This study presents a case analysis as an exemplification of using the Semantic Differential (DS) for the assessment of the changes of meaning and its structure in individual cases in therapeutic contexts.This work entails an extension of the previous study (Gil Escudero y Rodriguez Zafra, 2012) where results about the efficiency of Personal Development Groups (PGG) to the change of meaning of some main psychological concepts of participants in these groups were presented. These changes of meaning are considered as indicators of the emotional, attitudinal and cognitive changes that usually turn out as a result of the participation in such intensive group experiences. The joint analysis of the case data indicates that, after participation in the intensive group experience, the I is valued more and is considered as more benign, serene, with greater subjective well-being, stronger and more dynamic, the perception is perceived. Group as more positive when considering it better and more valuable, more communicative and affective, stronger and more dynamic, and more complete and authentic; Life is valued more positively, perceiving itself as more good and valuable, more authentic and with greater well-being. No sufficiently significant changes were found in the averages of the group of participants in the CPG in the evaluation of the Mother and the Father. In general, there is a general improvement in mood that is reflected in the overall increase in the average response to the DS as a whole.