The peculiarities of Pseudomonas aeruginosa resistance to antibiotics and prevalence of serogroups

Abstract

Summary. Pseudomonas aeruginosa is one of the most common nonfermenting aerobic gramnegative microorganisms identified in clinical specimens of hospitalized patients. The emergence of multidrug-resistant (MDR) Pseudomonas

Pseudomonas Aeruginosa : Arsenal of Resistance Mechanisms, Decades of Changing Resistance Profiles, and Future Antimicrobial Therapies

“…Furthermore, the resistance rates of P. aeruginosa to ticarcillin containing additional β-lactamase inhibitors such as tazobactam or clavulanate have been reported to be as high as 77% and the MIC 50 and MIC 90 were >128 and >128 μg/ml, respectively [37,[43][44][45][46][47]. The resistance rates of P. aeruginosa to piperacillin have been reported in different surveillance studies from different regions to be as low as 3.9% to as high as 50% with MIC 50 and MIC 90 values of >256 and >256 μg/ ml, respectively [48][49][50][51]. When tazobactam was included, resistance rates reported from different parts of the world ranged from 9% to 29% [40,[43][44]46,49,[52][53][54][55][56][57][58][59].…”

“…The sensitivity of the isolates to piperacillin reflects the infrequent use of piperacillin, which may be attributed to its high cost and relatively lower prescription rates, while the extensive use of piperacillin in other settings elsewhere is a major driving factor to higher resistance rates. The resistance rates of P. aeruginosa clinical isolates to carbenicillin were found to range from 9% to 46.1% [48,53].…”

Class 1 Integron in Pseudomonas aeruginosa Isolates From Different Places and Devices of ICU in Babol, Iran

“…According to the data released by Center for Disease Control (USA), P. aeruginosa is the fifth most common pathogen among hospital microorganisms which causes 10% of all hospital acquired infections (HAI) (1)(2)(3). This organism has a considerable compatibility ability with the environment and acquires antibiotic resistant genes and can be transmitted in hospital environment from one patient to another (4,5).…”

Retrospective Analysis of Antibiotic Susceptibility Patterns of Respiratory Isolates of Pseudomonas Aeruginosa in a Chest Diseases Public Hospital

“…The rate of strains resistant to all antibiotic groups was 4% (resistant to all four groups). The rate of MDR strains was reported as 6.4% in the study of Al-Jasser and Elkhizzi (23) from Saudi Arabia, 5.7% by Raja and Singh (25) from Malaysia, 9.8% by Gailiene et al (29) from Lithuania, and 3.3% by Yoshimura et al (30) from Japan. It can be said that the MDR strain rate in our study is higher than that in other countries.…”