Objectives: To explore the association between thromboelastography and the clinical features as well as the prognosis of sudden sensorineural hearing loss (SSNHL).

IntroductionThis study aimed to investigate the clinical features and prognosis of sudden sensorineural hearing loss in patients with lateral semicircular canal (LSCC) malformation.MethodsThis study enrolled patients with LSCC malformation and sudden sensorineural hearing loss (SSNHL) who were admitted to Shandong ENT Hospital between 2020 and 2022. We collected and analyzed data on examinations of audiology, vestibular function, and imaging records of patients and summarized the clinical characteristics and prognosis of these patients.ResultsFourteen patients were enrolled. Patients with LSCC malformation was noted in 0.42% of all SSNHL cases during the same period. One patients had bilateral SSNHL and the rest had unilateral SSNHL. Of them, eight and six patients had unilateral and bilateral LSCC malformations, respectively. Flat hearing loss was noted in 12 ears (80.0%) and severe or profound hearing loss was noted in 10 ears (66.7%). After treatment, the total efficacy rate of SSNHL with LSCC malformation was 40.0%. Vestibular function was abnormal in all patients, but only five patients (35.7%) had dizziness. There were statistically significant differences in the vestibular functions between patients with LSCC malformation and matched patients without the malformation hospitalized during the same period (p < 0.05).ConclusionPatients with SSNHL and LSCC malformation had flat-type and severe hearing loss and worse disease prognosis compared to those with SSNHL without LSCC malformation. Vestibular function is more likely to be abnormal; however, there was no significant difference in vestibular symptoms between patients with and without LSCC malformation. LSCC is a risk factor for the prognosis of SSNHL.

In order to decrease the casualties, monitor the real-time motion and safety of the fireman in fire scene, an accurate, efficient and low-cost attitude detector is designed. To monitor the attitude angle in real time, the extend Kalman filter for attitude detector based on quaternion is presented internally. To improve the accuracy detector uses the three-axis MEMS gyroscope with range of 1200 ° / s, and sensor data is processed by using a dynamic zero-calibration method and a configurable Parks-McClellan window FIR low-pass filter. The three-axis MEMS accelerometer and compass are also used.In consideration of the compensation of the incline the affect of soft and hard magnet, and the centripetal force, automatic calibration system is designed to be adapted in different environment to guarantee the dynamic correction. At the same time , detector integrates the wireless radio frequency technology and the OpenGL representation of the real-time human motion in 3D are also given. The results of experiment show that the heading and attitude data computed from the accelerometers and magnetometers is used for compensating the drift of gyroscopes, and the dynamic accuracy is controlled within 2 degree, meanwhile, the static accuracy is no more than 0.5 degree. Through the test of principle prototype, the feasibility and stability of the attitude detector are also demonstrated.