The Prospect of Incidental Detection of Unsuspected Skeletal Tuberculosis by Bone Scintigraphy Should Not Be Overlooked

Abstract

Our results indicate that pulmonary or systemic tuberculosis is not a prerequisite for skeletal tuberculosis. Skeletal tuberculosis should be among the differential diagnoses when there is a positive bone scan in patients without a malignancy in an endemic region.

Lung Sequestration and Pott Disease Masquerading as Primary Lung Cancer With Bone Metastases on FDG PET/CT

“…7,8 However, in our case, no tuberculosis of the lungs or any other organs except for the spine was identified, which was consistent with the notion that in many Asian countries skeletal tuberculosis did not always have concurrent extraskeletal tuberculosis. 9 Secondly, it has been well published that 2 coexisting different types of malignancies can both have significant FDG uptake on PET scans and will frequently be interpreted as a single type of malignancy with metastases. 10 -13 In comparison, we reported that 2 coexisting distinct nonmalignant processes masqueraded as primary malignancy with metastases on PET or PET/CT.…”

Multifocal osteoarticular tuberculosis of the extremities in an immunocompetent young man without pulmonary disease: A case report

“…MRI can be used to discriminate between abscesses and granulation tissue, delineate soft-tissue mass and identify the amount of bone destruction (16); however, MRI may not be appropriate for whole-body imaging as it is expensive and time-consuming (17). Bone scans, on the other hand, play an important role in the diagnosis and evaluation of TB (17,18), since they can detect unsuspected osseous TB in patients without known systemic diseases, particularly patients suffering from pain but without known malignancies. Bone scans also help to determine the optimal biopsy site and the most suitable area for insightful MRI imaging.…”

“…Bone scans also help to determine the optimal biopsy site and the most suitable area for insightful MRI imaging. Bone TB should be considered among the differential diagnoses when positive bone scans are observed in patients with unknown causes of bone pain, particularly in patients who do not have a known history of malignancy (17,19).…”

Primary Osteosarcoma of the Rib Identified on Bone Scintigraphy

“…[5][6][7][8] Most positive findings on bone scan in relatively young patients with back pain are due to non-malignant etiology, such spondylolysis, osteomyelitis, or osteoid osteoma. [9][10][11][12][13][14][15] However, different malignant disorders, 16,17 including the current one, can also be incidentally identified in young patients with back pain.…”