Scholars who study public opinion and American foreign policy have accepted what Rathbun et al. (2016) call the “Vertical Hierarchy Model,” which says that policy attitudes are determined by more abstract moral ideas about right and wrong. This article turns this idea on its head by introducing the Prejudice First Model, arguing that foreign policy preferences and orientations are driven by attitudes toward the groups being affected by specific policies. Three experiments are used to test the utility of this framework. First, when conservatives heard about Muslims killing Christians, as opposed to the opposite scenario, they were more likely to support a humanitarian intervention and agree that the United States has a moral obligation to help those persecuted by their governments. Liberals showed no religious preference. When the relevant identity group was race, however, liberals were more likely to want to help blacks persecuted by whites, while conservatives showed no racial bias. In contrast, the degree of persecution mattered relatively little to respondents in either experiment, and the effects of moral foundations were shown to be generally weak relative to those of prejudice. In another experiment, conservatives adopted more isolationist policies after reading a text about the country becoming more liberal, as opposed to a paragraph that said the United States was a relatively conservative country. While not necessarily contradicting the Vertical Hierarchy Model, the results indicate that under most conditions the Prejudice First Model presents a better lens through which to understand how foreign policy preferences are formed.