The Quality of Rat Brain Spatial Memory and Expression of Peroxisome Proliferator Activated Receptor (PPAR) Which Fed with Seluang (Rasbora spp.)

The seluang fish (Rasbora spp.) diet to improve neurotoxicity of endosulfan-induced intrauterine pup's brain through of oxidative mechanism

“…The MDA level decreased, and the enzymatic antioxidant activity was improved. Cysteine levels which act as antioxidants in Seluang fish are 0.32 mg/100 g. Seluang fish also contain glycine and glutamate [12]. In in vitro, cysteine plays a role in the binding of various types of free radicals, one of which is OH, whereas in vivo, cysteine together with glycine and glutamate are precursors of glutathione enzymes; enzymes that play a role in reducing oxidation of ROS [24].…”

“…Seluang fish also contains DHA with levels of 1.04 g/100 gr [12]. Docosahexaenoic acid (DHA) is one of the unsaturated fatty acids and is an essential fatty acid, which cannot be made by the body so it should be obtained from the outside.…”

“…The previous study from Triawanti et al reported that seluang fish could improve nutritional status in rats after malnutrition [11]. A study by Yunanto et al proved that white rats fed with seluang fish had better spatial memory and higher PPARg and PPARa expressions compared to rats fed by standard feed [12]. Triawanti et al study had proven that seluang fish can improve the oxidative stress condition of the brain after malnutrition [13].…”

Uji Aktivitas Ekstrak Etanol 96% Buah Stroberi Terhadap Peningkatan Memori Spasial Pada Tikus Model Demensia

“…T-maze dapat digunakan dalam berbagai cara untuk menilai kemampuan kognitif hewan. Lengan samping (tujuan) dapat berisi rangsangan (isyarat) seperti pola atau objek yang harus ditanggapi oleh hewan, umumnya untuk mendapatkan hadiah (Yunanto, Dwi Sanyoto, Syahadatina Noor, Kustiyah Oktaviyanti, & Triawanti, 2016).…”

Pengaruh Aktivitas Fisik Terhadap Peningkatan Kemampuan Memori Jangka Panjang

“…Sebagai hasil dari aktivitas otak sebelumnya, memori secara fisiologis disebabkan oleh perubahan kapasitas propagasi sinaptik dari satu neuron ke neuron berikutnya (Sinarsari, 2021;Yunanto et al, 2016). Memori jangka panjang dan memori jangka pendek membentuk memori atau sistem memori.…”