The rapid and progressive degeneration of the cervical multifidus in whiplash: A MRI study of fatty infiltration

Elliott, James M.; Courtney, D. Mark; Rademaker, Alfred; Pinto, Daniel; Sterling, Mona; Parrish, Todd B.

doi:10.1016/j.math.2016.10.051

Cited by 19 publications

(49 citation statements)

References 33 publications

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“…This suggests that the presence of symptoms may not be relevant, although this does not comply with other published data which reports that muscle fat infiltrate is associated with the NDI score [48,49]. However, it is important to note that…”

Section: Accepted Manuscriptcontrasting

confidence: 60%

Evidence for cervical muscle morphometric changes on magnetic resonance images after whiplash: A systematic review and meta-analysis

Owers

Perriman

Smith

et al. 2018

Injury

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Section: Accepted Manuscriptcontrasting

confidence: 60%

Evidence for cervical muscle morphometric changes on magnetic resonance images after whiplash: A systematic review and meta-analysis

Owers

Perriman

Smith

et al. 2018

Injury

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“…There are studies which show fatty degeneration of multifidus to occur in lower back pain and sciatica patients. The mechanism is poorly understood, although disuse and inflammatory etiology are hypothesized, but this does not imply infection.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the location of the paraspinal tissue sample was purposely taken from tissue that is exposed as part of the surgical corridor for the surgical intervention but not immediately adjacent to the disc. There are studies which show fatty degeneration of multifidus to occur in lower back pain and sciatica patients 19,20 . The mechanism is poorly understood, although disuse and inflammatory etiology are hypothesized, but this does not imply infection.…”

Section: Can Paraspinal Tissue Be a Suitable Contaminant Control Or Cmentioning

confidence: 99%

Degenerate‐disc Infection Study with Contaminant Control: Discussion on the Research Methods

Rao

Chau

Phan

et al. 2018

Orthopaedic Surgery

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“…A strategy to address this limitation could be the use of quantitative assessment of adipose content of LAA meniscoids to guide evaluation of meniscoid composition, such as through the use of fat/water separation imaging sequences [10], allowing calculation of fat fraction of tissue within a region of interest (ROI). Quantitative calculation of fat content of musculoskeletal tissue has been undertaken in a number of contexts including the cervical spine [11] and leg [12]. However to date, no study has validated the use of fat/water separation imaging sequences to assess the composition of LAA joint meniscoids.…”

Section: Introductionmentioning

confidence: 99%

Quantitative magnetic resonance imaging assessment of lateral atlantoaxial joint meniscoid composition: a validation study

et al. 2019

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2 AbstractPurpose: Lateral atlantoaxial (LAA) joint meniscoid composition may have clinical significance in patients following neck trauma. However, the existing method of radiologically assessing meniscoid composition has an inherent element of subjectivity, which could contribute to measurement variability. The present study sought to investigate the accuracy of 2 point Dixon fat/water separation MRI as a quantitative assessment of LAA joint meniscoid composition. Methods: Sixteen LAA joint meniscoids were excised from four cadavers (mean [SD] age 79.5 [3.7] years; one female) following cervical spine MRI (2-point Dixon, T1-weighted VIBE and T2-weighted SPACE sequences). Composition of LAA joint meniscoids was undertaken by i) histological examination by light microscopy, ii) calculation of fat fraction by Dixon MRI (both In-phase/Opposedphase and Fat/Water methods), and iii) the existing method of considering VIBE and SPACE signal intensities. Analysis was performed using the kappa statistic with linear weighting. Results: Microscopy revealed three, five and eight meniscoids to be composed of adipose, fibroadipose and fibrous tissues, respectively. Dixon sequence MRI classified 11 of these meniscoids correctly, with 'substantial' level of agreement (In-phase/Opp-phase kappa statistic = 0.78 [95% CI 0.38, 1.17]; Fat/Water kappa statistic = 0.72 [95% CI 0.32, 1.11]). Level of agreement between microscopy and the VIBE and SPACE method was 'poor' (kappa statistic = 0.02 [95% CI -0.34, 0.38]).Conclusions: Findings suggest that Dixon fat/water separation MRI may have superior utility in the assessment of LAA joint meniscoid composition than the existing method of considering VIBE and SPACE signal intensities.

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The rapid and progressive degeneration of the cervical multifidus in whiplash: A MRI study of fatty infiltration

Cited by 19 publications

References 33 publications

Evidence for cervical muscle morphometric changes on magnetic resonance images after whiplash: A systematic review and meta-analysis

Evidence for cervical muscle morphometric changes on magnetic resonance images after whiplash: A systematic review and meta-analysis

Degenerate‐disc Infection Study with Contaminant Control: Discussion on the Research Methods

Quantitative magnetic resonance imaging assessment of lateral atlantoaxial joint meniscoid composition: a validation study

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