Abstract:The reaction of 2-ethoxy-1,3-dithiolane with carbonyl compounds such as aldehydes and ketones was investigated. The reaction proceeded smoothly in the presence of the HgCl2-catalyst to afford 2-substituted and 2,2-disubstituted 1,3-dithiolanes. The reaction also offers an interesting alternative to the previously reported methods of synthesizing 1,3-dithiolanes which involve the acid-catalyzed reaction of carbonyl compounds with 1,2-ethanedithiol.
“…An alternative method for the synthesis of 1,3-dithiolanes 205 from acid-sensitive carbonyl compounds involves the reaction of 2-ethoxy-1,3-dithiolane (204) in the presence of mercury(II) chloride or other Lewis acids (Scheme 11.61) [179]. …”
Section: Ring Transformations Of Heterocycles Leading To 13-dithiolamentioning
“…An alternative method for the synthesis of 1,3-dithiolanes 205 from acid-sensitive carbonyl compounds involves the reaction of 2-ethoxy-1,3-dithiolane (204) in the presence of mercury(II) chloride or other Lewis acids (Scheme 11.61) [179]. …”
Section: Ring Transformations Of Heterocycles Leading To 13-dithiolamentioning
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