The own method and program of isotopic quantitative assessment of perfusion in muscles of upper limbs

Niewiadomski, Dariusz; Tryniszewski, Wiesław; Marzec, Wojciech; Brocki, Marian; Mikosiński, Jacek; Raciborska, Iwona; Maziarz, Zbigniew

doi:10.5603/nmr.2014.0004

Cited by 4 publications

(1 citation statement)

References 10 publications

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“…99m Technetium-sestamibi ( 99m Tc-MIBI) single-photon emission computed tomography (SPECT/CT) SPECT/CT is a widely used method for myocardial perfusion as it is able to reflect blood perfusion of the myocardium [13]. Several studies have revealed its role in evaluating the perfusion and mitochondrial function in skeletal muscles [14][15][16]. Recently, our center has established a screening method based on 99m Tc-MIBI SPECT/CT in CD [17].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of single-photon emission computed tomography aided botulinum toxin injection in cervical dystonia: A double-blind, randomized study

Teng

Djibo

Chen

et al. 2021

Parkinsonism & Related Disorders

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Background: Although single-photon emission computed tomography (SPECT/CT) could help to predetermine dystonic muscles in patients with cervical dystonia (CD), its efficacy in aiding botulinum toxin injection is undetermined. This randomized, double-blinded study aimed to assess the efficacy of SPECT/CT aided botulinum toxin injection in CD. Methods: Patients were randomized into study group (candidate muscles selected by SPECT/CT and clinical evaluation) or control group (clinical evaluation). Follow-ups were done at two weeks (T1), one (T2), three (T3) and six months (T4). The primary outcomes included symptom improvement assessed using Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) and Tsui score at T2. Results: A total of 122 patients were enrolled and 108 patients accomplished the study. For primary outcomes, the study group had significantly better symptom improvement at T2

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Section: Introductionmentioning

confidence: 99%

Efficacy of single-photon emission computed tomography aided botulinum toxin injection in cervical dystonia: A double-blind, randomized study

Teng

Djibo

Chen

et al. 2021

Parkinsonism & Related Disorders

View full text Add to dashboard Cite

show abstract

[99mTc]MIBI SPECT/CT for Identifying Dystonic Muscles in Patients with Primary Cervical Dystonia

et al. 2019

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The efficacy of single-photon emission computed tomography in identifying dystonic muscles in cervical dystonia

Feng¹,

Zhang²,

Djibo³

et al. 2020

Nuclear Medicine Communications

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Introduction The key point for botulinum toxin type A injection in treating cervical dystonia is to accurately identify dystonic muscles. This study aimed to evaluate the efficacy of 99mtechnetium-sestamibi single-photon emission computed tomography in identifying target muscles in cervical dystonia. Methods In the study group (n = 18), target muscles were selected according to clinical evaluation combined with 99mtechnetium-sestamibi single-photon emission computed tomography, while in the control group (n = 18), target muscles were selected by clinical evaluation alone. All patients were followed-up at 2 weeks, 1, 3 and 6 months after botulinum toxin type A injection. The primary outcomes were the reduction rates in Toronto Western Spasmodic Torticollis Rating Scale and Tsui score at 1 month. Results Although the reduction rates in Toronto Western Spasmodic Torticollis Rating Scale and Tsui scores were not different between the two groups at 2 weeks and 1 month, the reduction rates in both scores were significantly higher in the study group at 3 and 6 months. The number of patients receiving re-injection within 6 months was significantly lower in the study group. Also, the re-injection interval was significantly longer in the study group. In the study group, more deep cervical muscles were injected, which concerns especially semispinalis capitis, longissimus capitis, and obliques capitis inferior muscles. Conclusion 99mtechnetium-sestamibi single-photon emission computed tomography is a useful method for screening target muscles in cervical dystonia. It helps clinicians draw a ‘blueprint’ for the distribution of dystonic muscles before botulinum toxin type A injection.

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The own method and program of isotopic quantitative assessment of perfusion in muscles of upper limbs

Abstract: BACKGROUND:The issue of blood flow in muscles has been dealt with for many years. However, most often it was assessed qualitatively with standard vascular examinations. The quantitatively perfusion assessment is indispensable in the normal and

Cited by 4 publications

References 10 publications

Efficacy of single-photon emission computed tomography aided botulinum toxin injection in cervical dystonia: A double-blind, randomized study

Efficacy of single-photon emission computed tomography aided botulinum toxin injection in cervical dystonia: A double-blind, randomized study

[99mTc]MIBI SPECT/CT for Identifying Dystonic Muscles in Patients with Primary Cervical Dystonia

The efficacy of single-photon emission computed tomography in identifying dystonic muscles in cervical dystonia

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