylor Test of Hand Function, subtest 8 of the Bruininks-Oseretsky Test of Motor Proficiency), environmental (caregiver frequency and quality of involved upper-limb use), and impairment (strength, tactile sensitivity, and muscle tone) levels.RESULTS. Children in both age groups had significant improvements in involved hand-movement efficiency and environmental functional limitations, which were retained through the 6-month posttest. However, there were no differences in efficacy between younger and older children. Both hand severity and the children's behavior during testing (number of redirections), with the latter serving as a reasonable correlate for attention during the intervention, were related to changes in performance in the younger group but not in the older group.
IMPAIRED HAND FUNCTION is a major disability in children with hemiplegic cerebral palsy (CP). As a result, children with hemiplegic CP often fail to use the involved upper extremity and learn to perform most tasks exclusively with their noninvolved upper extremity (ie, developmental disuse). 1 This disuse, in turn, may lead to additional impairments secondary to neural damage associated with CP. Interestingly, we have found that, in the laboratory environment, repetitive practice of a motor task with the involved hand can result in improved performance 2,3 in a relatively short time period. This observation suggests that the involved upper extremity is amenable to treatment and that intensive practice may be beneficial to improve function.A recent therapeutic intervention, constraint-induced (CI) movement therapy, seems promising for children with hemiplegic CP. It provides an opportunity for such practice with the involved hand and arm as a result of restraining the noninvolved upper extremity along with providing structured practice (...