The prevalence, awareness, treatment and control of dyslipidemia among adults in China

Pan, Ling; Yang, Zhenhua; Wu, Yue; Yin, Rong; Liao, Yunhua; Wang, Jinwei; Gao, Bixia; Zhang, Luxia

doi:10.1016/j.atherosclerosis.2016.02.006

Cited by 308 publications

(314 citation statements)

References 19 publications

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“…In addition, people with underlying chronic diseases, such as hypertension, or diabetes mellitus were at a higher risk of dyslipidemia. These results were partly consistent with many previous studies [18, 20, 21, 23]. It may reflect that factors associated with dyslipidemia and the consequences of dyslipidemia (such as overweight or obesity) are similar among different ethnicities.…”

Section: Discussionsupporting

confidence: 92%

“…Our study also showed that high triglyceride was the most prevalent form of dyslipidemia in northeast Chinese adults aged 40 years and over, followed by high total cholesterol (the prevalence of high total cholesterol, triglyceride, low-density lipoprotein cholesterol, and low high-density lipoprotein cholesterol were 33.5, 43.9, 0.6, and 8.8%, respectively). This was consistent with the overall pooled analysis, including thirty-eight studies on the epidemiology of dyslipidemia in Chinese adults [13]; however, this was different from many other national cross-sectional studies [18, 20, 21], in which low high-density lipoprotein cholesterol or high low-density lipoprotein cholesterol was the major type of dyslipidemia. In addition to the differences in methodology and population demography, local climate conditions, dietary habits, and sedentary lifestyles might contribute to the high prevalence of dyslipidemia [22], especially high triglyceride and high total cholesterol in the northeast Chinese adults aged 40 years and over.…”

Section: Discussionsupporting

confidence: 86%

“…In this representative sample of northeast Chinese adults aged 40 years and over of our study, the overall prevalence of dyslipidemia was 62.1%, with 58.6%, 64.4%, 65.7%, 63.3% in the age groups of 40–49, 50–59, 60–69, and over 70 years old, respectively. These prevalence rates in each age group over 40 years were significantly higher than data reported by the China National Survey of Chronic Kidney Disease Working Group, conducted from January 2007 to October 2010 [18, 19]. The cross-sectional survey covered 13 provinces but did not contain any provinces in northeast China, reporting that the adjusted prevalence of dyslipidemia in Chinese adults in the age groups of 40–49, 50–59, 60–69, and over 70 years old was 43.6, 46.8, 45.3, and 42.9%, respectively, for males, and 23.5, 39.9, 50.0, and 46.6%, respectively, for females.…”

Section: Discussionmentioning

confidence: 57%

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The prevalence, awareness, treatment, and control of dyslipidemia in northeast China: a population-based cross-sectional survey

Zhang

Xing

et al. 2017

Lipids Health Dis

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BackgroundDyslipidemia is an important independent modifiable risk factor for cardiovascular disease. The aim of this study was to explore the current prevalence, awareness, treatment and control of dyslipidemia and its associated influence factors in northeast China.MethodsIn this population-based cross-sectional study, we adopted a multi-stage, stratified sampling method to obtain a representative sample of 4052 permanent residents aged 40 years and over from different urban and rural regions in Dehui City of Jilin Province. All subjects completed a questionnaire and were examined for risk factors. Continuous data were presented as means ± standard deviations (SD) and compared using the Student’s t-test. Categorical variables were presented as proportions and compared using the Rao-Scott-χ 2 test in different subgroups. The associated influence factors for the prevalence, awareness, treatment and control of dyslipidemia were evaluated through multivariate logistic regression.ResultsThe prevalence of dyslipidemia was 62.1% overall, with 33.5, 43.9, 0.6, and 8.8% for high total cholesterol, triglyceride, low-density lipoprotein cholesterol, and low high-density lipoprotein cholesterol, respectively. Among those with dyslipidemia, the proportion of subjects who were aware, treated, and controlled was 14.4, 33.9, and 19.9%, respectively. Overweight or obesity (OR = 2.156; 95% CI: 1.863, 2.533), hypertension (OR = 1.643; 95% CI: 1.425, 1.893), or diabetes mellitus (OR = 2.173; 95% CI: 1.661, 2.844) increased the prevalence of dyslipidemia, also these participants were more likely to be aware of their condition, however, this did not increase the likelihood of treatment and control. Living in urban areas and higher education level also increased the awareness of dyslipidemia. Personal history of coronary heart disease was the strongest influence factors associated with better awareness, treatment and control of dyslipidemia. Overweight or obesity (OR = 0.404; 95% CI: 0.235, 0.695) and lack of exercise (OR = 0.423; 95% CI: 0.215, 0.830) were associated with poor control of dyslipidemia.ConclusionThe prevalence of dyslipidemia among adults aged 40 years and over in northeast China was high, however, the awareness, treatment, and control of dyslipidemia was measured at far from desirable levels. Renewed efforts taking influence factors into account are needed to improve the current unsatisfactory condition.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 57%

See 1 more Smart Citation

The prevalence, awareness, treatment, and control of dyslipidemia in northeast China: a population-based cross-sectional survey

