The phytoalexin camalexin induces fundamental changes in the proteome of Alternaria brassicicola different from those caused by brassinin

Pedras, M. Soledade C.; Abdoli, Abbas

doi:10.1016/j.funbio.2013.11.005

Cited by 13 publications

(8 citation statements)

References 33 publications

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“…In A. thaliana leaves both biotrophic and necrotrophic plant pathogens induced camalexin formation (Thomma et al, 1999 ). A. brassicicola could detoxify camalexin but at much slower rate than phytoalexin brassinin from Brassicaceae (Pedras et al, 2014 ).…”

Section: Phytotoxins Phytoalexins and Special Smsmentioning

confidence: 99%

Secondary metabolites in fungus-plant interactions

2015

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Fungi and plants are rich sources of thousands of secondary metabolites. The genetically coded possibilities for secondary metabolite production, the stimuli of the production, and the special phytotoxins basically determine the microscopic fungi-host plant interactions and the pathogenic lifestyle of fungi. The review introduces plant secondary metabolites usually with antifungal effect as well as the importance of signaling molecules in induced systemic resistance and systemic acquired resistance processes. The review also concerns the mimicking of plant effector molecules like auxins, gibberellins and abscisic acid by fungal secondary metabolites that modulate plant growth or even can subvert the plant defense responses such as programmed cell death to gain nutrients for fungal growth and colonization. It also looks through the special secondary metabolite production and host selective toxins of some significant fungal pathogens and the plant response in form of phytoalexin production. New results coming from genome and transcriptional analyses in context of selected fungal pathogens and their hosts are also discussed.

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Section: Phytotoxins Phytoalexins and Special Smsmentioning

confidence: 99%

Secondary metabolites in fungus-plant interactions

2015

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“…Thus, A. brassicicola under brassinin stress redirects metabolic flux to affect the TCA cycle and PP pathway, both important for producing energy in the form of NADPH and ATP. Similar studies with 0.1 mM camalexin [71] identified a total of 158 proteins exhibiting significant changes in expression, of which 45 were up-regulated and 113 down-regulated relative to controls. The majority of differentially expressed proteins are those involved in metabolism, protein processing, genetic information processing, protein folding (chaperones) and cellular processes.…”

Section: Stress Responses In Eukaryotic Microorganismsmentioning

confidence: 66%

Proteomic Studies of the Effects of Different Stress Conditions on Central Carbon Metabolism in Microorganisms

2015

J Proteomics Bioinform

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“…Another explanation may be the plant's secretion of a specific compound (or compounds) against the pathogen at the first contact, which might be equivalent to fungal FB 1 . Some compounds with antifungal activities were previously reported, including phytoalexins, for instance, pisatin from Pisum sativum L. against Fusarium solani, resveratrol from grapes against yeast or camalexin from Arabidopsis thaliana against Alternaria brassiciola [26][27][28].…”

Section: Discussionmentioning

confidence: 99%

“…So far, researchers were focused on the impact of the pathogen on plant gene expression and metabolism. On the contrary, the effect of plant metabolites with antifungal activity like camalexin, pisatin and resveratrol were less studied and fungal genes and biochemical pathways associated with the response against plant effectors are still not well-researched and understood [26][27][28]. In the case of Fusarium, reports on mechanisms occurring in the plant's organism are available, but limited information has been gathered about molecular mechanisms of the reaction of Fusarium under biotic stress conditions.…”

Section: Introductionmentioning

confidence: 99%

The Impacts of Asparagus Extract Fractions on Growth and Fumonisins Biosynthesis in Fusarium Proliferatum

Witaszak

Lalak-Kańczugowska

Waśkiewicz

et al. 2020

Toxins

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Asparagus is a genus consisting of over two hundred species of perennial plants. Fusarium proliferatum is a major asparagus pathogen and it biosynthesizes a variety of mycotoxins, of which fumonisins B are prevalent. Our previous studies on F. proliferatum strains indicated that asparagus extract affects the expression of FUM1 gene, encoding polyketide synthase, a key enzyme of the FUM gene cluster governing the biosynthesis of fumonisins. An asparagus-derived F. proliferatum strain increased fumonisin B1 production after extract fractions’ addition, reaching the maximum 2 or 24 h after treatment. The cultures yielded between 40 and 520 mg of dry weight of mycelia after 14 days of cultivation. The differences in fungal biomass amounts between the whole extract and its fractions may result from synergistic effect of all bioactive compounds present in asparagus extract. Among extract fractions, the methanolic fraction had the highest effect on the dry weight of the mycelium reaching about a 13-fold increase compared to the control. Furthermore, we measured the relative expression of the FUM1 gene. Due to the possible antifungal activity of tested extract fractions, future research will be focused on the identification of the Asparagus officinalis L. compounds responsible for this activity.

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The phytoalexin camalexin induces fundamental changes in the proteome of Alternaria brassicicola different from those caused by brassinin

Cited by 13 publications

References 33 publications

Secondary metabolites in fungus-plant interactions

Secondary metabolites in fungus-plant interactions

Proteomic Studies of the Effects of Different Stress Conditions on Central Carbon Metabolism in Microorganisms

The Impacts of Asparagus Extract Fractions on Growth and Fumonisins Biosynthesis in Fusarium Proliferatum

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