The normal closure of the ventricular septum

Mitchell, Shiela C.; Berendes, Heinz W.; Clark, William M.

doi:10.1016/0002-8703(67)90429-2

Cited by 28 publications

(8 citation statements)

References 6 publications

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“…When evaluating the incidence of cardiac anomalies, fac tors such as population distribution, ethnic differences, diagnostic method and the age at diagnosis should all be considered [13][14][15][16]. The rate of congenital heart disease in low-birth-weight infants is known to be higher than that among normalbirth-weight infants [ 1,16,17], Among 29 neonates with a birth-weight of less than 2,500 g in our series, 2 neonates had cardiac defects; and a moderate TR and muscular VSD in 1 each. By 1 month of age, the latter had sponta neously closed.…”

Section: Discussionmentioning

confidence: 99%

Incidence of Structural Cardiac Disorders in Neonates: An Evaluation by Color Doppler Echocardiography and the Results of a 1-Year Follow-Up

Ooshima

Fukushige

Veda³

1995

Cardiology

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Non-biased 502 consecutive neonates were examined by sectorial and color Doppler flow imaging at a mean age of 1.0 day (SD 0.4). Patent foramen ovale was present in 266 (53%) and transient patent ductus arteriosus in 104 (21%). Cardiac disorders were recognized in 19 (3.8%); ventricular septal defect (VSD) in 10; atrial septal defect (ASD) in 4; pulmonary stenosis in 2; aortic stenosis, endocardial cushion defect and tricuspid regurgitation in 1 each. With a spontaneous closure of 8 VSDs and 4 ASDs during the first 12 months, the incidences of cardiac malformation were, consequently, 3.2% at 1 month, 1.4% at 6 months and 1.0% at 12 months.

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Section: Discussionmentioning

confidence: 99%

Incidence of Structural Cardiac Disorders in Neonates: An Evaluation by Color Doppler Echocardiography and the Results of a 1-Year Follow-Up

Ooshima

Fukushige

Veda³

1995

Cardiology

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“…cor triloculare biatriatum or single ventricle) were also excluded from the study IV. Spontaneous closure in cases with muscular VSD was estimated on 30-35%, while it occurred about 10-15% in cases with membranous [28]. Thus, some experts considered at least muscular VSD as "delayed physiological development" rather than as a CA [16].…”

Section: Study Design Of Cases With Vsdmentioning

confidence: 99%

Ventricular septal defects in function of maternal sociodemographic aspects

Vereczkey¹,

Kósa²,

Csáky-Szunyogh

et al. 2012

Open Medicine

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AbstractThe objective of our project is to reveal the possible etiological factors of different congenital cardiovascular abnormalities. In this study, we evaluated single ventricular septal defect (VSD) after surgical correction or with lethal outcome. The birth outcomes of these cases in the function of maternal socio-demographic features were evaluated. Data are based on 1,659 VSD cases, 2,534 matched controls and 38,151 all controls without any defects, in addition in the mothers of 19,393 malformed controls with other isolated defects in the population-based large dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities. VSD had mild female excess with a higher rate of preterm birth and mainly low birth weight indicating intrauterine growth restriction of affected fetuses, particularly in males and full-term or average weighted cases. The mothers of cases with VSD had lower socioeconomic status and higher rate of smoking and particularly drinking habit. The evaluation of medically recorded pregnancy complications showed an association of gestational diabetes with a higher risk of VSD. In conclusion, the association of small localized size of VDS and obvious fetal growth restriction needs further explanation in these cases, while gestational diabetes, lower socioeconomic status and adverse lifestyle of pregnant women may have a role in the origin of VSD.

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“…The incidences of CHD and VSD in premature infants'0' 23,37 have been based on prematurity defined by weight alone, although Mitchell and associates37 found that birth weight and gestational age correlated well in their series. Whichever definition is used, prematurity must be taken into account when assessing the incidence of CHD and VSD, since any series with an unusual excess or deficit of premature infants will have a distorted incidence of these lesions.…”

Section: Studies In Childhoodmentioning

confidence: 99%

“…The best available esti-mates10 23, 25-27 37 (table 8) indicate an incidence of 1.28 to 3.30/1,000 live births. The lower incidences are probably too low; for example, in our study'0 several infants with all the clinical criteria of VSD were not catheterized and not included in the series.…”

Section: Th Chd In Stillbirthsmentioning

confidence: 99%

Natural History of Congenital Heart Disease

Hoffman

1968

Circulation

123

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It is difficult to make prognoses and decisions on therapy of individuals with congenital heart disease (CHD) and plan efficiently for medical services and training programs because studies on the incidence and relative frequency of different types of CHD at birth, mortality rates, times of death, and prevalence rates in children and adults are incomplete or unrepresentative. The present study assesses the merits of previous surveys and attempts to indicate the best information about these rates. Specific attention has been directed to data on ventricular septal defect (VSD), with an estimated incidence of at least 20/10,000 live births; about 10% of these children died before 15 years of age. There should thus be about 18/10,000 surviving school children with VSD, yet the most intensive school surveys show only about half this number. This supports the suggestion that there is a high incidence (perhaps 50%) of spontaneous closure of VSD during childhood. Spontaneous closure may also occur frequently after childhood, but this conclusion needs to be confirmed by better surveys.

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The normal closure of the ventricular septum

Cited by 28 publications

References 6 publications

Incidence of Structural Cardiac Disorders in Neonates: An Evaluation by Color Doppler Echocardiography and the Results of a 1-Year Follow-Up

Incidence of Structural Cardiac Disorders in Neonates: An Evaluation by Color Doppler Echocardiography and the Results of a 1-Year Follow-Up

Ventricular septal defects in function of maternal sociodemographic aspects

Natural History of Congenital Heart Disease

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