The recovery cycle of the averaged auditory evoked response during sleep in normal children

Effects of Behavioural State on Visual Processing in Neonates

“…In accord with these neurophysiological findings from animal studies, non-invasive auditory and somatosensory evoked potential recordings during sleep and wakefulness across the human life span show marked effects of state on the response waveform, latency and amplitude of the corresponding neuronal substrates (9, 14, 25,29,32,42,45,55,61,63,64).…”

A Comparison of the mismatch negativity and a differential waveform response

“…Researchers have reported a significantly greater attenuation of the MMN response for stimuli delivered at longer ISIs in specific clinical populations including the elderly (Gaeta et al 1992;Woods 1992;Pekkonen et al 1996), children with CATCH-22 syndrome learning problems (Kraus et al 1996;Cheour et al 1997), and those suffering from Parkinson's disease (Pekkonen et al 1994), Alzheimer's disease (Kazmerski et al 1997), chronic alcoholism (Ahveninen et al 2000;Grau et al 2001), and coma (Kane et al 1993). Since certain neural refractory functions are also known to vary with different forms of CNS dysfunction (Shagrass et al 1971;Alho et al 1994;Ornitz et al 1974;Papanicolaou et al 1984;Shucard et al 1984), it is possible that in some studies, the MMN response and neural refractory effects may temporally overlap. If that were the case, erroneous interpretations of the clinical significance of the altered waveform morphology could result.…”