The Relation of Blood Platelets to Hemorrhagic Disease

Abstract

mine a regional symptom of a septicemia or abscess of the gravest character. The micro-organisms, if they act on the spot, first seek the alveolus (alveolodental periostitis) then the inaudible ( osteoperiosl il is. osteo¬ myelitis of the jaws), or conjointly hone and mucous 'inillg. If they follow the eontigUOUS tissues of the mouth, we gel stenoparntiditis ; if they penetrate through the alveolus of an upper tooth (lirsl or second molar); maxillary sinusitis. If they pass on to the airpassages, bPOBchopneuHionia follows. If they enter into lll(' digestive apparatus they produce or help to produce 111 people subject to chronic abscessed teeth, anemia or so-called "denial cachexia" of Lejars," or the ¡ici.I Putrid intoxication of Wichet."' Everyone who has fol¬ lowed ibe clinical evolution of the lymphoph-Iégmonous s,'Ptieeniia of ihe neck knows that it may he either S1|ii|>le septicemia or septk pyemia. If an incision is mflde in the phlegmonous parts, it is with great troublé that one will find in ihe deep parts a minute suppuiat-'"g point containing only a dram or so of a secretion whieh may not be pus in character; or nothing at all '"•i.v be found. Here is a clear proof thai we must dis¬ mast BUrgica] iule, lions which do not: suppu rale. Sup-P'iraiion may be a means of defense for the organism. .'" many of these severe eases death conies on very rap-"".vthe nerve centers being profoundly affected and not giving the brain lime In react under the cellular intoxi¬ cation, while the patient has a slight delirium, but depression irregularity and weakness of ihe pulse, respi¬ ratory insufficiency, dyspnea, toxins thrown ofï by sweats, diarrhea and albuminuria.1,1 ' ! Morse Avenue.ABSTRACT OK DISCUSSION l,u-M. if. Vi.KTciiKii. Cincinnati: The thing that presents "-' 'f most forcibly to me is the luck of knowledge in parents 01 the laws of physiology. That is, the lack of proper knowl¬ edge of the eon,liiions under which to bring up children, ¡mil ''"ni our view point ihe moni Ii is very important: I have ''' ul in various works 11,al the saliva ol' animals is strongly alkaline, but to o,, to the abattoir, apply a bit of litmus paper to the saliva of animals an.I find it change as quickly l'"11' acid to alkaline ¡is it would be in a solution of biearb-«iinile ol' soda, and liud this in absolutely every case, is soinc-"'"¡K that should be considered by us. 1 take it that civilized environment has changed the physiology of man to almosi ""' opposite condition. For it is a rare thing to find human Kl'llv'' more i han barely alkaline. Now, with the strong a'kalin(.edition found in the mouths of animals, no acid flecfty could exist. Again; the eating of tbe rough food by '''"'"" animals constantly rubbing against their emnis. keeps t;i' tissues healthy and strong. This Feature is of great im POrtánce for there is a development of large rolls of con-'"'.'live tissue ,,,-callus at the necks of the teeth of these "minais, especially just insid.' the lower front teeth, where V"' food cines in contact with the mucous membran...

Platelet function testing: practice among UK National External Quality Assessment Scheme for Blood Coagulation participants, 2006

“…However, little progress has been made in the standardisation and performance of these tests, despite comments reported by the haemostasis task force of the British Committee for Standards in Haematology in 1988 6. The bleeding time has been in use for almost 100 years since its description by Duke8 and remains the only practical evaluation of ex vivo haemostatic response. However, standardisation of this relatively straightforward test seems hard to achieve.…”

Role of red blood cells in haemostasis and thrombosis

“…More than a hundred years ago it was reported that in anemia patients the bleeding time was prolonged irrespective of the platelet count [1]. Fifty years later a more general correlation between low hematocrit and prolonged bleeding times was found, including correction of the hemostatic parameters by blood transfusion [2].…”

Combined Antihaemophilic Globulin and Christmas Factor Deficiency in Haemophilia

“…Methods Platelets were counted by the method of Van Goidsenhoven (1926). The clotting-time was determined by the Lee and White (1913) by Duke's (1910) technique, the one-stage prothrombin time as described by Biggs and Macfarlane (1953), and the heparin-tolerance test and prothrombin consumption test by minor modifications of Soulier's techniques (Soulier, 1948;Soulier and Le Bolloch, 1950;Verstraete et al, 1954). The thromboplastin generation test has been performed according to the technique of Biggs and Douglas (1953).…”