The modified cam clay model for constrained compression of human morsellised bone: Effects of porosity on the mechanical behaviour

On the applicability of bovine morsellized cortico-cancellous bone as a substitute for human morsellized cortico-cancellous bone for in vitro mechanical testing

“…The denser trabecular structure, higher fat content of bovine MCB and higher stiffness and compressive strength of cortical bovine bone may explain the differences observed. The large difference in parameter values for human and bovine MCB, clearly illustrate that material parameters useful for finite element modelling of MCB should be determined for human MCB, as presented in Lunde et al (2008a) and Lunde and Skallerud (2008).…”

“…a Indicate parameters that were not normally distributed. (Lunde et al, 2008a;Lunde and Skallerud, 2008), the data for samples containing no liquid have not been presented before. distribution were different for human and bovine MCB.…”

“…The properties of MCB are crucial for the survival of the new joint and have been the subject of many experimental studies. Several authors have investigated different aspects of the complex mechanical behaviour of MCB (Giesen et al, 1999;Voor et al, 2000;Phillips et al, 2006a, b;Fosse et al, 2006a;Lunde et al, 2008a, c;Lunde and Skallerud, 2008). Others have investigated the effect of different treatments of the MCB, such as varying water and fat content (Voor et al, 2000(Voor et al, , 2004Fosse et al, 2006c), impaction technique and magnitude (Fosse et al, 2004;Lunde et al, 2008b), grinding mill (Fosse et al, 2006b;Grimm, 2003) and the addition of biomaterial particles to the MCB (Grimm, 2003;Blom et al, 2002;Verdonschot et al, 2001).…”

Morsellised sawbones is an acceptable experimental substitute for the in vitro elastic and viscoelastic mechanical characterisation of morsellised cancellous bone undergoing impaction grafting

“…Further complicating factors in any comparison across studies include the influence of the fat content of the MCB which has been shown to significantly influence the consolidation behaviour [22,25]. The advantage of morsellised sawbones in this regard is in its standardized nature with zero instrinsic fat content, which makes it attractive when attempting to control experimental conditions.…”

“…This then offers the possibility of employing computer based stress analysis techniques to help inform experimental and clinical observations (e.g. Phillips et al [45], Lunde & Skallerud [25], Albert et al [46])…”