The possible molecular evolution of sapoviruses by inter- and intra-genogroup recombination

Anjos, Karoline dos; Lima, Lídia Maria Pinto de; Silva, Paula Andreia; Inoue‐Nagata, Alice K.; Nagata, Tatsuya

doi:10.1007/s00705-011-1079-8

Cited by 12 publications

(15 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The GI.1 strain is commonly found worldwide, in studies conducted in Brazil, Thailand and China 17 , 13 , 30 . One sample presented the same genotype (GI.2) in both regions showing high similarity (99%) with the strain detected in midwest Brazil 18 . Genotype GI.2 is more associated with outbreaks and sporadic cases of AGE 31 .…”

Section: Resultsmentioning

confidence: 84%

“…Nevertheless, in Brazil, there are limited data, considering the small number of studies available 16 , 17 , 18 , 19 . Thus, the present study aimed to investigate the SaV occurrence among hospitalized children with acute gastroenteritis from Manaus, Amazonas State, and also to improve the data on the molecular epidemiology of this virus in Brazil.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Sapoviruses in Children With Acute Gastroenteritis From Manaus , Amazon Region, Brazil, 2010-2011

Reymão

Hernandez

Costa

et al. 2016

Rev. Inst. Med. trop. S. Paulo

View full text Add to dashboard Cite

SUMMARYSapoviruses (SaVs) are responsible for acute gastroenteritis in humans, especially children and the elderly. In Brazil, data on SaVs infections are very limited, especially in Northern Brazil. Here, we investigated the occurrence of SaVs in samples from hospitalized children under ten years old that presented acute gastroenteritis. Positive samples were genotyped and phylogenetic analysis was performed using prototype strains sequences obtained from GenBank database. In total, 156 fecal samples were screened by RT-PCR for SaVs. A positivity rate of 3.8% (6/156) was found in children under three years of age. Four genotypes were detected: GI.I, GI.2 and GII.2?-GII.4?/GII.4, suggesting a possible inter-genotypes recombination. Most infections (83.3%) occurred between August and September. The positivity was similar to that found in other countries and genotyping demonstrated the presence of distinct genotypes. To our knowledge, this is the first study reporting the circulation of SaVs in Manaus, state of Amazonas, Amazon region, Brazil.

show abstract

Section: Resultsmentioning

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Sapoviruses in Children With Acute Gastroenteritis From Manaus , Amazon Region, Brazil, 2010-2011

Reymão

Hernandez

Costa

et al. 2016

Rev. Inst. Med. trop. S. Paulo

View full text Add to dashboard Cite

show abstract

“…Therefore, differences in genome organization, the less-conserved RdRp-VP1 boundary, and/or replication mechanisms could limit diversification of sapoviruses by means of RdRp-VP1 recombination. While recombinant and putative parental sapovirus strains have been reported for multiple strains [8,11,12], parental donors for viruses have not yet been detected in nature in many cases [6,7,9]. Further surveillance and phylogenetic analyses will be needed to establish whether recombination is a major driver of sapovirus evolution.…”

Section: Genotypementioning

confidence: 99%

“…Based on the genetic differences of the VP1-encoding sequences, human sapoviruses are phylogenetically clustered into four genogroups (GI, GII, GIV and GV), with each genogroup further clustered into multiple genotypes [1,4]. Discrepancies in the phylogenetic clustering can occur when using different genomic regions, particularly those encoding the RdRp and VP1, and this has led to the identification of intra-and inter-genogroup recombinant strains [1,[5][6][7][8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Genomic Analyses of Human Sapoviruses Detected over a 40-Year Period Reveal Disparate Patterns of Evolution among Genotypes and Genome Regions

Tohma

Kulka

Coughlan

et al. 2020

Viruses

View full text Add to dashboard Cite

Human sapovirus is a causative agent of acute gastroenteritis in all age groups. The use of full-length viral genomes has proven beneficial to investigate evolutionary dynamics and transmission chains. In this study, we developed a full-length genome sequencing platform for human sapovirus and sequenced the oldest available strains (collected in the 1970s) to analyse diversification of sapoviruses. Sequence analyses from five major genotypes (GI.1, GI.2, GII.1, GII.3, and GIV.1) showed limited intra-genotypic diversification for over 20–40 years. The accumulation of amino acid mutations in VP1 was detected for GI.2 and GIV.1 viruses, while having a similar rate of nucleotide evolution to the other genotypes. Differences in the phylogenetic clustering were detected between RdRp and VP1 sequences of our archival strains as well as other reported putative recombinants. However, the lack of the parental strains and differences in diversification among genomic regions suggest that discrepancies in the phylogenetic clustering of sapoviruses could be explained, not only by recombination, but also by disparate nucleotide substitution patterns between RdRp and VP1 sequences. Together, this study shows that, contrary to noroviruses, sapoviruses present limited diversification by means of intra-genotype variation and recombination.

show abstract

“…Potentially new genogroups of porcine SaVs based on partial RNA-dependent RNA polymerase (RdRp) sequences have been reported [9, 10]. Recombinant SaVs have been described in both human and swine hosts [6, 11]. Sapovirus infection of pigs has been described in American, Asian and European countries [5-7, 10, 12-14].…”

mentioning

confidence: 99%

Prevalence and molecular characterization of porcine enteric caliciviruses and first detection of porcine kobuviruses in US swine

et al. 2013

View full text Add to dashboard Cite

The prevalence of porcine sapoviruses (SaVs) and noroviruses (NoVs) in nursing piglets on three pig farms in Ohio was studied. Fecal samples (n = 139) were collected from individual pigs and screened for caliciviruses by RT-PCR. Phylogenetic analysis was conducted using partial sequences of the RNA polymerase region. Three different SaV genogroups, including a newly emerging one (DO19 Korea-like) were detected. No NoVs were detected. Kobuviruses, emerging members of the family Picornaviridae, were detected by primers designed for SaV. To our knowledge, this is the first report of porcine DO19 Korea-like SaV and kobuvirus in the United States.

show abstract

The possible molecular evolution of sapoviruses by inter- and intra-genogroup recombination

Cited by 12 publications

References 34 publications

Sapoviruses in Children With Acute Gastroenteritis From Manaus , Amazon Region, Brazil, 2010-2011

Sapoviruses in Children With Acute Gastroenteritis From Manaus , Amazon Region, Brazil, 2010-2011

Genomic Analyses of Human Sapoviruses Detected over a 40-Year Period Reveal Disparate Patterns of Evolution among Genotypes and Genome Regions

Prevalence and molecular characterization of porcine enteric caliciviruses and first detection of porcine kobuviruses in US swine

Contact Info

Product

Resources

About