Zhang

Xing

et al. 2017

Lipids Health Dis

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“…The types of dyslipidemia in Asian countries including China are mainly manifested as hypertriglyceridemia and low HDL-C, which is different from those in the United States and Europe [2, 5, 17]. In this study, the occurrence of dyslipidemia was 57.3 %, with the incidence of hypertriglyceridemia and low HDL-C at 44.4 % and 30.8 %, respectively, which is slightly higher than the recent epidemiological findings [5], but basically reflects the abnormal status of blood lipids in this region. PET/CT scan showed that the occurrence of aBAT in 717 subjects was 1.8 %, which was similar to that in other neighboring cities with similar latitude.…”

Section: Discussionmentioning

confidence: 99%

“…Due to the low dietary intake of fat and cholesterol, the type of dyslipidemia (mainly hypertriglyceridemia and low high-density lipoprotein cholesterol) in Chinese adult is different from those in Western countries. More importantly, evidence suggests that the prevalence of dyslipidemia in China is significantly increased over the past several years [2, 5]. …”

Section: Introductionmentioning

confidence: 99%

The role of active brown adipose tissue (aBAT) in lipid metabolism in healthy Chinese adults

et al. 2016

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BackgroundThe prevalence of dyslipidemia in China was increased over the last several years. Studies have shown that the activity of aBAT is related to the lipid metabolism. In this study, we analyzed blood lipid level in tumor-free healthy Chinese adults in order to determine the role of aBAT in lipid metabolism.MethodsWe retrospectively analyzed the factors that affect the blood lipid level in 717 tumor-free healthy adults who received blood lipid measurement and PET/CT scan by multivariate regression analysis. We also determined the role of aBAT on lipid profile by case–control study.Results(1) Our results showed that 411 (57.3 %) subjects had dyslipidemia. The prevalence of the subjects with hypercholesteremia, hypertriglyceridemia, low high-density lipoprotein cholesterol and high low-density lipoprotein cholesterol was 9.5 %, 44.4 %, 30.8 % and 1.4 %, respectively. Multivariate logistic regression analysis with dyslipidemia as the dependent variable showed that body mass index (BMI) and smoking are independent risk factors for dyslipidemia (OR > 1, P < 0.05), while the presence of aBAT is the independent protective factor for dyslipidemia (OR < 1, P < 0.05). (2) The incidence of aBAT was 1.81 %. Subjects with aBAT had significantly lower serum triglyceride and higher serum high-density lipoprotein cholesterol than the subjects without aBAT. The serum total cholesterol and low-density lipoprotein cholesterol were not significantly different between the subjects with aBAT and those without aBAT.ConclusionsDyslipidemia is caused by multiple factors and the presence of aBAT is a protective factor for dyslipidemia in healthy Chinese adults.

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Analysis of epidemiological trends in chronic diseases of Chinese residents

Wang

Cui

et al. 2020

Aging Medicine

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Beijing, and proposed making health a strategic priority to accelerate public health and fitness in China. 1,2 In October 2016, the Central Committee of the Communist Party of China and the State Council promulgated the Outline of Healthy China 2030 Plan, which specified that the core concept in prioritizing health is a more accurate positioning for the development of health and fitness in the long run as it focuses on the all-round development and health of a greater number of people. 1 People's health management has become an important national strategy because of the great importance attached to health by China's policy-makers. 3 Due to social and economic development, progress in medical and health services, and changes in people's lifestyles, the spectrum of disease among Chinese people has profoundly changed. A growing number of Chinese residents are contracting chronic diseases that are closely associated with environmental factors and unhealthy lifestyles. Five chronic diseases-cardiovascular diseases, tumors, diabetes, respiratory diseases, and mental disorders-have been identified as having a far-reaching impact on the country's medical and economic systems over the next two decades, according to a renewed warning by the Global Risks Report 2011. 2 The deaths caused by chronic diseases in China account for 87% of total deaths. The burden of chronic diseases has accounted for approximately 70% of the total burden of diseases in China, thus posing a tough challenge for the prevention and treatment of chronic diseases. 4 Additionally, nearly 300 million Chinese people suffer from hypertension and being overweight. It has been estimated that approximately 100 million Chinese people contract diabetes and chronic obstructive pulmonary disease (COPD) and more than 10 million people suffer from stroke, coronary heart disease (CHD), and obesity, respectively. These diseases not only consume considerable medical resources, but also place a heavy burden on individuals, their families, and society. 2 Therefore, obtaining a clear perspective on the epidemiological trend of chronic diseases among Chinese residents will provide a foundation for exploring strategies for the prevention and treatment of such diseases in China and for proactively preventing and controlling the incidence and development of such diseases.

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The prevalence, awareness, treatment and control of dyslipidemia among adults in China

Cited by 308 publications

References 19 publications

The prevalence, awareness, treatment, and control of dyslipidemia in northeast China: a population-based cross-sectional survey

The prevalence, awareness, treatment, and control of dyslipidemia in northeast China: a population-based cross-sectional survey

The role of active brown adipose tissue (aBAT) in lipid metabolism in healthy Chinese adults

Analysis of epidemiological trends in chronic diseases of Chinese residents

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