Abstract:To investigate the application of inner ear 3-dimensional fluid-attenuated inversion recovery (3D-FLAIR) magnetic resonance imaging (MRI) in patients with sudden sensorineural hearing loss (SSNHL) accompanied by inner ear hemorrhage. A total of 1252 SSNHL patients who were admitted from January 2010 to April 2018 were included in the study. The patients' clinical features, complete blood counts, coagulation profiles, audiometry data, and MRI scans were retrospectively reviewed. Twenty-four patients had high la… Show more
“…Inner ear MRI abnormalities include inner ear haemorrhage, protein deposition and BLB‐B. This is usually due to haemorrhage or inflammation 22,23 . This study found no correlation between TEG and inner ear MRI.…”
Section: Discussionmentioning
confidence: 62%
“…This is usually due to haemorrhage or inflammation. 22,23 This study found no correlation between TEG and inner ear MRI. In patients with normal MRI, TEG hypercoagulation and hypocoagulation were found in 32% and 8% of patients, respectively, and in patients with abnormal MRI results, TEG hypercoagulation and hypocoagulation were found in 44.2% and 7.7% of patients, respectively.…”
Objectives: To explore the association between thromboelastography and the clinical features as well as the prognosis of sudden sensorineural hearing loss (SSNHL).
“…Inner ear MRI abnormalities include inner ear haemorrhage, protein deposition and BLB‐B. This is usually due to haemorrhage or inflammation 22,23 . This study found no correlation between TEG and inner ear MRI.…”
Section: Discussionmentioning
confidence: 62%
“…This is usually due to haemorrhage or inflammation. 22,23 This study found no correlation between TEG and inner ear MRI. In patients with normal MRI, TEG hypercoagulation and hypocoagulation were found in 32% and 8% of patients, respectively, and in patients with abnormal MRI results, TEG hypercoagulation and hypocoagulation were found in 44.2% and 7.7% of patients, respectively.…”
Objectives: To explore the association between thromboelastography and the clinical features as well as the prognosis of sudden sensorineural hearing loss (SSNHL).
“…This theory explains why full IAC involvement of tumor is a risk factor of cochlear obliteration. Labyrinthine hemorrhage is another possible cause of cochlear obliteration and can be detected by abnormal hyperintense signal in pre-contrast T1W or FLAIR MRI [Vakkalanka et al, 2000;Chen et al, 2019]. High signal intensity on T1W image is probably caused by intracellular methemoglobin or protein macromolecule deposition following erythrocyte destruction.…”
<b><i>Introduction:</i></b> The aim of this study was to better understand the onset time and factors associated with cochlear obliteration following translabyrinthine approach (TLA) surgery for large cerebellopontine angle tumors. <b><i>Methods:</i></b> This retrospective cohort study included 117 patients with large cerebellopontine angle tumor (tumor diameter >2 cm) treated by TLA surgery from June 2011 to March 2019 in a single tertiary referral center. The Kaplan-Meier method with log-rank test was used to estimate cochlear patency survival and the association between survival and covariates, and the Cox proportional hazards regression analysis was used to identify possible factors associated with cochlear obliteration. <b><i>Results:</i></b> Of the 117 patients included in our analysis, the median follow-up was 24.8 months. There were 30 (25.6%) patients in the cochlear obliteration group, and 87 (74.4%) in the patent cochlear group. Various degrees of cochlear obliteration was found in 25.6% patients in final MRI scan, comprised of 50% grade I, 30% grade II, and 20% grade III. Cochlear patency survival curves showed 94.0% at 3 months, 73.0% at 18 months, which plateaued after 20 months with a survival rate of 71.6%. In the multivariate Cox proportional hazards model, patients presented with postoperative hyperintense T1W cochlear signal had poorer cochlear patency survival compared to isointense T1W (HR = 4.15). Similarly, postoperative deteriorated facial function (HR = 4.52) and full IAC involvement of tumor (HR = 2.33) demonstrated a higher risks of cochlear obliteration after TLA surgery. <b><i>Conclusion:</i></b> The 2-year estimated cochlear patency rate was 71.6% in patients that received TLA. Cochlear obliteration can develop as early as 3 months post-surgery, with no new obliteration 20 months after the surgery and half of these patients got severe obliteration. Three factors associated with cochlear obliteration were identified including full IAC involvement of tumor, postoperative facial function deterioration, and postoperative hyperintense T1W cochlear signal.
“…As a result of the widespread use of Magnetic Resonance Imaging (MRI) acute sensorineural hearing loss (SNHL) due to hemorrhage in inner ear has been reported in the literature [16]. Also, especially in patients with underlying coagulation disorders, cases of SNHL as a result of ILH have been reported [17,18].…”
Objective: We aimed to investigate the incidence of hearing loss in patients followed up for Chronic Immune Thrombocytopenia Purpura (ITP).
Material and Methods: All patients over the age of 18 who referred to the hematology outpatient clinic between January and June 2020 and followed up with the diagnosis of Chronic ITP were included in the study. Hearing tests of patients diagnosed with Chronic ITP and received first-line treatment (IVIG and corticosteroid) for any reason other than ear diseases during their treatment were evaluated retrospectively. Patients with a history of hearing loss, perforation of the tympanic membrane or who had any squeal due to a previous chronic ear infection and patients who had a previous ear operation were excluded from the study. In addition, patients' age, gender, time of ITP diagnosis, platelet values at the time of diagnosis, platelet values during audiological evaluation, concomitant disease, history of splenectomy, additional drug use and ISTH-SSC Bleeding Evaluation Score data were also recorded.
Results: Of the 34 cases, 58.8% (n=20) were female and 41.2% (n=14) were male. The mean age was 49.06±18.26. Similarly, when compared, usage of IVIG/Methylprednisolone, IVIG/ Methylprednisolone /Eltrombopag, and IVIG/Methylprednisolone /Rituximab/Eltrombopag was not found to be a factor that would cause hearing loss (p>0.05). No statistical correlation was found between ISTH-SSC and time of diagnosis (months) and hearing loss (p>0.05).
Conclusion: Parameters such as various drugs used in the course of Chronic ITP disease, age, gender, time of diagnosis, and presence of concomitant disease do not cause hearing loss.
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